The use of [9,10-3H]myristate, [9,10-3H]palmitate and [9,10-3H]oleate for the detection and diagnosis of medium and long-chain fatty acid oxidation disorders in intact cultured fibroblasts

Advances in Experimental Medicine and Biology

Volumn 466, Issue , 2000, Pages 321-325

  Olpin, S E ^a   Manning, N J ^a   Pollitt, R J ^a   Bonham, J R ^a   Downing, M ^a   Clark, S ^a  

^a SHEFFIELD CHILDREN S HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACYL COENZYME A DEHYDROGENASE; CARNITINE PALMITOYLTRANSFERASE; LONG CHAIN FATTY ACID; MEDIUM CHAIN FATTY ACID; MYRISTIC ACID; OLEIC ACID; PALMITIC ACID; TRITIUM; ACYL COENZYME A DESATURASE; LONG CHAIN ACYL COENZYME A DEHYDROGENASE;

ACYL COENZYME A DEHYDROGENASE DEFICIENCY; CARNITINE DEFICIENCY; CELL CULTURE; CONFERENCE PAPER; CONTROLLED STUDY; ENZYME DEFICIENCY; FATTY ACID OXIDATION; FIBROBLAST; HUMAN; HUMAN CELL; ISOTOPE LABELING; PRIORITY JOURNAL; RESPIRATORY CHAIN; ARTICLE; DISORDERS OF LIPID AND LIPOPROTEIN METABOLISM; METABOLISM;

TRITIUM;

ACYL-COA DEHYDROGENASE, LONG-CHAIN; CELLS, CULTURED; FATTY ACID DESATURASES; FIBROBLASTS; HUMANS; LIPID METABOLISM, INBORN ERRORS; MYRISTIC ACID; OLEIC ACID; PALMITIC ACID; TRITIUM;

EID: 0033256143     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: None     Document Type: Conference Paper

References (5)

1. 3H]myristic acids for the detection of fatty acid oxidation defects in intact cultured fibroblasts
2. 3H]palmitic acids by intact cultured fibroblasts
3. Rapid diagnosis of long and medium chain fatty acid oxidation disorders using lymphocytes
4. 3H]oleate
5. Mitochondrial very-long-chain acyl-coenzyme A dehydrogenase deficiency: Clinical characteristics and diagnostic considerations in 30 patients