Accurate platelet counting in an insidious case of pseudothrombocytopenia

Clinical Chemistry and Laboratory Medicine

Volumn 37, Issue 11-12, 1999, Pages 1063-1066

  Lombarts, Arnold J P F ^a   Zijlstra, Jelle J ^a   Peters, Richard H M ^a   Thomasson, Cees G ^a   Franck, Paul F H ^a  

^a LEYENBURG HOSPITAL   (Netherlands)

Author keywords

Blood cell counters; CTAD; Gentamicin; Iloprost; Platelet counting; Pseudothrombocytopenia

Indexed keywords

ACID CITRATE DEXTROSE; ANTICOAGULANT AGENT; CITRIC ACID; EDETIC ACID; GENTAMICIN; ILOPROST;

AGED; ARTICLE; CASE REPORT; FEMALE; HUMAN; HUMAN CELL; PRIORITY JOURNAL; THROMBOCYTE AGGREGATION; THROMBOCYTE COUNT; THROMBOCYTOPENIA;

EID: 0033371016     PISSN: 14346621     EISSN: None     Source Type: Journal    
DOI: 10.1515/CCLM.1999.155     Document Type: Article

References (12)

1. Makris PE, Foka Z, Gerotziafas GT, Kioumi A, Pithara E. Pseudothrombocytopenia: a rare phenomenon. Clin Appl Thrombosis/Hemostasis 1998; 4:167-9.
2. Qureshi BH. Clinical pathology rounds. EDTA-dependent Pseudothrombocytopenia. Lab Med 1998; 29:471-3.
3. Fiorin F, Steffan A, Pradella P, Bizzaro N, Potenza R, De Angelis V. IgG platelet antibodies in EDTA-dependent pseudothrombocytopenia bind to platelet membrane glycoprotein Ilb. Am J Clin Pathol 1998; 110:178-83.
4. Schrezenmeier H, Müller H, Gunsilius E, Heimpel H, Seifried E. Anticoagulant-induced pseudothrombocytopenia and pseudoleucocytosis. Thromb Haemost 1995; 73:506-13.
5. Lombarts AJPF, de Kieviet W. Recognition and prevention of pseudothrombocytopenia and concomitant pseudoleukocytosis. Am J Clin Pathol 1988; 89:634-9.
6. Lombarts AJPF, de Kieviet W, Franck PFH, Baars JD. Recognition and prevention of two cases of erroneous haemocytometry counts due to platelet and white blood cell aggregation. The use of acid citrate dextrose as an auxiliary anticoagulant. Eur J Clin Chem Clin Biochem 1992; 30:429-32.
7. Bower KL, Procopio N, Wystepek E, Glazier J, Mattson JC. Platelet clumps, nucleated red cells, and leukocyte counts: a comparison between the Abbott CELL-DYN® 4000 and Coulter® STKS. Lab Hematol 1998; 4:7-16.
8. Forscher CA, Sussman II, Friedman EW, Solomon V, Spaet TH. Pseudothrombocytopenia masking true thrombocytopenia. Am J Hematol 1985; 18:313-7.
9. Contant G, Goualt-Heilmann M, Martinoli JL. Heparin inactivation during blood storage: its prevention by blood collection in citric acid, theophylline, adenosine, dipyridamole. Thromb Res 1983; 31:365-74.
10. 1 on human platelet function. J Lab Clin Med 1987; 109:184-90.
11. Sakurai S, Shiojima I, Tanigawa T, Nakahara K. Aminoglycosides prevent and dissociate the aggregation of platelets in patients with EDTA-dependent pseudothrombocytopenia. Br J Haematol 1997; 99:817-23.
12. Bartels PCM, Schoorl M, Lombarts AJPF. Screening for EDTA-dependent deviations in platelet counts and abnormalities in platelet distribution histograms in pseudothrombocytopenia. Scand J Clin Lab Invest 1997; 57:629-36.