Yeast as a model for human mtDNA replication

American Journal of Human Genetics

Volumn 65, Issue 5, 1999, Pages 1230-1237

  Shadel, Gerald S ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MITOCHONDRIAL DNA;

DNA REPLICATION; GENE MUTATION; GENETIC CONSERVATION; GENETIC MODEL; GENOME; HUMAN; MITOCHONDRION; MOLECULAR DYNAMICS; MOLECULAR STABILITY; NONHUMAN; PRIORITY JOURNAL; REVIEW; SACCHAROMYCES CEREVISIAE;

SACCHAROMYCES CEREVISIAE;

EID: 0033365008     PISSN: 00029297     EISSN: None     Source Type: Journal    
DOI: 10.1086/302630     Document Type: Article

References (40)

1. Baldacci G, Chérif-Zahar B, Bernardi G (1984) The initiation of DNA replication in the mitochondrial genome of yeast. EMBO J 3:2115-2120
2. Blanc H, Dujon B (1980) Replicator regions of the yeast mitochondrial DNA responsible for suppressiveness. Proc Natl Acad Sci USA 77:3942-3946
3. Bogenhagen DF (1999) Repair of mtDNA in vertebrates. Am J Hum Genet 64:1276-1281
4. Braithwaite D, Ito J (1993) Compilation, alignment, and phylogenetic relationships of DNA polymerases. Nucleic Acids Res 21:787-802
5. Clayton DA (1982) Replication of animal mitochondrial DNA. Cell 28:693-705
6. -(1991) Replication and transcription of vertebrate mitochondrial DNA. Annu Rev Cell Biol 7:453-478
7. Costanzo MC, Fox TD (1990) Control of mitochondrial gene expression in Saccharomyces cerevisiae. Annu Rev Genet 24: 91-113
8. de Zamaroczy M, Marotta R, Faugeron-Fonty G, Goursot R, Mangin M, Baldacci G, Bernardi G (1981) The origins of replication of the yeast mitochondrial genome and the phenomenon of suppressivity. Nature 292:75-78
9. Dieckmann CL, Staples RR (1994) Regulation of mitochondrial gene expression in Saccharomyces cerevisiae. Int Rev Cytol 152:145-181
10. -] mitochondrial DNA in Saccharomyces cerevisiae. Mol Cell Biol 10:10-15
11. Fangman WL, Henly JW, Churchill G, Brewer BJ (1989) Stable maintenance of a 35-base-pair yeast mitochondrial genome. Mol Cell Biol 9:1917-1921
12. Foury F (1989) Cloning and sequencing of the nuclear gene MIP1 encoding the catalytic subunit of the yeast mitochondrial DNA polymerase. J Biol Chem 264:20552-20560
13. Graves T, Dante M, Eisenhour L, Christianson TW (1998) Precise mapping and characterization of the RNA primers of DNA replication for a yeast hypersuppressive petite by in vitro capping with guanylyltransferase. Nucleic Acids Res 26:1309-1316
14. Greenleaf AL, Kelly JL, Lehman IR (1986) Yeast RPO41 gene product is required for transcription and maintenance of the mitochondrial genome. Proc Natl Acad Sci USA 83: 3391-3394
15. Grivell L (1995) Nucleo-mitochondrial interactions in mitochondrial gene expression. Crit Rev Biochem Mol Biol 30: 121-164
16. Grossman LI, Shoubridge KA (1996) Mitochondrial genetics and human disease. Bioessays 18:983-991
17. Hermann GJ, Shaw JM (1998) Mitochondrial dynamics in yeast. Annu Rev Cell Dev Biol 14:265-303
18. Holt IJ, Harding AE, Morgan-Hughes JA (1988) Deletions of muscle mitochondrial DNA in patients with mitochondrial myopathies. Nature 331:717-719
19. Howell N (1997) mtDNA recombination: what do in vitro data mean? Am J Hum Genet 61:19-22
20. Knight SAB, Kim R, Pain D, Dancis A (1999) The yeast connection to Friedreich ataxia. Am J Hum Genet 64:365-371
21. Larsson N, Clayton DA (1995) Molecular genetic aspects of human mitochondrial disorders. Annu Rev Genet 29: 151-178
22. Lee DY, Clayton DA (1998) Initiation of mitochondrial DNA replication by transcription and R-loop processing. J Biol Chem 273:30614-30621
23. Li K, Smagula CS, Parsons WJ, Richardson JA Gonzalez M, Hagler HK, Williams RS (1994) Subcellular partitioning of MRP RNA assessed by ultrastructural and biochemical analysis. J Cell Biol 124:871-882
24. Lisowsky T, Michaelis G (1988) A nuclear gene essential for mitochondrial replication suppresses a defect of mitochondrial transcription in Saccharomyces cerevisiae. Mol Gen Genet 214:218-223
25. Lockshon D, Zweifel SG, Freeman-Cook LL, Lorimer HE, Brewer BJ, Fangman WL (1995) A role for recombination junctions in the segregation of mitochondrial DNA in yeast. Cell 81:947-955
26. MacAlpine DM, Perlman PS, Butow RA (1998) The high-mobility group protein Abf2p influences the level of yeast mitochondrial DNA recombination intermediates in vivo. Proc Natl Acad Sci USA 95:6739-6743
27. Masters BS, Stohl LL, Clayton DA (1987) Yeast mitochondrial RNA polymerase is homologous to those encoded by bacteriophages T3 and T7. Cell 51:89-99
28. Myers AM, Pape LK, Tzagoloff A (1985) Mitochondrial protein synthesis is required for maintenance of intact mitochondrial genomes in Saccharomyces cerevisiae. EMBO J 4: 2087-2092
29. Parisi MA, Clayton DA (1991) Similarity of human mitochondrial transcription factor 1 to high mobility group proteins. Science 252:965-969
30. Poyton RO, McEwen JE (1996) Crosstalk between nuclear and mitochondrial genomes. Annu Rev Biochem 65:563-607
31. Reenan RA, Kolodner RD (1992) Characterization of insertion mutations in the Saccharomyces cerevisiae MSH1 and MSH2 genes: evidence for separate mitochondrial and nuclear functions. Genetics 132:975-985
32. Shadel GS, Clayton DA (1993) Mitochondrial transcription initiation: variation and conservation. J Biol Chem 268: 16083-16086
33. -(1997) Mitochondrial DNA maintenance in vertebrates. Annu Rev Biochem 66:409-435
34. Tiranti V, Savoia A, Forti F, D'Apolito M, Centra M, Rocchi M, Zeviani M (1997) Identification of the gene encoding the human mitochondrial RNA polymerase (hmtRPOL) by cyberscreening of the expressed sequence tags database. Hum Mol Genet 6:615-625
35. Van Dyck E, Clayton DA (1998) Transcription-dependent DNA transactions in the mitochondrial genome of a yeast hypersuppressive petite mutant. Mol Cell Biol 18: 2976-2985
36. Wallace DC (1992) Diseases of mitochondrial DNA. Annu Rev Biochem 61:1175-1212
37. Wallace DC, Singh G, Lott MT, Hodge JA, Schurr TG, Lezza AMS, Elsas LJ II, et al (1988) Mitochondrial DNA mutation associated with Leber's hereditary optic neuropathy. Science 242:1427-1430
38. Wang Y, Shadel GS (1999) Stability of the mitochondrial genome requires an amino-terminal domain of yeast mitochondrial RNA polymerase. Proc Natl Acad Sci USA 96: 8046-8051
39. Xu B, Clayton DA (1995) A persistent RNA-DNA hybrid is formed during transcription at a phylogenetically conserved mitochondrial DNA sequence. Mol Cell Biol 15:580-589
40. Yaffe MP (1999) The machinery of mitochondrial inheritance and behavior. Science 283:1493-1497