In vivo cell type-specific gene delivery with retroviral vectors that display single chain antibodies

Gene Therapy

Volumn 6, Issue 12, 1999, Pages 1982-1987

  Jiang, A ^a   Dornburg, R ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

Gene therapy; her2neu; Retroviral vectors; scA; Spleen necrosis virus

Indexed keywords

ANTIBODY; CELL RECEPTOR; CELL SURFACE PROTEIN; VIRUS VECTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBIOTIC RESISTANCE; ANTIBODY COMBINING SITE; ANTIGEN EXPRESSION; ARTICLE; CONTROLLED STUDY; DOG; GENE EXPRESSION; GENE TARGETING; GENETIC TRANSDUCTION; HUMAN; HUMAN CELL; LACTOSE OPERON; MOUSE; NONHUMAN; PERITONEUM; PRIORITY JOURNAL; RETROVIRUS; SCID MOUSE; TARGET CELL; VIRUS INFECTION; VIRUS PARTICLE;

ANIMALS; ANTIBODIES; CELL LINE; DOGS; DRUG RESISTANCE, MICROBIAL; GENE EXPRESSION; GENE THERAPY; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; HELA CELLS; HUMANS; LAC OPERON; MICE; MICE, SCID; RECEPTOR, ERBB-2; RETROVIRIDAE;

ANIMALIA; CANIS FAMILIARIS; RNA VIRUSES; SPLEEN NECROSIS VIRUS; UNIDENTIFIED RETROVIRUS;

EID: 0033370033     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3301043     Document Type: Article

References (30)

1. Miller AD. Retrovirus packaging cells. Hum Gene Ther 1990; 1: 5-14.
2. Anderson WF. Human gene therapy. Nature 1998; 392: 25-30.
3. McCormack JE et al. Anti-vector immunoglobulin induced by retroviral vectors. Hum Gene Ther 1997; 8: 1263-1273.
4. Hunter E, Swanstrom R. Retrovirus envelope glycoproteins. Curr Top Microbiol Immunol 1990; 157: 187-253.
5. Young JAT, Bates P, Willert K, Varmus HE. Efficient incorporation of human CD4 protein into avian leukosis virus particles. Science 1990; 250: 1421-1423.
6. Chu T-H, Dornburg R. Retroviral vector particles displaying the antigen-binding site of an antibody enable cell type-specific gene transfer. J Virol 1995; 69: 2659-2663.
7. Chu T-H, Martinez I, Sheay WC, Dornburg R. Cell targeting with retroviral vector particles containing antibody-envelope fusion proteins. Gene Therapy 1994; 1: 292-299.
8. Russell SJ, Hawkins RE, Winter G. Retroviral vectors displaying functional antibody fragments. Nucl Acid Res 1993; 21: 1081-1085.
9. Chu T-H, Dornburg R. Towards highly efficient cell type-specific gene transfer with retroviral vectors that display a single chain antibody. J Virol 1997; 71: 720-725.
10. Jiang A et al. Cell type-specific gene transfer into human cells with retroviral vectors that display single-chain antibodies. J Virol 1998; 72: 10148-10156.
11. Engelstädter M et al. Targeting human T cells by retroviral vectors displaying antibody domains selected from a phage display library. Hum Gene Ther (in press).
12. Bird RE et al. Single-chain antigen-binding proteins. Science 1988; 242: 423-426.
13. Whitlow M, Filpula D. Single-chain Fv proteins and their fusion proteins. Meth Enzymol 1991; 2: 1-9.
14. Alper O et al. The presence of c-erbB-2 gene product-related protein in culture medium conditioned by breast cancer cell line SK-BR-3. Cell Growth Diff 1990; 1: 591-599.
15. Uckun FM. Severe combined immunodeficient mouse models of human leukemia. Blood 1996; 88: 1135-1146.
16. Dick JE. Future prospects for animal models created by transplanting human haematopoietic cells into immune-deficient mice. Res Immunol 1994; 145: 380-384.
17. Dick JE, Sirard C, Pflumio F, Lapidot T. Murine models of normal and neoplastic human haematopoiesis. Cancer Surv 1992; 15: 161-181.
18. Dick JE. Immune-deficient mice as models of normal and leukemic human hematopoiesis. Cancer Cells 1991; 3: 39-48.
19. Mueller BM, Reisfeld RA. Potential of the SCID mouse as a host for human tumors. Cancer Metast Rev 1991; 10: 193-200.
20. Shen RN, Lu L, Broxmeyer HE. New therapeutic strategies in the treatment of murine diseases induced by virus and solid tumors: biology and implications for the potential treatment of human leukemia, aids, and solid tumors (review). Crit Rev Oncol Hematol 1990; 10: 253-265.
21. Taylor HW, Olson LD. Spectrum of infectivity and transmission of the T-virus. Avian Dis 1972; 16: 330-335.
22. Welsh RM, Cooper NR, Jensen FC, Oldstone MBA. Human serum lysis RNA tumor viruses. Nature 1975; 257: 612-614.
23. Welsh RM, Jensen FC, Cooper NR, Oldstone MBA. Inactivation and lysis of oncornaviruses by human serum. Virology 1976; 74: 432-440.
24. Takeuchi Y et al. Type C retrovirus inactivation by human complement is determined by both the viral genome and the producer cell. J Virol 1994; 68: 8001-8007.
25. Russell DW, Berger MS, Miller AD. The effects of human serum and cerebrospinal fluid on retroviral vectors and packaging cell lines. Hum Gene Ther 1995; 6: 635-641.
26. Takeuchi Y et al. Type c retrovirus inactivation by human complement is determined by both the viral genome and the producer cell. J Virol 1994; 68: 8001-8007.
27. Mikawa T, Fischman DA, Dougherty JP, Brown AMC. In vivo analysis of a new lacZ retrovirus vector suitable for lineage marking in avian and other species. Exp Cell Res 1992; 195: 516-523.
28. Pomerantz RJ, Trono D. Genetic therapies for HIV infections: promise for the future. AIDS 1995; 9: 985-993.
29. Kawai S, Nishizawa M. New procedure for DNA transfection with polycation and dimethyl sulfoxide. Mol Cell Biol 1984; 4: 1172-1174.
30. Martinez I, Dornburg R. Improved retroviral packaging lines derived from spleen necrosis virus. Virology 1995; 208: 234-241.