Epidermal and hepatocyte growth factors stimulate chemotaxis in an intestinal epithelial cell line

American Journal of Physiology - Cell Physiology

Volumn 277, Issue 6 46-6, 1999, Pages

  Polk, D Brent ^a,b   Tong, Wei ^a  

^a VANDERBILT UNIVERSITY   (United States)

^b Department of Pediatrics   (United States)

Author keywords

Cellular migration; Extracellular matrix; Proliferation; Tyrosine kinase

Indexed keywords

EPIDERMAL GROWTH FACTOR; SCATTER FACTOR;

ANIMAL CELL; ARTICLE; CELL MIGRATION; CHEMOTAXIS; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME REGULATION; INTESTINE EPITHELIUM; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ANIMALIA; TRIXIS;

EID: 0033369163     PISSN: 03636143     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpcell.1999.277.6.c1149     Document Type: Article

References (10)

1. Anand-Apte, B., B. R. Zetter, A. Viswanathan, R.-G. Qiu, J. Chen, R. Ruggieri, and M. Symons. Platelet-derived growth factor and fibronectin-stimulated migration are differentially regulated by the Rac and extracellular signal-regulated kinase pathways. J. Biol. Chem. 272: 30688-30692, 1997.
2. Barnard, J. A., R. D. Beauchamp, R. J. Coffey, and H. L. Moses. Regulation of intestinal epithelial cell growth by transforming growth factor type β. Proc. Natl. Acad. Sci. USA 86: 1578-1582, 1989.
3. Barnard, J. A., W. H. Polk, H. L. Moses, and R. J. Coffey. Production of transforming growth factor-α by normal rat small intestine. Am. J. Physiol. 261 (Cell Physiol 30): C994-C1000, 1991.
4. Basson, M. D., I. M. Modlin, S. D. Flynn, B. P. Jean, and J. A. Madri. Independent modulation of enterocyte migration and proliferation by growth factors, matrix proteins, and pharmacologic agents in an in vitro model of mucosal healing. Surgery 112: 299-308, 1992.
5. Basson, M. D., I. M. Modlin, and J. A. Madri. Human enterocyte (Caco-2) migration is modulated in vitro by extracellular matrix composition and epidermal growth factor. J. Clin. Invest. 90: 15-23, 1992.
6. Beaulieu, J.-F., and P. H. Vachon. Reciprocal expression of laminin A-chain isoforms along the crypt-villus axis in the human small intestine. Gastroenterology 106: 829-839, 1994.
7. Blay, J., and K. D. Brown. Epidermal growth factor promotes the chemotactic migration of cultured rat intestinal epithelial cells. J. Cell. Physiol 124: 107-112, 1985.
8. Buck, R. C. Ultrastructural features of rectal epithelium of the mouse during the early phases of migration to repair a defect. Virchows Arch. B Cell. Pathol. 51: 331-340, 1986.
9. Carcamo, J., F. M. B. Weis, F. Ventura, R. Wieser, J. L. Wrana, L. Attisano, and J. Massague. Type I receptors specify growth-inhibitory and transcriptional responses to transforming growth factor β and activin. Mol. Cell. Biol. 14: 3810-3821, 1994.
10. Chen, P., H. Xie, M. C. Sekar, K. Gupta, and A. Wells. Epidermal growth factor receptor-mediated cell motility: phospholipase C activity is required, but mitogen-activated protein kinase activity is not sufficient for induced cell movement. J. Cell. Biol. 127: 847-857, 1994.