Multiple changes in rate-determining step in the acid and base catalyzed cyclizations of ethyl N-(p-nitrophenyl)hydantoates caused by methyl substitution

Canadian Journal of Chemistry

Volumn 77, Issue 5-6, 1999, Pages 849-859

  Blagoeva, Iva B ^a   Kirby, Anthony J ^b   Koedjikov, Asen H ^a   Pojarlieff, Ivan G ^a  

^a INSTITUTE OF ORGANIC CHEMISTRY   (Bulgaria)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Gem dimethyl effect; General base catalysis; Mechanism; Proton transfer; Steric hindrance

Indexed keywords

AMINO ACID DERIVATIVE; ESTER; METHYL GROUP;

ARTICLE; CATALYSIS; CHEMICAL REACTION; CYCLIZATION; KINETICS; PH; PROTON TRANSPORT;

CATALYSIS; PROTONATION;

ACID CATALYSIS; BASE CATALYZED; CYCLIZATIONS; FIRST ORDER; GEM-DIMETHYL; GEM-DIMETHYL EFFECT; GENERAL BASE; GENERAL BASE CATALYSIS; HIGH PH; STERIC HINDRANCES;

CYCLIZATION;

EID: 0033306510     PISSN: 00084042     EISSN: None     Source Type: Journal    
DOI: 10.1139/v99-079     Document Type: Article

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