Analysis of the amino acid indospicine in biological samples by high performance liquid chromatography

Natural Toxins

Volumn 7, Issue 6, 1999, Pages 233-240

  Pollitt, Sandra ^a   Hegarty, Mervyn P ^b   Pass, Michael A ^a,c  

^a UNIVERSITY OF QUEENSLAND   (Australia)

^b Plantchem Pty Ltd   (Australia)

^c UNIVERSITY OF THE SUNSHINE COAST   (Australia)

Author keywords

Horse serum; Horsemeat; HPLC; Indigofera spp; Indospicine; Phenylisothiocyanate

Indexed keywords

AMINO ACID; AMINOCAPROIC ACID DERIVATIVE; HYDROCHLORIC ACID; INDOSPICINE; PHENYL ISOTHIOCYANATE; UNCLASSIFIED DRUG; WATER;

AMINO ACID ANALYSIS; ANALYZER; ANIMAL FOOD; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALIBRATION; DERIVATIZATION; EXTRACTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HORSE; LEGUME; LIVER TOXICITY; NONHUMAN; RELIABILITY; SAMPLE; SERUM; TECHNIQUE; TIME; ULTRAFILTRATION; ULTRAVIOLET RADIATION;

ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HORSES; MEAT; NORLEUCINE; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY;

EQUIDAE; EQUUS CABALLUS; INDIGOFERA;

EID: 0033286132     PISSN: 10569014     EISSN: None     Source Type: Journal    
DOI: 10.1002/1522-7189(199911/12)7:6<233::AID-NT59>3.0.CO;2-3     Document Type: Article

References (19)

1. Effects on the liver in the rat of ingestion of Indigofera spicata, a legume containing an inhibitor of arginine metabolism
2. Effects of an arginine antagonist on stimulated human lymphocytes in culture
3. Acute biochemical changes in rat liver induced by the naturally occurring amino acid indospicine
4. The effects of indospicine on bone marrow cells in liquid culture
5. Indospicine, an hepatotoxic amino acid from Indigofera spicata
6. Hepatotoxicity to dogs of horsemeat contaminated with indospicine
7. Indospicine, a hepatotoxic amino acid from Indigofera spicata: Isolation structure, and biological studies
8. Amino acid analysis by reverse-phase high-performance liquid chromatography: Precolumn column derivatization with phenylisothiocyanate
9. Studies on the toxicity of Indigofera endecaphylla. I. Toxicity for rabbits
10. Studies on the toxicity of Indigofera endecaphylla. II. Toxicity for mice
11. The hepatotoxicity of indospicine in dogs
12. 14C into protein and transfer ribonucleic acid by cell-free systems from rat liver
13. Inhibition of rat liver homogenate arginase activity in vitro by the hepatotoxic amino acid indospicine
14. Effects of the naturally occurring arginine analogues indospicine and canavanine on nitric oxide mediated functions in aortic endothelium and peritoneal macrophages
15. Analytical methods validation: Bioavailability, bioequivalence, and pharmacokinetic studies
16. 14C] pimelic acid