Synthesis of methylglyoxal thiosemicarbazone and its copper-containing complex possessing DNA-inhibiting and antitumor activity

Pharmaceutical Chemistry Journal

Volumn 33, Issue 11, 1999, Pages 579-581

  Mamashvili, T N ^a   Keiko, N A ^a   Chipanina, N N ^a   Voronkov, M G ^a   Potapova, G I ^b   Gudratov, N O ^b   Treshchalina, E M ^b  

^a A E FAVORSKY IRKUTSK INSTITUTE OF CHEMISTRY   (Russian Federation)

^b N N BLOKHIN RUSSIAN CANCER RESEARCH CENTER   (Russian Federation)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; COPPER COMPLEX; DNA; METHYLGLYOXAL; THIOSEMICARBAZONE DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL CULTURE; CONTROLLED STUDY; DNA SYNTHESIS INHIBITION; DOSE RESPONSE; DRUG HYDROLYSIS; DRUG MECHANISM; DRUG SCREENING; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; FEMALE; INTESTINE CELL; KIDNEY CELL CULTURE; LD 50; MALE; MOUSE; NONHUMAN; PROTEIN DNA INTERACTION; SPLEEN CELL; TUMOR;

EID: 0033270846     PISSN: 0091150X     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02508278     Document Type: Article

References (7)