Evidence that the insulin-like growth factor binding protein-4 protease in human ovarian follicular fluid is pregnancy associated plasma protein-A

Journal of Clinical Endocrinology and Metabolism

Volumn 84, Issue 12, 1999, Pages 4742-4745

  Conover, Cheryl A ^a   Oxvig, Claus ^b   Overgaard, Michael T ^b   Christiansen, Michael ^c   Giudice, Linda C ^d  

^a MAYO CLINIC   (United States)

^b AARHUS UNIVERSITY   (Denmark)

^c STATENS SERUM INSTITUT   (Denmark)

^d STANFORD UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PREGNANCY ASSOCIATED PLASMA PROTEIN A; PROTEINASE; SOMATOMEDIN BINDING PROTEIN 4;

ARTICLE; ENZYME ACTIVITY; FEMALE; GRANULOSA CELL; HUMAN; NORMAL HUMAN; OVARY FOLLICLE; OVARY FOLLICLE DEVELOPMENT; OVARY FOLLICLE FLUID; PRIORITY JOURNAL; PROTEIN DEGRADATION;

EID: 0033305208     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jcem.84.12.6342     Document Type: Article

References (22)

1. The insulin-related ovarian regulatory system in health and disease
2. Identification and molecular characterization of insulin-like growth factor binding in proteins (IGFBP-1, -2, -3, -4, -5, and -6)
3. Physiological role of insulin-like-growth-factor-binding protein-4 in human folliculogenesis
4. Anatomy of the human ovarian insulin-like growth factor system
5. Expression of genes encoding the insulin-like growth factors (IGF-I and IGF-II), IGF and insulin receptors, and IGF-binding proteins- 1-6 and the localization of their gene products in normal and polycystic ovary syndrome ovaries
6. Insulin-like growth factor binding protein profiles in human ovarian follicular fluid correlate with follicular functional status
7. Insulin-like growth factor-binding proteins in healthy and atretic follicles during natural menstrual cycles
8. Potent inhibition of human ovarian steroidogenesis by insulin-like growth factor binding protein-4 (IGFBP-4)
9. Estrogen- but not androgen-dominant human ovarian follicular fluid contains an insulin-like growth factor binding protein-4 protease
10. Effect of follicle stimulating hormone and insulin-like growth factors on proteolysis of insulin-like growth factor binding protein-4 in human granulosa cells
11. Interferon-γ and activin-A promote insulin-like growth factor binding protein-2 and -4 accumulation by human luteinizing granulosa cells, and interferon-γ promotes their apoptosis
12. The insulin-like growth factor (IGF)-dependent IGF binding protein-4 protease secreted by human fibroblasts is pregnancy-associated plasma protein-A
13. Hormonal correlates of follicular development in the human ovary
14. Regulation of insulin-like growth factor binding protein production by human luteinizing granulosa cells cultured in defined medium
15. Isolation and characterization of circulating complex between human pregnancy-associated plasma protein-A and proform of eosinophil major basic protein
16. Double-monoclonal immunofluorometric assays for pregnancy-associated plasma protein A/proeosinophil major basic protein (PAPP-A/proMBP) complex in first-trimester maternal serum screening for Down syndrome
17. Posttranslational regulation of insulin-like growth factor binding protein-4 in normal and transformed human fibroblasts: Insulin-like growth factor dependence and biological studies
18. Serum and follicular levels of insulin-like growth factor (IGF)-I, IGF-II, and IGF binding proteins-1 and -3 during the normal men-strual cycle
19. Regulation of insulin-like growth factor binding protein 4 by a specific insulin-like growth factor binding protein 4 proteinase in normal human osteoblast-like cells: Implications in bone cell physiology
20. Regulation of insulin-like growth factor (IGF)-binding protein-4 availability in normal human osteoblast-like cells: Role of endogenous IGFs
21. Hyperstimulated human preovulatory follicular fluid, luteinized cells of unruptured follicles, and corpus luteum contain pregnancy-associated plasma protein A (PAPP-A)