Salmonella landau as a live vaccine against Escherichia coli O157:H7 investigated in a mouse model of intestinal colonization

Canadian Journal of Microbiology

Volumn 45, Issue 9, 1999, Pages 723-731

  Conlan, J Wayne ^a   KuoLee, Rhonda ^a   Webb, Ann ^a   Perry, Malcolm B ^a  

^a NATIONAL RESEARCH COUNCIL CANADA   (Canada)

Author keywords

Escherichia coli O157:H7; Mice; Mucosal immunity; Salmonella Landau

Indexed keywords

ANTIBODY; ANTIGEN; ESCHERICHIA COLI VACCINE; LIVE VACCINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY TITER; ARTICLE; BACTERIAL COLONIZATION; CONTROLLED STUDY; ESCHERICHIA COLI; FEMALE; HOST RESISTANCE; HUMORAL IMMUNITY; IMMUNE STATUS; INFECTION PREVENTION; INTESTINE INFECTION; MOUSE; MUCOSAL IMMUNITY; NONHUMAN; PRIORITY JOURNAL; SALMONELLA;

ANIMALIA; BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; NEGIBACTERIA; SALMONELLA;

EID: 0033306436     PISSN: 00084166     EISSN: None     Source Type: Journal    
DOI: 10.1139/w99-059     Document Type: Article

References (27)

1. Bundle, D.R., Gerken, M., and Perry, M.B. 1985. Two-dimensional nuclear magnetic resonance at 500MHz: the structural elucidation of a Salmonella serogroup N polysaccharide antigen. Can. J. Chem. 64: 255-264.
2. Carter, P.B., and Collins, F.M. 1974. The route of enteric infection in normal mice. J. Exp. Med. 139: 1189-1203.
3. Conlan, J.W., and Perry, M.B. 1998. Susceptibility of three strains of conventional adult mice to intestinal colonization by an isolate of Escherichia coli O157:H7. Can. J. Microbiol. 44: 800-805.
4. Conlan, J.W., Cox, A.D., KuoLee, R., Webb, A., and Perry, M.B. 1999. Parenteral immunization with a glyco-conjugate vaccine containing the O157 antigen of Escherichia coli O157:H7 elicits a systemic humoral immune response in mice, but fails to prevent colonization by the pathogen. Can. J. Microbiol. 45: 279-286.
5. Curtiss, R. 1990. Attenuated Salmonella strains as live vectors for the expression of foreign antigens. In New generation vaccines. Edited by G.C. Woodrow and M.M. Levine. Marcel Dekker, New York. pp. 161-188.
6. Diez-Gonzalez, F., Callaway, T.R., Kizoulis, M.G., and Russell, J.B. 1998. Grain feeding and the dissemination of acid-resistant Escherichia coli from cattle. Science (Washington, D.C.), 281: 1666-1668.
7. Elson, C.O., Eadling, W., and Lefkowitz, J. 1984. A lavage technique allowing repeated measurement of IgA antibody in mouse intestinal secretions. J. Immunol. Methods, 67: 101-108.
8. Fujii, J., Kita, T., Yoshida, S-I, Takeda, T., Kobayashi, H., Tanaka, N., Ohsato, K., and Mizuguchi, Y. 1994. Direct evidence of neuron impairment by oral infection with verotoxin-producing Escherichia coli O157:H7 in mitomycin-treated mice. Infect. Immun. 62: 3447-3453.
9. Hackett, J. 1990. Salmonella-based vaccines. Vaccine, 8: 5-11.
10. Hancock, D.D., Besser, T.E., and Rice, D.H. 1998. Ecology of Escherichia coli O157:H7 in cattle and management practices. In Escherichia coli O157:H7 and other shiga toxin-producing E. coli. Edited by J.B. Kaper and A.D. O'Brien. American Society for Microbiology, Washington, D.C. pp. 85-91.
11. Jackson, R.J., Fujihashi, K., Amano, J.X., Kiyono, H., Elson, C.O., and McGhee, J.R. 1993. Optimizing oral vaccines: induction of systemic and mucosal B-cell and antibody responses to tetanus toxoid by use of cholera toxin B-subunit whole-cell vaccine. Infect. Immun. 62: 3594-3597.
12. James, S.P., and Klapproth, J.M. 1996. Major pathways of mucosal immunity and inflammation: cell activation, cytokine production, and role of bacterial factors. Aliment. Pharmacol. Ther. 10(2): 1-8.
13. Karpman, D., Connel, H., Svennson, M., Scheutz, F., Alm, P., and Svanborg, C. 1997. The role of lipopolysaccharide and shiga-like toxin in a mouse model of Escherichia coli O157:H7 infection. J. Infect. Dis. 175: 611-620.
14. Konadu, E., Robbins, J.B., Shiloach, J., Bryla, D.A., and Szu, S.C. 1994. Preparation, characterization, and immunological properties in mice of Escherichia coli O157 O-specific polysaccharide-protein conjugate vaccines. Infect. Immun. 62: 5048-5054.
15. Konadu, E.Y., Parke, J.C., Tran, H.T., Bryla, D.A., Robbins, J.B., and Szu, S.C. 1998. Investigational vaccine for Escherichia coli O157: phase 1 study of O157 O-specific polysaccharide Pseudomonas aeruginosa recombinanat exoprotein A (rEPA) conjugates in adults. J. Infect. Dis. 177: 383-387.
16. McGhee, J.R., and Kiyono, H. 1994. Effective mucosal immunity: current concepts for vaccine delivery and immune response analysis. Int. J. Technol. Assess. Health Care, 10: 93-106.
17. Michetti, P., Mahan, M.J., Slauch, J.M., Mekalanos, J.J., and Neutra, M.R. 1992. Monoclonal secretory immunoglobulin A protects mice against oral challenge with the invasive pathogen Salmonella typhimurium. Infect Immun. 60: 1786-1792.
18. Miller, C.P., and Bohnhoff, M. 1963. Changes in the mouse's enteric microflora associated with enhanced susceptibility to Salmonella infection following streptomycin treatment. J. Infect. Dis. 113: 59-66.
19. Neill, M.A. 1994. Pathogenesis of Escherichia coli O157:H7 infection. Curr. Opin. Infect. Dis. 7: 295-303.
20. Neill, M.A. 1998. Treatment of disease due to shiga toxin-producing Escherichia coli: infectious disease management. In Escherichia coli O157:H7 and other shiga toxin-producing E. coli. Edited by J.B. Kaper and A.D. O'Brien. American Society for Microbiology, Washington, D.C. pp. 357-363.
21. Perry, M.B., MacLean, L., and Griffith, D.W. 1986. Structure of the O-chain polysaccharide of the phenol-phase soluble lipopolysaccharide of Escherichia coli O157:H7. Biochem. Cell Biol. 64: 21-28.
22. Perry, M.B., Bundle, D.R., Gidney, M.A.J., and Lior, H. 1988. Identification of Escherichia coli serotype O157 strains by using a monoclonal antibody. J. Clin. Microbiol. 26: 2391-2394.
23. Shalaby, W.S.W. 1995. Development of oral vaccines to stimulate mucosal and systemic immunity: barriers and novel strategies. Clin. Immunol. Immunopathol. 74: 127-134.
24. Su, C., and Brandt, L.J. 1995. Escherichia coli O157:H7 infection in humans. Ann. Intern. Med. 123: 698-714.
25. Wadolkowski, E.A., Sung, L.M., Burris, J.A., Samuel, J.E., and O'Brien, A.D. 1990. Acute renal tubular necrosis and death of mice orally infected with Esherichia coli strains that produce shiga-like toxin type II. Infect. Immun. 58: 3959-3965.
26. Winner, L., Mack, J., Welzin, R., Mekalanos, J.J., Kraehenbuhl, J.-P., and Neutra, M.R. 1991. New model for analysis of mucosal immunity: intestinal secretion of specific monoclonal immunoglobulin A from hybridoma tumors protects against Vibrio cholerae infection. Infect. Immun. 59: 977-982.
27. Zhao, T., Doyle, M.P., Harmon, B.G., Brown, C.A., Mueller, P.O.E., and Parks, A.H. 1998. Reduction of carriage of enterohemorrhagic Esherichia coli O157:H7 in cattle by inoculation with probiotic bacteria. J. Clin. Microbiol. 36: 641-647.