Functional analyses of natural variation in Sp1 binding sites of a TATA-less promoter

Journal of Molecular Evolution

Volumn 49, Issue 6, 1999, Pages 736-749

  Segal, Jeff A ^a   Barnett, J Lynn ^b   Crawford, Douglas L ^b  

^a UNIVERSITY OF CHICAGO   (United States)

^b UNIVERSITY OF MISSOURI KANSAS CITY   (United States)

Author keywords

Binding affinities; Evolutionary adaptation; Phylogeny; Transcription

Indexed keywords

LACTATE DEHYDROGENASE; NUCLEAR PROTEIN; TRANSCRIPTION FACTOR SP1;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BINDING SITE; CELL NUCLEUS; CONTROLLED STUDY; DROSOPHILA; GEL MOBILITY SHIFT ASSAY; LIVER CELL; NONHUMAN; PHYLOGENY; PROMOTER REGION; PROTEIN EXPRESSION; TATA BOX; TELEOST; TRANSCRIPTION REGULATION;

ANIMALIA; FUNDULUS HETEROCLITUS; TELEOSTEI;

EID: 0033280322     PISSN: 00222844     EISSN: None     Source Type: Journal    
DOI: 10.1007/PL00006596     Document Type: Article

References (67)

1. Promoter elements in Drosophila melanogaster revealed by sequence analysis
2. Transcription from TATA-less promoters: Dihydrofolate reductase as a model
3. Phylogenetic relationships among nine species from the genus Fundulus (Cyprinodontiformes, Fundulidae) inferred from sequences of the cytochrome B
4. A TATA-less promoter containing binding sites for ubiquitous transcription factors mediates cell type-specific regulation of the gene for transcription enhancer factor-1 (TEF-1)
5. MAZ, a zinc finger protein, binds to c-MYC and C2 gene sequences regulating transcriptional initiation and termination
6. Phylogenetic studies of the genus Fundulus
7. In vivo role of the Sp1 site neighboring sterol-responsive element-l in controlling low-density lipoprotein receptor gene expression
8. The binding of transcription factor Sp1 to multiple sites is required for maximal expression from the rat transforming growth factor alpha promoter
9. Identification of a silencer module which selectively represses cyclic AMP-responsive element-dependent gene expression
10. Cooperation between core promoter elements influences transcriptional activity in vivo
11. Analysis of Sp1 in vivo reveals multiple transcriptional domains, including a novel glutamine-rich activation motif
12. Molecular basis of evolutionary adaptation at the lactate dehydrogenase-B locus in the fish Fundulus heteroclitus
13. Evolutionary adaptation to different thermal environments via transcriptional regulation
14. Evolutionary physiology of closely related taxa: Analyses of enzyme expression
15. Evolutionary analysis of TATA-less proximal promoter function
16. Dephosphorylation of Sp1 by protein phosphatase 1 is involved in the glucose-mediated activation of the acetyl-coa carboxylase gene
17. Repeated CT elements bound by zinc finger proteins control the absolute and relative activities of the two principal human c-myc promoters
18. The promoter-specific transcription factor Sp1 binds to upstream sequences in the SV40 early promoter
19. Combinatorial regulation of transcription II: The immunoglobulin mu heavy chain gene
20. A promoter of the rat insulin-like growth factor II gene consists of minimal control elements
21. Compilation of vertebrate-encoded transcription factors
22. Contacts in context: Promoter specificity and macromolecular interactions in transcription
23. Tissue-specific in vitro transcription from the mouse albumin promoter
24. Phylogenetic footprinting reveals unexpected complexity in trans factor binding upstream from the epsilon-globin gene
25. Differential phylogenetic footprinting as a means to identify base changes responsible for recruitment of the anthropoid gamma gene to a fetal expression pattern
26. Evolutionary strategies for the elucidation of cis and trans factors that regulate the developmental switching programs of the beta-like globin genes
27. Sp1-mediated transcriptional activation is repressed by Sp3
28. Inhibition of colony-stimulating factor-1 promoter activity by the product of the Wilms' tumor locus
29. A transcriptional role for conserved footprinting sequences within the larval promoter of a Drosophila alcohol dehydrogenase gene
30. Signal, noise, reliability in molecular phylogenetic analyses
31. Two regulatory proteins that bind to the basic transcription element (BTE), a GC box sequence in the promoter region of the rat P-4501A1 gene
32. O-glycosylation of eukaryotic transcription factors: Implications for mechanisms of transcriptional regulation
33. Phosphorylation of transcription factor Sp1 by the DNA-dependent protein kinase
34. Multiple protein-DNA interactions in the TATAA-less mouse thymidylate synthase promoter
35. Activation of the AIDS retrovirus promoter by the cellular transcription factor
36. Isolation of cDNA encoding transcription factor Sp1 and functional analysis of the DNA binding domain
37. Distinct regions of Sp1 modulate DNA binding and transcriptional activation
38. Nuclear factor ETF specifically stimulates transcription from promoters without a TATA box
39. Egr-1-induced endothelial gene expression: A common theme in vascular injury
40. A single-base substitution in the proximal Sp1 site of the human low density lipoprotein receptor promoter as a cause of heterozygous familial hypercholesterolemia
41. Start site selection at the TATA-less carbamoyl-phosphate synthase (glutamine-hydrolyzing)/aspartate carbamoyltransferase/dihydroorotase promoter
42. Sequence-specific recognition of DNA by zinc-finger peptides derived from the transcription factor Sp1
43. Genomic structure and regulation of the promoter of the rat insulin-like growth factor binding protein-2 gene
44. Sp1 is phosphorylated and its DNA binding activity down-regulated upon terminal differentiation of the liver
45. Measurement of the binding of transcription factor Sp1 to a single GC box recognition sequence
46. Start site selection by Sp1 in the TATA-less human Ha-ras promoter
47. Roles of TATA and initiator elements in determining the start site location and direction of RNA polymerase II transcription
48. Different activation domains of Sp1 govern formation of multimers and mediate transcriptional synergism
49. Phylogenetic analysis of glycolytic enzyme expression
50. Phylogenetic analysis of thermal acclimation of the glycolytic enzymes in the genus Fundulus
51. Derivatives of Moloney murine sarcoma virus capable of being transcribed in embryonal carcinoma stem cells have gained a functional Sp1 binding site
52. Transcription from a TATA-less promoter requires a multisubunit TFIID complex
53. The complexities of eukaryotic transcription initiation: Regulation of preinitiation complex assembly
54. Overlapping Pit-1 and Sp1 binding sites are both essential to full rat growth hormone gene promoter activity despite mutually exclusive Pit-1 and Sp1 binding
55. LDH-B enzyme expression: The mechanisms of altered gene expression in acclimation and evolutionary adaptation
56. Descriptive and functional characterization of variation in the Fundulus heteroclitus Ldh-B proximal promoter
57. Core promoter architecture for eukaryotic protein-coding genes
58. Comparison of DNA-binding properties between BTEB and Sp1
59. Wnt-1-inducing factor-1: A novel G/C box-binding transcription factor regulating the expression of Wnt-1 during neuroectodermal differentiation
60. Binding of TAFs to core elements directs promoter selectivity by RNA polymerase II
61. A study of the evolutionary relationships of Fundulus topminnows (Teleostei: Fundulidae)
62. Functional binding of the "TATA" box binding component of transcription factor TFIID to the -30 region of TATA-less promoters
63. Mechanism of initiator-mediated transcription: Evidence for a functional interaction between the TATA-binding protein and DNA in the absence of a specific recognition sequence
64. HIV-1 core promoter lacks a simple initiator element but contains a bipartite activator at the transcription start site