Structural differences among monoclonal antibodies with distinct fine specificities and kinetic properties

Molecular Immunology

Volumn 36, Issue 17, 1999, Pages 1189-1205

  Lavoie, T B ^a   Mohan, S ^b   Lipschultz, C A ^b   Grivel, J C ^b   Li, Y ^b   Mainhart, C R ^b   Kam Morgan, L N W ^c   Drohan, W N ^d   Smith Gill, S J ^a,b  

^a UNIVERSITY OF MARYLAND   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

^c LABORATORY CORPORATION OF AMERICA   (United States)

^d Plasma Derivatives Laboratory   (United States)

Author keywords

Affinity maturation; Antibodies; Antigen binding; Antigen antibody interactions; Binding kinetics

Indexed keywords

AMINO ACID; ANTIGEN; EPITOPE; MONOCLONAL ANTIBODY;

AMINO ACID SEQUENCE; ANIMAL CELL; ANTIBODY STRUCTURE; ANTIGEN ANTIBODY REACTION; ANTIGEN BINDING; ANTIGEN RECOGNITION; ARTICLE; BINDING KINETICS; CROSS REACTION; DISSOCIATION; MOUSE; MULTIGENE FAMILY; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODY AFFINITY; ANTIBODY SPECIFICITY; ANTIGEN-ANTIBODY REACTIONS; EPITOPES; GENES, IMMUNOGLOBULIN; IMMUNOGLOBULIN HEAVY CHAINS; IMMUNOGLOBULIN VARIABLE REGION; KINETICS; MURAMIDASE; MUTAGENESIS, SITE-DIRECTED; VARIATION (GENETICS);

EID: 0033368120     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0161-5890(99)00130-3     Document Type: Article

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