Typing for the human Lewis blood group system by quantitative fluorescence-activated flow cytometry: Large differences in antigen presentation on erythrocytes between A1, A2, B, O phenotypes

Vox Sanguinis

Volumn 77, Issue 4, 1999, Pages 227-236

  Larson, Göran ^a   Svensson, Lola ^a   Hynsjö, Lars ^a   Elmgren, Anders ^a   Rydberg, Lennart ^a  

^a SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

PAPAIN; REAGENT;

ANTIGEN PRESENTATION; ARTICLE; BLOOD DONOR; BLOOD GROUP A; BLOOD GROUP B; BLOOD GROUP LEWIS SYSTEM; BLOOD GROUP O; BLOOD GROUP TYPING; DIAGNOSTIC VALUE; ERYTHROCYTE; FLOW CYTOMETRY; FLUORESCENCE ANALYSIS; GENOTYPE; HEMAGGLUTINATION; HOMOZYGOSITY; HUMAN; INTERMETHOD COMPARISON; NORMAL HUMAN; POINT MUTATION; PRIORITY JOURNAL;

EID: 0033368993     PISSN: 00429007     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1423-0410.1999.7740227.x     Document Type: Article

References (39)

1. Henry S, Oriol R, Samuelsson B: Lewis histoblood group system and associated secretory phenotypes. Vox Sang 1995;69:166-182.
2. Schenkel-Brunner H: Human Blood Groups: Chemical and Biochemical Basis of Antigen Specificity. Wien, Springer, 1995.
3. Oriol R: ABO, Hh, Lewis and Secretion -Serology, Genetics and Tissue Distribution; In Blood Cell Biochemistry. New York, Plenum Press, 1995, vol 6: Molecular Basis of Major Human Blood Group Antigens (edited by Cartron JP, Rouger P), pp 37-73.
4. Mollicone R, Cailleau A, Oriol R: Molecular genetics of H, Se, Lewis and other fucosyltransferase genes. Transfus Clin Biol 1995; 4:235-242.
5. Kukowska-Latallo J, Larsen R, et al.: A cloned human cDNA determines expression of a mouse stage-specific embryonic antigen and the Lewis blood group α(1,3/1,4)fucosyltransferase. Genes Dev 1990;4:1288-1303.
6. Kelly RJ, Rouquier S, Giorgi D, et al: Sequence and expression of a candidate for the human Secretor blood group α(1,2)fucosyltransferase gene (FUT2) - Homozygosity for an enzyme-inactivating nonsense mutation commonly correlates with the nonsecretor phenotype. J Biol Chem 1995;270:4640-4649.
7. Elmgren A, Rydberg L, Larson G: Genotypic heterogeneity among Lewis negative individuals. Biochem Biophys Res Commun 1993;196: 515-520.
8. Nishihara S, Yazawa S, Iwasaki H, et al.: α(1,3/1,4)Fucosyltransferase (FucT-III) gene is inactivated by a single amino acid substitution in Lewis histo-blood type negative individuals. Biochem Biophys Res Commun 1993; 196:624-631.
9. Koda Y, Kimura H, Mekada E: Analysis of Lewis fucosyltransferase genes from the human gastric mucosa of Lewis-positive and Lewis-negative individuals. Blood 1993;82: 2915-2919.
10. Mollicone R, Reguigne I, Kelly RJ, et al: Molecular basis for Lewis α(1,3/1,4)fucosyltransferase gene deficiency (FUT3) found in Lewis-negative Indonesian pedigrees. J Biol Chem 1994;269:20987-20994.
11. Nishihara S, Narimatsu H, Iwasaki H, et al: Molecular genetic analysis of the human Lewis histo-blood group system. J Biol Chem 1994;269:29271-29278.
12. Elmgren A, Börjeson C, Svensson L, et al: DNA sequencing and screening for point mutations in the human Lewis (FUT3) gene enables molecular gentoyping of the human Lewis blood group system. Vox Sang 1996;70: 97-103.
13. Yu LC, Yang YH, Broadberry RE, et al: Correlation of a misscnse mutation in the human Secretor α1,2fucosyltransferase gene with the Lewis(a+b+) phenotype: A potential molecular basis for the weak Secretor allele (Se-W). Biochem J 1995;312:329-332.
14. Henry S, Mollicone R, Lowe JB, et al: A second non secretor allele of the blood group α(1,2)fucosyltransferase gene (FUT2). Vox Sang 1996;70:21-25.
15. Yu LC, Broadberry RE, Yang YH, et al: Heterogeneity of the human Secretor α(1, 2)fucosyltransferase gene among Lewis (a+b-) non secretors. Biochem Biophys Res Commun 1996;222:390-394.
16. Henry S, Mollicone R, Fernandez P, et al: Molecular basis for erythrocyte Le(a+b+) and salivary ABH partial-secretor phenotypes. Expression of a FUT2 secretor allele with an A→T mutation at nucelotide 385 correlates with reduced α(1,2)fucosyltransferase activity. Glycoconj J 1996;13:985-993.
17. Ørntoft TF, Vestergaard EM, Holmes E, et al: Influence of Lewis α1-3/4-L-fucosyltransferase (FUT3) gene mutations on enzyme activity, erythrocyte phenotyping, and circulating tumor marker sialyl-Lewis a levels. J Biol Chem 1996;271:32260-32268.
18. Elmgren A, Mollicone R, Costache M, et al: Significance of individual point mutations, T202C and C314T, in the human Lewis (FUT3) gene for expression of Lewis antigens by human α(1,3/1,4)fucosyltransferase, FUCTIII. J Biol Chem 1997;272:21994-21998.
19. Narimatsu H, Iwasaki H, Nakayama F, et al: Lewis and secretor gene dosage affect CA 19-9 and Du-PAN-2 serum levels in normal individuals and coloreetal patients. Cancer Res 1998; 58:512-518.
20. Sneath J, Sneath P: Transformation of the Lewis groups of human red cells. Nature 1955; 176:172.
21. Marcus D, Cass L: Glycosphingolipids with Lewis blood group activity: Uptake by human erythrocytes. Science 1969;164:533-555.
22. b-active glycolipid in serum of pregnant women. Vox Sang 1981;40:27-33.
23. Langkilde NC, Wolf H, Ørntoft TF: Lewis antigen expression in benign and malignant tissues from RBC Le(a-b-) cancer patients. Br J Haematol 1991;79:493-499.
24. Stigendal L, Olsson R, Rydberg L, Samuelsson BE: Blood group Lewis phenotype on erythrocytes and in saliva in alcoholic pancreatitis and chronic liver disease. J Clin Pathol 1984;37: 778-782.
25. Karlsson K-A, Larson G: Structural characterization of lactotetraosylceramide, a novel glycosphingolipid isolated from human meconium. J Biol Chem 1979;254:9311-9316.
26. Kudo T, Iwasaki H, Nishihara S, et al: Molecular genetic analysis of the human Lewis histoblood group system. 2. Secretor gene inactivation by a novel single missense mutation A385T in Japanese non secretor individuals. J Biol Chem 1996;271:9830-9837.
27. b individuals. EurJ Biochem 1978;87:161-170.
28. Borén T, Falk P, Roth KA, et al: Attachment of Helicobacter pylori to human gastric epithelium mediated by blood group antigens. Science 1994;262:1892-1895.
29. Ilver D, Arnqvist A, Ögren J, et al: Helicobacter pylori adhesin binding fucosylated histoblood group antigens revealed by retagging. Science 1998;279:373-377.
30. Murai J, Naka K, Shimojo N, et al: Quantitative analysis of Lewis antigens on erythrocytes by flow cytometry. Clin Chim Acta 1994; 226:21-28.
31. Mollison P, Engelfriet C, Contreras M: In Blood Transfusion in Clinical Medicine, ed 10. Oxford, Blackwell Scientific Publications, 1997.
32. b antibodies. Vox Sang 1992;62:180-189.
33. Pisacka M, Stambergova M: Activation of Thomsen-Friedenreich antigens on red cells: A possible source of errors in antigen typing with some monoclonal antibodies. Vox Sang 1994;66:300.
34. Box GEP, Hunter WG, Hunter J: In Statistics for Experimenters. New York, Wiley, 1978.
35. Haaland PD: In Experimental Design in Biotechnology. New York, Dekker, 1989.
36. Karlsson KA: Preparation of total nonacid glycolipids for overlay analysis of receptors for bacteria and viruses and for other studies. Methods Enzymol 1987;138:212-220.
37. 125l-labeled toxin to thin-layer chromatograms. Anal Biochem 1981;109:399-402.
38. b blood group antigen. J Biol Chem 1981;256: 13223-13225.
39. Hansson GC, Karlsson KA, Larson G, et al: Detection of blood group type glycosphingolipid antigens on thin-layer plates using polyclonal antisera. J Immunol Methods 1985; 83:37-42.