Early changes in β-cell function nd insulin pulsatility as predictors for type 2 diabetes;Modifications precoces de la fonction des cellules beta-pancreatiques et de la pulsatilite de l'insuline comme predicteurs du diabete de type 2

Diabetes and Metabolism

Volumn 25, Issue SUPPL. 7, 1999, Pages 14-16

  Porksen N ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

CONFERENCE PAPER; HUMAN; HYPERGLYCEMIA; INSULIN DEPENDENT DIABETES MELLITUS; INSULIN RELEASE; INSULIN RESISTANCE; NON INSULIN DEPENDENT DIABETES MELLITUS; PANCREAS ISLET BETA CELL; ARTICLE; BLOOD; PANCREAS ISLET; PATHOPHYSIOLOGY; PREDICTION AND FORECASTING; SECRETION;

INSULIN;

DIABETES MELLITUS, TYPE 2; HUMANS; HYPERGLYCEMIA; INSULIN; INSULIN RESISTANCE; ISLETS OF LANGERHANS; PREDICTIVE VALUE OF TESTS;

EID: 0033289794     PISSN: 03381684     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (6)

1. Pørksen N., Nyholm B., Veldhuis J.-D., Butler P.-C., Schmitz O., In humans at least 75% of insulin secretion arises from punctuated insulin secretory bursts. American Journal of Physiology 1997 ; 273 (5 Pt 1) : E908.
2. Cunningham B.-A., Deeney J.-T., Bliss C.-R., Corkey B.-E., Tornheim K., Glucose-induced oscillatory insulin-secretion in perifused rat pancreatic-islets and clonal beta-cells (hit). American Journal of Physiology-Endocrinology and Metabolism 1996 ; 34 (4) : E702-E710.
3. Longo E.-A., Tornheim K., Deeney J.-T., Vamum B.-A., Tillotson D., Prentki M., Corkey B.-E., Oscillations in cytosolic free Ca2+, oxygen consumption, and insulin secretion in glucose-stimulated rat pancreatic islets. Journal of Biological Chemistry 1991 ; 266 (14) : 9314-9319.
4. Polonsky K.-S., Given B.-D., Hirsch L.-J., Tillil H., Shapiro E.-T., Beebe C., Frank B.-H., Galloway J.-A., Van Cauter E., Abnormal patterns of insulin secretion in non-insulin-dependent diabetes mellitus. New England Journal of Medicine 1988 ; 318 (19) : 1231-1239.
5. O'Rahilly S., Turner R.-C, Matthews D.-R., Impaired pulsatile secretion of insulin in relatives of patients with non-insulin-dependent diabetes. New England Journal of Medicine 1988 ; 318 (19) : 1225-1230.
6. Schmitz O., Pørksen N., Nyholm B., Skjaerbaek C., Butler P.-C., Veldhuis J.-D., Pincus S.M., Disorderly and nonstationary insulin secretion in relatives of patients with NIDDM. American Journal of Physiology 1997 ; 272 (2 Pt I) : E218.