Destabilase complexes - Natural liposome produced by medicinal leeches Hirudo medicinalis

Fundamental and Clinical Pharmacology

Volumn 13, Issue 1, 1999, Pages 102-106

  Nikonov, Guennady I ^a,b   Titova, Elena A ^b  

^a BIORICA 245   (France)

^b Research Centre of BIOCON   (Ukraine)

Author keywords

6 Keto PGF(1 ); Destabilase; Hirudin; Liposome; Medicinal leech; Prostacyclin

Indexed keywords

DESTABILASE; HIRUDIN; KALLIKREIN INHIBITOR; LIPOSOME; PROSTACYCLIN DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG ISOLATION; DRUG MECHANISM; DRUG PENETRATION; DRUG STRUCTURE; HEMOSTASIS; LEECH; MALE; MICELLE; NONHUMAN; PRIORITY JOURNAL; PROTEIN LIPID INTERACTION; RAT; STRUCTURE ANALYSIS; THROMBOCYTE; THROMBOCYTE AGGREGATION INHIBITION;

EID: 0033304016     PISSN: 07673981     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1472-8206.1999.tb00327.x     Document Type: Article

References (14)

1. Protective antithrombotic action of the preparation from the leeches Hirudo medicinalis
2. Micellar enzymology: Its relation to membranology
3. Inhibition of thrombin
4. Inhibition of human blood plasma kallikrein by salivary gland secretion and extract of the medicinal leech
5. Destabilase, the novel ε-(γ-Glu)-Lys isopeptidase with thrombolytic activity
6. The reability of molecular weight determinations by dodecyl sulphate polyacrylamide gel electrophoresis
7. Aggregation of blood platelets
8. Protein measurement with the Folin phenol reagent
9. Synthetic chromogenic substrate for determination of trypsin
10. Spectrophotometrische Bestimmung des Kallikrein und Inhibotoren
11. Serum induced thrombosis studies of its induction and evolution under controlled conditions in vivo
12. Studies on antithrombotic effects of recombinant hirudin