메뉴 건너뛰기




Volumn 65, Issue 5, 1999, Pages 1375-1386

Hypomethylation of an expanded FMR1 allele is not associated with a global DNA methylation defect

Author keywords

[No Author keywords available]

Indexed keywords

CELL DNA;

EID: 0033361880     PISSN: 00029297     EISSN: None     Source Type: Journal    
DOI: 10.1086/302628     Document Type: Article
Times cited : (17)

References (74)
  • 1
    • 0025970882 scopus 로고
    • Physical mapping across the fragile X: Hypermethylation and clinical expression of the fragile X syndrome
    • Bell MV, Hirst MC, Nakahori Y, MacKinnon RN, Roche A, Flint TJ, Jacobs PA, et al (1991) Physical mapping across the fragile X: hypermethylation and clinical expression of the fragile X syndrome. Cell 64:861-866
    • (1991) Cell , vol.64 , pp. 861-866
    • Bell, M.V.1    Hirst, M.C.2    Nakahori, Y.3    MacKinnon, R.N.4    Roche, A.5    Flint, T.J.6    Jacobs, P.A.7
  • 2
    • 0032126345 scopus 로고    scopus 로고
    • Cytosine methylation of repeated sequences in eukaryotes: The role of DNA pairing
    • Bender J (1998) Cytosine methylation of repeated sequences in eukaryotes: the role of DNA pairing. Trends Biochem Sci 23:252-256
    • (1998) Trends Biochem Sci , vol.23 , pp. 252-256
    • Bender, J.1
  • 3
    • 0030115772 scopus 로고    scopus 로고
    • Creation of genomic methylation patterns
    • Bestor TH, Tycko B (1996) Creation of genomic methylation patterns. Nat Genet 12:363-367
    • (1996) Nat Genet , vol.12 , pp. 363-367
    • Bestor, T.H.1    Tycko, B.2
  • 4
    • 85031585899 scopus 로고    scopus 로고
    • Fully expanded FMR1 CGG repeats exhibit a length-and differentiation-dependent instability in cell hybrids that is independent of DNA methylation
    • in press
    • Burman RW, Popovich BW, Jacky PB, Turker MS. Fully expanded FMR1 CGG repeats exhibit a length-and differentiation-dependent instability in cell hybrids that is independent of DNA methylation. Hum Mol Genet (in press)
    • Hum Mol Genet
    • Burman, R.W.1    Popovich, B.W.2    Jacky, P.B.3    Turker, M.S.4
  • 5
    • 0029008288 scopus 로고
    • Hairpins are formed by the single DNA strands of the fragile X triplet repeats: Structure and biological implications
    • Chen X, Mariappan SV, Catasti P, Ratliff R, Moyzis RK, Laayoun A, Smith SS, et al (1995) Hairpins are formed by the single DNA strands of the fragile X triplet repeats: structure and biological implications. Proc Natl Acad Sci USA 92: 5199-203
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 5199-5203
    • Chen, X.1    Mariappan, S.V.2    Catasti, P.3    Ratliff, R.4    Moyzis, R.K.5    Laayoun, A.6    Smith, S.S.7
  • 7
    • 0028340198 scopus 로고
    • Unstable triplets and their murational mechanism: Size reduction of the CGG repeat vs. germline mosaicism in the fragile X syndrome
    • Chiurazzi P, Kozak L, Neri G (1994) Unstable triplets and their murational mechanism: size reduction of the CGG repeat vs. germline mosaicism in the fragile X syndrome. Am J Med Genet 51:517-521
    • (1994) Am J Med Genet , vol.51 , pp. 517-521
    • Chiurazzi, P.1    Kozak, L.2    Neri, G.3
  • 8
    • 0032905253 scopus 로고    scopus 로고
    • Acetylated histones are associated with FMR1 in normal but not fragile X-syndrome cells
    • Coffee B, Zhang F, Warren ST, Reines D (1999) Acetylated histones are associated with FMR1 in normal but not fragile X-syndrome cells. Nat Genet 22:98-101
    • (1999) Nat Genet , vol.22 , pp. 98-101
    • Coffee, B.1    Zhang, F.2    Warren, S.T.3    Reines, D.4
  • 10
    • 16944362509 scopus 로고    scopus 로고
    • Screening and diagnosis for the fragile X syndrome among the mentally retarded: An epidemiological and psychological survey
    • Collaborative Fragile X Study Group
    • de Vries BB, van den Ouweland AM, Mohkamsing S, Duivenvoorden HJ, Mol E, Gelsema K, van Rijn M, et al (1997) Screening and diagnosis for the fragile X syndrome among the mentally retarded: an epidemiological and psychological survey. Collaborative Fragile X Study Group. Am J Hum Genet 61:660-667
    • (1997) Am J Hum Genet , vol.61 , pp. 660-667
    • De Vries, B.B.1    Van Den Ouweland, A.M.2    Mohkamsing, S.3    Duivenvoorden, H.J.4    Mol, E.5    Gelsema, K.6    Van Rijn, M.7
  • 11
    • 0027176361 scopus 로고
    • The FMR-1 protein is cytoplasmic, most abundant in neurons and appears normal in carriers of a fragile X premutation
    • Devys D, Lutz Y, Rouyer N, Bellocq JP, Mandel JL (1993) The FMR-1 protein is cytoplasmic, most abundant in neurons and appears normal in carriers of a fragile X premutation. Nat Genet 4:335-340
    • (1993) Nat Genet , vol.4 , pp. 335-340
    • Devys, D.1    Lutz, Y.2    Rouyer, N.3    Bellocq, J.P.4    Mandel, J.L.5
  • 12
    • 0030440796 scopus 로고    scopus 로고
    • Nuclease sensitivity of permeabilized cells confirms altered chromatin formation at the fragile X locus
    • Eberhart DE, Warren ST (1996) Nuclease sensitivity of permeabilized cells confirms altered chromatin formation at the fragile X locus. Somat Cell Mol Genet 22:435-441
    • (1996) Somat Cell Mol Genet , vol.22 , pp. 435-441
    • Eberhart, D.E.1    Warren, S.T.2
  • 14
    • 1842694302 scopus 로고
    • A general high-efficiency procedure for production of microcell hybrids
    • Fournier RE (1981) A general high-efficiency procedure for production of microcell hybrids. Proc Natl Acad Sci USA 78:6349-353
    • (1981) Proc Natl Acad Sci USA , vol.78 , pp. 6349-6353
    • Fournier, R.E.1
  • 15
    • 0026345716 scopus 로고
    • Variation of the CGG repeat at the fragile X site results in genetic instability: Resolution of the Sherman paradox
    • Fu YH, Kuhl DP, Pizzuti A, Pieretti M, Sutcliffe JS, Richards S, Verkerk AJ, et al (1991) Variation of the CGG repeat at the fragile X site results in genetic instability: resolution of the Sherman paradox. Cell 67:1047-1058
    • (1991) Cell , vol.67 , pp. 1047-1058
    • Fu, Y.H.1    Kuhl, D.P.2    Pizzuti, A.3    Pieretti, M.4    Sutcliffe, J.S.5    Richards, S.6    Verkerk, A.J.7
  • 16
    • 0033612235 scopus 로고    scopus 로고
    • Mitotic behavior of expanded CGG repeats studied on cultured cells: Further evidence for methylation-mediated triplet repeat stability in fragile X syndrome
    • Glaser D, Wohrle D, Salat U, Vogel W, Steinbach P (1999) Mitotic behavior of expanded CGG repeats studied on cultured cells: further evidence for methylation-mediated triplet repeat stability in fragile X syndrome [letter]. Am J Med Genet 84:226-228
    • (1999) Am J Med Genet , vol.84 , pp. 226-228
    • Glaser, D.1    Wohrle, D.2    Salat, U.3    Vogel, W.4    Steinbach, P.5
  • 17
    • 0029744342 scopus 로고    scopus 로고
    • Nucleosome assembly on methylated CGG triplet repeats in the fragile X mental retardation gene 1 promoter
    • Godde JS, Kass SU, Hirst MC, Wolffe AP (1996) Nucleosome assembly on methylated CGG triplet repeats in the fragile X mental retardation gene 1 promoter. J Biol Chem 271: 24325-24328
    • (1996) J Biol Chem , vol.271 , pp. 24325-24328
    • Godde, J.S.1    Kass, S.U.2    Hirst, M.C.3    Wolffe, A.P.4
  • 18
    • 0028264043 scopus 로고
    • High functioning fragile X males: Demonstration of an unmethylated fully expanded FMR-1 mutation associated with protein expression
    • Hagerman RJ, Hull CE, Safanda JF, Carpenter I, Staley LW, O'Connor RA, Seydel C, et al (1994) High functioning fragile X males: demonstration of an unmethylated fully expanded FMR-1 mutation associated with protein expression. Am J Med Genet 51:298-308
    • (1994) Am J Med Genet , vol.51 , pp. 298-308
    • Hagerman, R.J.1    Hull, C.E.2    Safanda, J.F.3    Carpenter, I.4    Staley, L.W.5    O'Connor, R.A.6    Seydel, C.7
  • 19
    • 0030732314 scopus 로고    scopus 로고
    • Fragile X syndrome and deletions in FMR1: New case and review of the literature
    • Hammond LS, Macias MM, Tarleton JC, Shashidhar Pai G (1997) Fragile X syndrome and deletions in FMR1: new case and review of the literature. Am J Med Genet 72: 430-434
    • (1997) Am J Med Genet , vol.72 , pp. 430-434
    • Hammond, L.S.1    Macias, M.M.2    Tarleton, J.C.3    Shashidhar Pai, G.4
  • 20
    • 0030894828 scopus 로고    scopus 로고
    • A variable domain of delayed replication in FRAXA fragile X chromosomes: X inactivation-like spread of late replication
    • Hansen RS, Canfield TK, Fjeld AD, Mumm S, Laird CD, Gartler SM (1997) A variable domain of delayed replication in FRAXA fragile X chromosomes: X inactivation-like spread of late replication. Proc Natl Acad Sci USA 94:4587-4592
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 4587-4592
    • Hansen, R.S.1    Canfield, T.K.2    Fjeld, A.D.3    Mumm, S.4    Laird, C.D.5    Gartler, S.M.6
  • 22
    • 0025760752 scopus 로고
    • Isolation of sequences that span the fragile X and identification of a fragile X-related CpG island
    • Heitz D, Rousseau F, Devys D, Saccone S, Abderrahim H, Le Paslier D, Cohen D, et al (1991) Isolation of sequences that span the fragile X and identification of a fragile X-related CpG island. Science 251:1236-1239
    • (1991) Science , vol.251 , pp. 1236-1239
    • Heitz, D.1    Rousseau, F.2    Devys, D.3    Saccone, S.4    Abderrahim, H.5    Le Paslier, D.6    Cohen, D.7
  • 24
    • 0027377155 scopus 로고
    • High resolution methylation analysis of the FMR1 gene trinucleotide repeat region in fragile X syndrome
    • Hornstra IK, Nelson DL, Warren ST, Yang TP (1993) High resolution methylation analysis of the FMR1 gene trinucleotide repeat region in fragile X syndrome. Hum Mol Genet 2:1659-1665
    • (1993) Hum Mol Genet , vol.2 , pp. 1659-1665
    • Hornstra, I.K.1    Nelson, D.L.2    Warren, S.T.3    Yang, T.P.4
  • 26
    • 0030743612 scopus 로고    scopus 로고
    • DNA methylation and imprinting: Why bother?
    • Jaenisch R (1997) DNA methylation and imprinting: why bother? Trends Genet 13:323-329
    • (1997) Trends Genet , vol.13 , pp. 323-329
    • Jaenisch, R.1
  • 27
    • 2642622566 scopus 로고    scopus 로고
    • The DNA methylation locus DDM1 is required for maintenance of gene silencing in Arabidopsis
    • Jeddeloh JA, Bender J, Richards EJ (1998) The DNA methylation locus DDM1 is required for maintenance of gene silencing in Arabidopsis. Genes Dev 12:1714-1725
    • (1998) Genes Dev , vol.12 , pp. 1714-1725
    • Jeddeloh, J.A.1    Bender, J.2    Richards, E.J.3
  • 28
    • 0032907728 scopus 로고    scopus 로고
    • Maintenance of genomic methylation requires a SWI2/SNF2-like protein
    • see comments
    • Jeddeloh JA, Stokes TL, Richards EJ (1999) Maintenance of genomic methylation requires a SWI2/SNF2-like protein [see comments]. Nat Genet 22:94-97
    • (1999) Nat Genet , vol.22 , pp. 94-97
    • Jeddeloh, J.A.1    Stokes, T.L.2    Richards, E.J.3
  • 30
    • 0027474543 scopus 로고
    • DNA methylation in the Alu sequences of diploid and haploid primary human cells
    • Kochanek S, Renz D, Doerfler W (1993) DNA methylation in the Alu sequences of diploid and haploid primary human cells. EMBO J 12:1141-1151
    • (1993) EMBO J , vol.12 , pp. 1141-1151
    • Kochanek, S.1    Renz, D.2    Doerfler, W.3
  • 31
    • 0025800165 scopus 로고
    • Mapping of DNA instability at the fragile X to a trinucleotide repeat sequence p(CCG)n
    • Kremer EJ, Pritchard M, Lynch M, Yu S, Holman K, Baker E, Warren ST, et al (1991) Mapping of DNA instability at the fragile X to a trinucleotide repeat sequence p(CCG)n. Science 252:1711-1714
    • (1991) Science , vol.252 , pp. 1711-1714
    • Kremer, E.J.1    Pritchard, M.2    Lynch, M.3    Yu, S.4    Holman, K.5    Baker, E.6    Warren, S.T.7
  • 32
    • 0029984825 scopus 로고    scopus 로고
    • A fragile X male with a broad smear on southern blot analysis representing 100-500 CGG repeats and no methylation at the EagI site of the FMR-1 gene
    • Lachiewicz AM, Spiridigliozzi GA, McConkie-Rosell A, Burgess D, Feng Y, Warren ST, Tarleton J (1996) A fragile X male with a broad smear on Southern blot analysis representing 100-500 CGG repeats and no methylation at the EagI site of the FMR-1 gene. Am J Med Genet 64:278-282
    • (1996) Am J Med Genet , vol.64 , pp. 278-282
    • Lachiewicz, A.M.1    Spiridigliozzi, G.A.2    McConkie-Rosell, A.3    Burgess, D.4    Feng, Y.5    Warren, S.T.6    Tarleton, J.7
  • 33
    • 0027251502 scopus 로고
    • Proposed roles for DNA methylation in Alu transcriptional repression and mutational inactivation
    • Liu WM, Schmid CW (1993) Proposed roles for DNA methylation in Alu transcriptional repression and mutational inactivation. Nucleic Acids Res 21:1351-1359
    • (1993) Nucleic Acids Res , vol.21 , pp. 1351-1359
    • Liu, W.M.1    Schmid, C.W.2
  • 35
    • 0027434212 scopus 로고
    • DNA methylation of the fragile X locus in somatic and germ cells during fetal development: Relevance to the fragile X syndrome and X inactivation
    • Luo S, Robinson JC, Reiss AL, Migeon BR (1993) DNA methylation of the fragile X locus in somatic and germ cells during fetal development: relevance to the fragile X syndrome and X inactivation. Somat Cell Mol Genet 19:393-404
    • (1993) Somat Cell Mol Genet , vol.19 , pp. 393-404
    • Luo, S.1    Robinson, J.C.2    Reiss, A.L.3    Migeon, B.R.4
  • 39
    • 0030969206 scopus 로고    scopus 로고
    • Alpha-satellite DNA methylation in normal individuals and in ICF patients; heterogeneous methylation of constitutive heterochromatin in adult and fetal tissues
    • Miniou P, Jeanpierre M, Bourc'his D, Coutinho Barbosa AC, Blanquet V, Viegas-Pequignot E (1997b) alpha-satellite DNA methylation in normal individuals and in ICF patients; heterogeneous methylation of constitutive heterochromatin in adult and fetal tissues. Hum Genet 99:738-745
    • (1997) Hum Genet , vol.99 , pp. 738-745
    • Miniou, P.1    Jeanpierre, M.2    Bourc'his, D.3    Coutinho Barbosa, A.C.4    Blanquet, V.5    Viegas-Pequignot, E.6
  • 41
    • 0027525976 scopus 로고
    • A cis-acting element accounts for a conserved methylation pattern up-stream of the mouse adenine phosphoribosyltransferase gene
    • Mummaneni P, Bishop PL, Turker MS (1993) A cis-acting element accounts for a conserved methylation pattern up-stream of the mouse adenine phosphoribosyltransferase gene. J Biol Chem 268:552-558
    • (1993) J Biol Chem , vol.268 , pp. 552-558
    • Mummaneni, P.1    Bishop, P.L.2    Turker, M.S.3
  • 42
    • 0028939394 scopus 로고
    • Epigenetic gene inactivation induced by a cis-acting methylation center
    • Mummaneni P, Walker KA, Bishop PL, Turker MS (1995) Epigenetic gene inactivation induced by a cis-acting methylation center. J Biol Chem 270:788-792
    • (1995) J Biol Chem , vol.270 , pp. 788-792
    • Mummaneni, P.1    Walker, K.A.2    Bishop, P.L.3    Turker, M.S.4
  • 43
    • 0026339303 scopus 로고
    • Instability of a 550-base pair DNA segment and abnormal methylation in fragile X syndrome
    • Oberle I, Rousseau F, Heitz D, Kretz C, Devys D, Hanauer A, Boue J, et al (1991) Instability of a 550-base pair DNA segment and abnormal methylation in fragile X syndrome. Science 252:1097-1102
    • (1991) Science , vol.252 , pp. 1097-1102
    • Oberle, I.1    Rousseau, F.2    Heitz, D.3    Kretz, C.4    Devys, D.5    Hanauer, A.6    Boue, J.7
  • 45
    • 0028141919 scopus 로고
    • A multicenter study on genotype-phenotype correlations in the fragile X syndrome, using direct diagnosis with probe StB12.3: The first 2,253 cases
    • Rousseau F, Heitz D, Tarleton J, MacPherson J, Malmgren H, Dahl N, Barnicoat A, et al (1994a) A multicenter study on genotype-phenotype correlations in the fragile X syndrome, using direct diagnosis with probe StB12.3: the first 2,253 cases. Am J Hum Genet 55:225-237
    • (1994) Am J Hum Genet , vol.55 , pp. 225-237
    • Rousseau, F.1    Heitz, D.2    Tarleton, J.3    MacPherson, J.4    Malmgren, H.5    Dahl, N.6    Barnicoat, A.7
  • 46
    • 0028305242 scopus 로고
    • No mental retardation in a man with 40% abnormal methylation at the FMR-1 locus and transmission of sperm cell mutations as premutations
    • Rousseau F, Robb LJ, Rouillard P, Der Kaloustian VM (1994b) No mental retardation in a man with 40% abnormal methylation at the FMR-1 locus and transmission of sperm cell mutations as premutations. Hum Mol Genet 3:927-930
    • (1994) Hum Mol Genet , vol.3 , pp. 927-930
    • Rousseau, F.1    Robb, L.J.2    Rouillard, P.3    Der Kaloustian, V.M.4
  • 47
    • 0029685023 scopus 로고    scopus 로고
    • Alu: Structure, origin, evolution, significance and function of one-tenth of human DNA
    • Schmid CW (1996) Alu: structure, origin, evolution, significance and function of one-tenth of human DNA. Prog Nucleic Acid Res Mol Biol 53:283-319
    • (1996) Prog Nucleic Acid Res Mol Biol , vol.53 , pp. 283-319
    • Schmid, C.W.1
  • 48
    • 0026055006 scopus 로고
    • Human Alu subfamilies and their methylation revealed by blot hybridization
    • -(1991) Human Alu subfamilies and their methylation revealed by blot hybridization. Nucleic Acids Res 19: 5613-5617
    • (1991) Nucleic Acids Res , vol.19 , pp. 5613-5617
  • 49
    • 0028829566 scopus 로고
    • DNA, FISH and complementation studies in ICF syndrome: DNA hypomethylation of repetitive and single copy loci and evidence for a trans acting factor
    • Schuffenhauer S, Bartsch O, Stumm M, Buchholz T, Petropoulou T, Kraft S, Belohradsky B, et al (1995) DNA, FISH and complementation studies in ICF syndrome: DNA hypomethylation of repetitive and single copy loci and evidence for a trans acting factor. Hum Genet 96:562-571
    • (1995) Hum Genet , vol.96 , pp. 562-571
    • Schuffenhauer, S.1    Bartsch, O.2    Stumm, M.3    Buchholz, T.4    Petropoulou, T.5    Kraft, S.6    Belohradsky, B.7
  • 50
    • 0033612240 scopus 로고    scopus 로고
    • In vivo footprinting analysis of the FMR1 gene: Proposals concerning gene regulation in high-functioning males
    • Schwemmle S (1999) In vivo footprinting analysis of the FMR1 gene: proposals concerning gene regulation in high-functioning males [letter]. Am J Med Genet 84:266-267
    • (1999) Am J Med Genet , vol.84 , pp. 266-267
    • Schwemmle, S.1
  • 52
    • 0033070196 scopus 로고    scopus 로고
    • Biological implications of the DNA structures associated with disease-causing triplet repeats
    • Sinden RR (1999) Biological implications of the DNA structures associated with disease-causing triplet repeats. Am J Hum Genet 64:346-353
    • (1999) Am J Hum Genet , vol.64 , pp. 346-353
    • Sinden, R.R.1
  • 53
    • 0027327486 scopus 로고
    • The protein product of the fragile X gene, FMR1, has characteristics of an RNA-binding protein
    • Siomi H, Siomi MC, Nussbaum RL, Dreyfuss G (1993) The protein product of the fragile X gene, FMR1, has characteristics of an RNA-binding protein. Cell 74:291-298
    • (1993) Cell , vol.74 , pp. 291-298
    • Siomi, H.1    Siomi, M.C.2    Nussbaum, R.L.3    Dreyfuss, G.4
  • 55
    • 0030479536 scopus 로고    scopus 로고
    • The origin of interspersed repeats in the human genome
    • Smit AF (1996) The origin of interspersed repeats in the human genome. Curr Opin Genet Dev 6:743-748
    • (1996) Curr Opin Genet Dev , vol.6 , pp. 743-748
    • Smit, A.F.1
  • 56
  • 57
    • 0011078712 scopus 로고
    • De novo methylation, expression, and infectivity of retroviral genomes introduced into embryonal carcinoma cells
    • Stewart CL, Stuhlmann H, Jahner D, Jaenisch R (1982) De novo methylation, expression, and infectivity of retroviral genomes introduced into embryonal carcinoma cells. Proc Natl Acad Sci USA 79:4098-4102
    • (1982) Proc Natl Acad Sci USA , vol.79 , pp. 4098-4102
    • Stewart, C.L.1    Stuhlmann, H.2    Jahner, D.3    Jaenisch, R.4
  • 58
    • 0031981857 scopus 로고    scopus 로고
    • Dependence of McrBC cleavage on distance between recognition elements
    • Stewart FJ, Raleigh EA (1998) Dependence of McrBC cleavage on distance between recognition elements. Biol Chem 379: 611-616
    • (1998) Biol Chem , vol.379 , pp. 611-616
    • Stewart, F.J.1    Raleigh, E.A.2
  • 59
    • 0030785355 scopus 로고    scopus 로고
    • Epigenetic variation illustrated by DNA methylation patterns of the fragile-X gene FMR1
    • Stoger R, Kajimura TM, Brown WT, Laird CD (1997) Epigenetic variation illustrated by DNA methylation patterns of the fragile-X gene FMR1. Hum Mol Genet 6:1791-1801
    • (1997) Hum Mol Genet , vol.6 , pp. 1791-1801
    • Stoger, R.1    Kajimura, T.M.2    Brown, W.T.3    Laird, C.D.4
  • 60
    • 0001920056 scopus 로고    scopus 로고
    • Using DNA fragments as probes
    • Ausubel FM, Brent R, Kingston RE, Moore DD, Seidman JG, Smith JA, Struhl K, et al (eds). John Wiley & Sons, New York
    • Strauss WM (1998) Using DNA fragments as probes. In: Ausubel FM, Brent R, Kingston RE, Moore DD, Seidman JG, Smith JA, Struhl K, et al (eds) Current protocols in molecular biology. Vol 1. John Wiley & Sons, New York, pp 6.3.1-6.3.6
    • (1998) Current Protocols in Molecular Biology , vol.1 , pp. 631-636
    • Strauss, W.M.1
  • 63
    • 0025851721 scopus 로고
    • Region-and cell type-specific de novo DNA methylation in cultured mammalian cells
    • Turker MS, Mummaneni P, Bishop PL (1991) Region-and cell type-specific de novo DNA methylation in cultured mammalian cells. Somat Cell Mol Genet 17:151-157
    • (1991) Somat Cell Mol Genet , vol.17 , pp. 151-157
    • Turker, M.S.1    Mummaneni, P.2    Bishop, P.L.3
  • 64
    • 0024638848 scopus 로고
    • Allelic variation linked to adenine phosphoribosyltransferase locus in mouse teratocarcinoma cell line and feral-derived mouse strains
    • Turker MS, Stambrook PJ, Tischfield JA, Smith AC, Martin GM (1989a) Allelic variation linked to adenine phosphoribosyltransferase locus in mouse teratocarcinoma cell line and feral-derived mouse strains. Somat Cell Mol Genet 15: 159-166
    • (1989) Somat Cell Mol Genet , vol.15 , pp. 159-166
    • Turker, M.S.1    Stambrook, P.J.2    Tischfield, J.A.3    Smith, A.C.4    Martin, G.M.5
  • 65
    • 0024405205 scopus 로고
    • A partial methylation profile for a CpG site is stably maintained in mammalian tissues and cultured cell lines
    • Turker MS, Swisshelm K, Smith AC, Martin GM (1989b) A partial methylation profile for a CpG site is stably maintained in mammalian tissues and cultured cell lines. J Biol Chem 264:11632-11636
    • (1989) J Biol Chem , vol.264 , pp. 11632-11636
    • Turker, M.S.1    Swisshelm, K.2    Smith, A.C.3    Martin, G.M.4
  • 67
    • 0025905795 scopus 로고
    • Identification of a gene (FMR-1) containing a CGG repeat coincident with a breakpoint cluster region exhibiting length variation in fragile X syndrome
    • Verkerk AJ, Pieretti M, Sutcliffe JS, Fu Y-H, Kuhl DP, Pizzuti A, Reiner O, et al (1991) Identification of a gene (FMR-1) containing a CGG repeat coincident with a breakpoint cluster region exhibiting length variation in fragile X syndrome. Cell 65:905-914
    • (1991) Cell , vol.65 , pp. 905-914
    • Verkerk, A.J.1    Pieretti, M.2    Sutcliffe, J.S.3    Fu, Y.-H.4    Kuhl, D.P.5    Pizzuti, A.6    Reiner, O.7
  • 69
    • 0029790784 scopus 로고    scopus 로고
    • Methylation of expanded CCG triplet repeat DNA from fragile X syndrome patients enhances nucleosome exclusion
    • Wang YH, Griffith J (1996) Methylation of expanded CCG triplet repeat DNA from fragile X syndrome patients enhances nucleosome exclusion. J Biol Chem 271:22937-22940
    • (1996) J Biol Chem , vol.271 , pp. 22937-22940
    • Wang, Y.H.1    Griffith, J.2
  • 70
    • 0029921704 scopus 로고    scopus 로고
    • FMR1 fully expanded mutation with minimal methylation in a high functioning fragile X male
    • see comments
    • Wang Z, Taylor AK, Bridge JA (1996) FMR1 fully expanded mutation with minimal methylation in a high functioning fragile X male [see comments]. J Med Genet 33:376-378
    • (1996) J Med Genet , vol.33 , pp. 376-378
    • Wang, Z.1    Taylor, A.K.2    Bridge, J.A.3
  • 71
    • 0031971691 scopus 로고    scopus 로고
    • Unusual mutations in high functioning fragile X males: Apparent instability of expanded unmethylated CGG repeats
    • Wohrle D, Salat U, Glaser D, Mucke J, Meisel-Stosiek M, Schindler D, Vogel W, et al (1998) Unusual mutations in high functioning fragile X males: apparent instability of expanded unmethylated CGG repeats. J Med Genet 35: 103-111
    • (1998) J Med Genet , vol.35 , pp. 103-111
    • Wohrle, D.1    Salat, U.2    Glaser, D.3    Mucke, J.4    Meisel-Stosiek, M.5    Schindler, D.6    Vogel, W.7
  • 72
    • 0030576353 scopus 로고    scopus 로고
    • DNA methylation and triplet repeat stability: New proposals addressing actual questions on the CGG repeat of fragile X syndrome
    • Wohrle D, Schwemmle S, Steinbach P (1996) DNA methylation and triplet repeat stability: new proposals addressing actual questions on the CGG repeat of fragile X syndrome [letter]. Am J Med Genet 64:266-267
    • (1996) Am J Med Genet , vol.64 , pp. 266-267
    • Wohrle, D.1    Schwemmle, S.2    Steinbach, P.3
  • 73
    • 0030840954 scopus 로고    scopus 로고
    • Cytosine methylation and the ecology of intragenomic parasites
    • see comments
    • Yoder JA, Walsh CP, Bestor TH (1997) Cytosine methylation and the ecology of intragenomic parasites [see comments]. Trends Genet 13:335-340
    • (1997) Trends Genet , vol.13 , pp. 335-340
    • Yoder, J.A.1    Walsh, C.P.2    Bestor, T.H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.