Isolation and characterization of the eighth component of the bovine complement system

American Journal of Veterinary Research

Volumn 60, Issue 12, 1999, Pages 1474-1477

  Menger, Marilyn ^a,b   Sowery, Richard D ^a   Aston, W Peter ^a  

^a QUEEN S UNIVERSITY   (Canada)

^b GENVEC INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENT COMPONENT C8;

ANIMAL; ANIMAL DISEASE; ARTICLE; CATTLE; HUMAN; IMMUNOLOGY; ISOLATION AND PURIFICATION; MOLECULAR WEIGHT; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN CONFORMATION;

ANIMALS; CATTLE; COMPLEMENT C8; ELECTROPHORESIS, POLYACRYLAMIDE GEL; HUMANS; MOLECULAR WEIGHT; PROTEIN CONFORMATION;

EID: 0033253995     PISSN: 00029645     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (19)

1. Esser AF. The membrane attack complex of complement assembly, structure and cytotoxic activity. Toxicology 1994;87:229-247.
2. Lachmann PJ. The control of homologous lysis. Immunol Today 1991;12:312-315.
3. Aston WP, Mhatre A, Macrae J. Isolation of the fifth component of the bovine complement system. Vet Immunol Immunopathol 1990;24:301-312.
4. Eisenschenk FC, Houle JJ, Hoffmann EM. Purification of the ninth component of the bovine complement cascade. Am J Vet Res 1992;53:435-439.
5. Shin ML, Carney DF. Cytotoxic action and other metabolic consequences of terminal complement proteins. Prog Allergy 1988;40: 44-81.
6. Ng SC, Sodetz JM. Biosynthesis of C8 by hepatocytes. Differential expression and intracellular association of the α-γ and β-subunits. J Immunol 1987;139:3021-3027.
7. Esser AF, Sodetz JM. Membrane attack complex proteins. C5b-6, C7, C8 and C9 of human complement. Methods Enzymol 1998;162:551-578.
8. Biesecker G, Muller-Eberhard HJ. The ninth component of complement: purification and physicochemical characterization. J Immunol 1980;124:1291-1296.
9. Laemmli UK. Cleavage of structural proteins during assembly of the head of bacteriophage T4. Nature 1970;227:680-685.
10. Steckel EW, York RG, Monahan JB, et al. The eighth component of human complement. Purification and physicochemical characterization of its unusual subunit structure. J Biol Chem 1980;255:11997-12005.
11. Kinoshita T, Hong K, Kondo K. et al. Eighth component of guinea-pig complement. Purification and characterization. Mol Immunol 1982;19:589-597.
12. Jones J, Laffafian I, Morgan BP. Purification of C8 and C9 from rat serum. Complement Inflamm 1990;7:42-51.
13. TschoppJ, Jongeneel CV. Cytotoxic T lymphocyte mediated cytolysis. Biochemistry 1988;27:2641-2646.
14. Haefliger J A, Peitsch MC, Jenne DE, et al. Structural and functional characterization of complement C8γ, a member of the lipocalin protein family. Mol Immunol 1991;28:123-131.
15. Hänsch GM, Rummel G, Gänzler F. Purification and characterization of the ninth component of rabbit complement. Complement 1984;1:116-122.
16. Young JD-E, Cohn ZA, Podack ER. The ninth component of complement and the pore-forming protein (Perforin 1) from cytotoxic T cells: structural, immunological and functional similarities. Science 1986;233:184-190.
17. Taylor KM, Morgan BP, Campbell AK. Altered glycosylation and selected mutation in recombinant human complement component C9: effects on haemolytic activity. Immunology 1994;83: 501-506.
18. Houle JJ, Hoffmann EM, Esser AF. Restriction of cell lysis by homologous complement. II. Protection of erythrocytes against lysis by newly activated complement. Blood 1988;71:287-292.
19. Yarnall DP, Boyle MDP. Restriction in the lytic efficiency of complement on different erythrocyte targets: a re-examination of the activities of horse C8 and C9. Mol Immunol 1986;23:823-829.