Effect of multiple doses of montelukast, a CysLT1 receptor antagonist, on digoxin pharmacokinetics in healthy volunteers

Journal of Clinical Pharmacology

Volumn 39, Issue 9, 1999, Pages 941-944

  Depre, M ^a   Van Hecken, A ^a   Verbesselt, R ^a   Wynants, K ^a   De Lepeleire, I ^a   Freeman, A ^a   Holland, S ^a   Shahane, A ^a   Gertz, B ^a   De Schepper, P J ^a  

^a UNIVERSITY HOSPITALS LEUVEN   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

DIGOXIN; MONTELUKAST;

ADULT; AREA UNDER THE CURVE; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DOUBLE BLIND PROCEDURE; DRUG BLOOD LEVEL; DRUG EXCRETION; DRUG HALF LIFE; FEMALE; HUMAN; HUMAN EXPERIMENT; MALE; RADIOIMMUNOASSAY; RANDOMIZED CONTROLLED TRIAL; URINARY EXCRETION;

EID: 0033306834     PISSN: 00912700     EISSN: None     Source Type: Journal    
DOI: 10.1177/00912709922008579     Document Type: Article

References (14)

1. 4 receptor antagonist
2. 4-receptor antagonism in the airways of patients with asthma
3. 4) receptor antagonist, in patients with chronic asthma
4. Pharmacokinetics, bioavailibility, and safety of montelukast sodium (MK-0476) in healthy males and females
5. Pharmacokinetic interactions with digoxin
6. Pharmacokinetic interactions with digoxin and other drugs
7. 1 receptor antagonist, in human plasma and bile
8. Pharmacokinetics and bioavailibility of montelukast sodium (MK0476) in healthy young and elderly volunteers
9. Serum potassium and the electrocardiogram in hypokalemia
10. Effect of digitalis glucosides on the electrocardiogram and exercise test in healthy subjects
11. The effect of digitalis on the exercise electrocardiogram
12. Evaluation of digoxin bioavailibility in single dose studies
13. Effect of multiple doses of Losartan on the pharmacokinetics of single doses of digoxin in healthy volunteers
14. Intersubject variation in absorption of digoxin in normal volunteers