Superantigens and their role in autoimmune disorders

Archivum Immunologiae et Therapiae Experimentalis

Volumn 47, Issue 1, 1999, Pages 17-24

  Schiffenbauer, Joel ^a  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

Autoimmune; Encephalomyelitis; Experimental allergic; Staphylococcal enterotoxin; Superantigen

Indexed keywords

LYMPHOCYTE ANTIGEN RECEPTOR; RECEPTORS, ANTIGEN, T CELL, ALPHA BETA; SUPERANTIGEN;

ANIMAL; AUTOIMMUNE DISEASE; GENETICS; HUMAN; IMMUNOLOGY; INSULIN DEPENDENT DIABETES MELLITUS; LYMPHOCYTE ACTIVATION; MUCOCUTANEOUS LYMPH NODE SYNDROME; PHYSIOLOGY; REVIEW; RHEUMATOID ARTHRITIS; T LYMPHOCYTE;

ANIMAL; ARTHRITIS, RHEUMATOID; AUTOIMMUNE DISEASES; DIABETES MELLITUS, INSULIN-DEPENDENT; HUMAN; LYMPHOCYTE ACTIVATION; MUCOCUTANEOUS LYMPH NODE SYNDROME; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; SUPERANTIGENS; T-LYMPHOCYTES;

EID: 0033302293     PISSN: 0004069X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (59)

1. ABE J., KOTZIN B. L., JUJO K., MELISH M. E., GLODE M. P., KOHSAKA T. and LEUNG D. Y. M. (1992): Selective expansion of T cells expressing T cell receptor variable region Vβ2 and Vβ8 in Kawasaki disease. Proc. Natl. Acad. Sci. USA, 89, 4066-4070.
2. ARNETT F. C. and SHULMAN L. E. (1976): Studies in familial systemic lupus erythematosus. Medicine, 55, 313-320.
3. BLOCK S. R., WINFIELD J. B., LOCKISHIN M. D., D'ANGELO W. A. and CHRISTIAN C. L. (1975): Studies of twins with systemic lupus erythematosus. Am. J. Med., 59, 533-551.
4. CACOUB P., FABIANI F. L., MUSSET L., PERRIN M., FRANGEUL L., LEGER J. M., HURAUX J. M., PIETTE, J. C. and GODEAU P. (1994): Mixed cryoglobulinemia and hepatitis C virus. Am. J. Med., 96, 124-131.
5. CHOI Y., LAFFERTY J. A., CLEMETS J. R., TODD J. K., GELFAND E. W., KAPPLER J., MARRACK P. and KOTZIN B. L. (1990): Selective expansion of T cells expressing Vβ2 in toxic shock syndrome. J. Exp. Med., 172, 981-984.
6. COLE B. C. and GRIFFITHS M. M. (1993): Triggering and exacerbation of autoimmune arthritis by the mycoplasma arthritidis superantigen MAM. Arthritis Rheum., 36, 994-1002.
7. CONRAD B., WELDMANN E., TRUCCO G., RUDERT W. A., BEHBOO R., RICORDI C., RODRIGUEZ-RILO H., FINEGOLD D. and TRUCCO M. (1994): Evidence for superantigen involvement in insulin-dependent diabetes mellitus aetiology. Nature, 371, 351-355.
8. CURTIS N., ZHENG R., LAMB J. R. and LEVIN M. (1995): Evidence for a superantigen medicated process Kawasaki disease. Arch. Dis. Child., 72, 308-311.
9. DAS M., COHEN A., ZAMVIL S. S., OFFNER H. and KUCHROO V. K. (1996): Prior exposure to superantigen can inhibit or exacerbate autoimmune encephalomyelitis: T cell repertoire engaged by the autoantigen determines clinical outcome. J. Neuroimmunol., 71, 3-10.
10. FRIEDMAN S. M., POSNETT D. N., TUMANG J. R., COLE B. C. and CROW M. K. (1991): A potential role for microbial superantigenis in pathogenesis of systemic autoimmune disease. Arthritis Rheum., 34, 468-480.
11. GOCKE D. J., MORGAN C., LOCKSHIN M., HSU K., BOMBARDIERI S. and CRISTIAN C. L. (1970): Association between polyarteritis and Australia antigen. Lancet, 5, 1149-1152.
12. GONZALO J., TARAZONA R., SCHUURMAN H., UYTDEHAAG F., WICK G., MARTINEZ C. and KROEMER G. (1994): A single injection of Staphylococcus aureus enterotoxin reduces autoimmunity in MRL/lpr mice. Clin. Immunol. Immunopathol., 71, 176-182.
13. HE X., GORONZY J. and WEYAND C. (1991): Selective induction of rheumatoid factors by superantigens and human helper T cells. J. Clin. Invest., 89, 673-680.
14. HENDERSON C. A. and HIGHET A. S. (1988): Acute psoriasis associated with Lancefield group C and group G cutaneous streptococcal infections. Br. J. Dermatol., 118, 559-562.
15. HOWELL M. D., DIVELEY J. P., LUNDEEN K. A., ESTY A., WINTERS S. T., CARLO D. J. and BROSTOFF S. W. (1991): Limited T-cell receptor β-chain heterogeneity among interleukin 2 receptor-positive synovial T cells suggests a role for superantigen in rheumatoid arthritis. Proc. Natl. Acad. Sci. USA, 88, 10921-10925.
16. KALMAN B., LUBLIN F. D., LATTIME E., JOSEPH J. and KNOBLER R. L. (1993): Effects of staphylococcal enterotoxin B on T cell receptor Vβ utilization and clinical manifestations of experimental allergic encephalomyelitis. J. Neuroimmunol., 45, 83-88.
17. + T cell in staphylococcal enterotoxin B-primed mice. J. Exp. Med., 2, 1065-1070.
18. + suppressor T cells in superantigen-treated non-obese diabetic mice J. Immunol., 151, 4362-4370.
19. KIM C., SIMINOVITCH K. A. and OCHI A. (1991): Reduction of lupus nephritis in MRL/lpr mice by a bacterial superantigen treatment. J. Exp. Med., 174, 1431-1437.
20. KINGSLEY G. and PANAYI G. S. (1997): Joint destruction in rheumatoid arthritis: biological bases. Clin. Exp. Rheumatol., 15 (suppl. 17), S3-14.
21. LEONARD J. P., WALDBURGER K. E., SCHAUB R. G., SMITH T., HEWSON A. K., CUZNER M. L. and GOLDMAN S. J. (1997): Regulation of the inflammatory response in animal models of multiple sclerosis in interleukin 12. Crit. Rev. Immunol., 17, 545-553.
22. LEUNG D. Y. M. (1990): Immunologic aspects of Kawasaki syndrome. J. Rheumatol., 24, 15-18.
23. LEUNG D. Y. M., BURNS J. C., NEWBURGER J. W. and GEHA R. S. (1987): Reversal of lymphocyte activation in vitro in the Kawasaki syndrome by intravenous gammaglobulin. J. Clin. Invest., 79, 468-472.
24. LEUNG D. Y. M., GIORNO R. C., KAZEMI L. V., FLYNN P. A. and BUSSE J. B. (1995): Evidence for superantigen involvement in cardiovascular injury due to Kawasaki syndrome. J. Immunol., 155, 5018-5021.
25. LEUNG D. Y. M., HARBECK R., BINA P., REISER R. F., YANG E., NORRIS D. A., HANIFIN J. M. and SAMPSON H. A. (1993): Presence of IgE antibodies of staphylococcal exotoxin on the skin of patients with atopic dermatitis. J. Clin. Invest., 92, 1374-1380.
26. LEUNG D. Y. M., HUBERT B. T. and SCHLIEVERT P. M. (1997): Historical perspective of superantigens and their biological activities. In: Superantigens. Marcel Dekker, New York, 1-13.
27. LEUNG D. Y. M., MEISSNER H. C., FULTON D. R., MURRAY D. L., KOTZIN B. L. and SCHLIEVERT P. M., (1993): Toxic shock syndrome toxin-secreting Staphylococcus aureus in Kawasaki syndrome. Lancet, 342, 1385-1388.
28. LEUNG D. Y. M., SIEGEL L., GRADY S., KRENSKY A., MEADE R., REINHERZ E. L. and GEHA R. S. (1982): Immunoregulatory abnormalities in mucocutaneous lymph node syndrome. Clin. Immunol. Immunopathol., 23, 100-112.
29. LEUNG D. Y. M., WALSH P., GIORNO R. and NORRIS D. A. (1993): A potential role for superantigens in the pathogenesis of psoriasis. J. Invest. Dermatol., 100, 225-228.
30. LEWIS H. M., BARKER B. S., BOKTH S., POWLES A. V., GARIOCH J. J., VALDIMARSSON H. and FRY L. (1993): Restricted T-cell receptor Vβ gene usage in the skin of patients with guttate and chronic plaque psoriasis. Br. J. Dermatol., 129, 514-520.
31. MARPLES R. R., HEATON C. L. and KLIGMAN A. M. (1973): Staphylococcus aureus in psoriasis. Arch. Dermatol., 107, 568-570.
32. MARRACK P. and KAPPLER J. (1990): The staphylococcal enterotoxins and their relatives. Science, 248, 705-711.
33. MEHINDATE K., AL-DACCAK R., SCHALL T. J. and MOURAD W. (1994): Induction of chemokine gene expression by major histocompatibility complex class II ligands in human fibroblast-like synoviocytes. J. Biol. Chem., 269, 32063-32069.
34. MOUNTZ J. D., ZHOU T., LONG R. E., BLUETHMANN H., KOOPMAN W. J. and EDWARDS C. K. (1994): T cell influence on superantigen-induced arthritis in MRL-lpr/lpr mice. Arthritis Rheum., 37, 113-124.
35. MOURAD W., MEHINDATE K., SCHALL T. J. and MC COLL S. R. (1992): Engagement of major histocompatibility complex class II molecules by superantigen induces inflammatory cytokine gene expression in human rheumatoid fibroblast-like synoviocytes. J. Exp. Med., 175, 613-616.
36. MOURAD W., SCHOLL P., DIAZ A., GEHA R. and CHATILA T. (1989): The staphylococcal toxic shock syndrome toxin 1 triggers B cell proliferation and differentiation via major histocompatibility complex-unrestricted cognate T/B cell interaction. J. Exp. Med., 170, 2011-2022.
37. ORIGUCHI T., EGUCHI K., KAWABE Y., MIZOKAMI A., IDA H. and NAGATAKI S. (1995): Synovial cells are potent antigen-presenting cells for superantigen, staphylococcal enterotoxin B (SEB). Clin. Exp. Immunol., 99, 345-351.
38. PALIARD X., WEST S. G., LAFFERTY J. A., CLEMENTS J. R., KAPPLER J. W., MARRACK P. and KOTZIN B. L. (1991): Evidence for the effect of a superantigen in rheumatoid arthritis. Science, 253, 325-328.
39. PIETRA B. A., INOCENCIO J. D., GIANNINI E. H. and HIRSCH R. (1994): TCR Vβ family repertoire and T cell activation markers in Kawasaki disease. J. Immunol., 153, 1881-1888.
40. ROSENBERG E. W. and NOAH P. W. (1988): The Koebner phenomenon and the microbial basis of psoriasis. J. Am. Acad. Dermatol., 18, 151-158.
41. ROSENBERG E. W., NOAH P. W., ZANOLLI M. D., SKINNER R. B., BOND M. J. and CRUTCHER N. (1986): Use of rifampin with penicillin and erythromycin in the treatment of psoriasis J. Am. Acad. Dermatol., 14, 761-764.
42. ROTT O., WEKERLE H. and FLEISCHER B. (1992): Protection form experimental allergic encephalomyelitis by application of a bacterial superantigen. Int. Immunol., 4, 347-353.
43. + T helper cells. Clin. Exp. Immunol., 99, 276-282.
44. SCHIEFFENBAUER J., JOHNSON H. M., BUTFILOSKI E. J., WEGRZYN L. and SOOS J. M. (1993): Staphylococcal enterotoxin can reactive experimental allergic encephalomyelitis. Proc. Natl. Acad. Sci. USA, 90, 8543-8546.
45. SCHWAB J. H., BROWN R. R., ANDERLE S. K. and SCHLIEVERT P. M. (1993): Superantigen can reactive bacterial cell wall-induced arthritis. J. Immunol., 150, 4151-4159.
46. SEGAL B. M., KLINMAN D. M. and SHEVACH E. M. (1997): Microbial products induce autoimmune disease by an IL-12-dependent pathway. J. Immunol., 158, 5087-5090.
47. SHINBORI T., MATSUKI M., SUGA M., KAKIMOTO K. and ANDO M. (1996): Pneumonia in autoimmune mice by intratracheal administration of superantigen staphylococcal enterotoxin B. Cell. Immmunol., 174, 129-137.
48. SKENN M. J., MILLER M. A., SHINNICK T. M. and ZIEGLER H. K. (1996): Regulation of murine macrophages IL-2 production. Activation of macrophages in vivo, restimulation in vitro, and modulation by other cytokines. J. Immunol., 156, 1196-1206.
49. SMITH T., HEWSON A. K., KINGSLEY C. I., LEONARD J. P. and CUZNER M. L. (1997): Interleukin 12 induces relaps experimental allergic encephalomyelitis in the Lewis rats. Am. J. Pathol., 150, 1909-1917.
50. SOOS J. M., HOBEIKA A. C., BUTFILOSKI E. J., SCHIFFENBAUER J. and JOHNSON H. M. (1995): Accelerated induction of experimental allergic encephalomyelitis in PL/J mice by a non-Vβ8-specific superantigen. Proc. Natl. Acad. Sci. USA, 92, 6082-6086.
51. SOOS J. M., SCHIFFENBAUER J. and JOHNSON H. M. (1993): Treatment of PL/J mice with the superantigen, staphylococcal enterotoxin B, prevents development of experimental allergic encephalomyelitis. J. Neuroimmunol., 43, 39-44.
52. STEGEMAN C. A., TERVAERT J. W., SLUITER W. J., MANSON W. L., DE JONG P. E. and KALLENBERG C. G. M. (1994): Association of chronic nasal carriage of Staphylococcus aureus and higher relapse rates in Wegener granulomatosis. Ann. Intern. Med., 120, 12-17.
53. TAKEI S., ARORA Y. and WALKER S. M. (1993): Intravenous immunoglobulin contains specific antibodies inhibitory to activation of T cells by staphylococcal toxin superantigen. J. Clin. Invest., 91, 602-607.
54. TREPO C. G., ZUCKERMAN A. J., BIRD R. C. and PRINCE A. M. (1974): The role of circulating hepatitis B antigen/antibody immune complexes in the pathogenesis of vascular and hepatic manifestations in polyarteritis nodosa. J. Clin. Pathol., 27, 863-868.
55. TUMANG J. R., POSNETT D. N., COLE B. C., CROW M. K. and FRIEDMAN S. M. (1990): Helper T cell-dependent human B cell differentiation mediated by a mycoplasmal superantigen bridge. J. Exp. Med., 171, 2153-2158.
56. WHYAND C. M. and GORONZY J. J. (1994): Functional domains on HLA-DR molecules: implication for the linkage of HLA-DR genes to different autoimmune disease. Clin. Immunol. Immunopathol., 70, 91-98.
57. WEYAND C. M., HICOK K. C., CONN D. L. and GORONZY J. J. (1992): The influence of HLA-DRB1 genes on disease severity in rheumatoid arthritis. Ann. Int. Med., 117, 801-806.
58. WHYTE H. J., BALGHMAN R. D. and HANOVER N. H. (1964): Acute guttate psoriasis and streptococcal infection. Arch. Dermatol., 89, 350-356.
59. WOOSLEY R. L., DRAYER D. E., REIDENBERG M. M., NIES A. S., CARR K. and OATES J. A. (1978): Effect of acetylator phenotype on the rate at which procainamide induces antinuclear antibodies and the lupus syndrome. N. Engl. J. Med., 298, 1157-1159.