Ocular pulse amplitude, intraocular pressure and β-blocker/carbonic anhydrase combination therapy;Okulare pulsamplitude, intraokularer druck und betablocker/karboanhydrasehemmung in der kombinationstherapie beim primaren offenwinkelglaukom

Klinische Monatsblatter fur Augenheilkunde

Volumn 215, Issue 6, 1999, Pages 361-366

  Schmidt, Karl Georg ^a   Rückmann, Andrea V ^a   Becker, Ralph ^a   Pillunat, Lutz E ^b  

^a UNIVERSITY HOSPITAL GIESSEN   (Germany)

^b UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

Author keywords

Choroid; Choroidal perfusion; Intraocular pressure; Ocular pulse amplitude; Primary open angle glaucomas

Indexed keywords

BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CARBONATE DEHYDRATASE INHIBITOR; DORZOLAMIDE; TIMOLOL; EYE DROPS; SULFONAMIDE; THIOPHENE DERIVATIVE;

ADULT; AGED; ARTICLE; CHOROID; CLINICAL ARTICLE; EYE BLOOD FLOW; FEMALE; GLAUCOMA; HUMAN; INTRAOCULAR PRESSURE; MALE; OPEN ANGLE GLAUCOMA; TREATMENT OUTCOME; BLOOD PRESSURE; CLINICAL TRIAL; COMPARATIVE STUDY; DRUG COMBINATION; DRUG EFFECT; EYE; MIDDLE AGED; PATHOPHYSIOLOGY; PHYSIOLOGY; PULSATILE FLOW; VASCULARIZATION;

ADRENERGIC BETA-ANTAGONISTS; AGED; BLOOD PRESSURE; CARBONIC ANHYDRASE INHIBITORS; DRUG THERAPY, COMBINATION; EYE; FEMALE; GLAUCOMA, OPEN-ANGLE; HUMANS; INTRAOCULAR PRESSURE; MALE; MIDDLE AGED; OPHTHALMIC SOLUTIONS; PULSATILE FLOW; SULFONAMIDES; THIOPHENES; TIMOLOL;

EID: 0033253217     PISSN: 00232165     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2008-1034733     Document Type: Article

References (61)

1. Alm A. Physiologie der okulären Durchblutung. In: Stodtmeister R, Christ Th, Pillunat LE, Ulrich WD, (Hrsg) Okuläre Durchblutungsstörungen, 1. Aufl., Stuttgart: Enke 1987:9-17
2. Alm A. Ocular circulation. In: Hart WM, (Hrsg) Adler's physiology of the eye, 9. Aufl., St. LouisCV: Mosby 1992:198-227
3. Alm A, Bill A. The oxygen supply to the retina. II. Effects of high intraocular pressure and increased arterial carbon dioxide tension on uveal and retinal blood flow in cats. Acta Physiol Scand 1972; 84:306-319
4. Alm A, Bill A. Ocular and optic nerve blood flow at normal and increased intraocular pressures in monkeys (Macaca irus): A study with radioactively labelled microspheres including flow determinations in brain and some other tissues. Exp Eye Res 1973; 15:15-29
5. Alm A, Bill A, Young FA. The effects of pilocarpine and neostigmine on the ocular blood flow through the anterior uvea in monkeys. A study with radioactively labelled microspheres. Exp Eye Res 1973; 15:31-36
6. Harris A, Arend O, Arend S, Martin B. Effects of topical dorzolamide on retinal and retrobulbar hemodynamics. Acta Ophthalmol Scand 1996; 74:569-572
7. Baldwin J, Ponticello G, Anderson P, et al. Thienothiopyran-2-sulfonamides: novel topically active carbonic anhydrase inhibitors for treatment of glaucoma. J Med Chem 1989; 32:2510-2513
8. Bartels SP. Aqueous humor flow measured with fluorophotometry in timolol-treated primates. Invest Ophthalmol Vis Sci 1988; 29:1489-1504
9. Bartels SP, Roth O, Jumblatt MM, Neufeld AH. Pharmacological effects of topical timolol in rabbit eyes. Invest Ophthalmol Vis Sci 1980; 19:1189-1197
10. Bill A. Blood circulation and fluid dynamics in the eye. Physiol Rev 1975; 55:383
11. Boles Carenini A, Sibour G, Boles-Carenini B. Differences in the long-term effect of timolol and betaxolol on the pulsatile ocular blood flow. Surv Ophthalmol 1994; 8 [Suppl]:118-124
12. Brechue WF, Maren TH. A comparison between the effect of topical and systemic carbonic anhydrase inhibitors on aqueous humor secretion. Exp Eye Res 1993; 57:67-78
13. Coakes RL, Brubaker RF. The mechanism of timolol in lowering intraocular pressure. Arch Ophthalmol 1978; 96:2045-2048
14. Drance SM, Douglas GR, Wijsman K, Schulzer M, Britton RJ. Response of blood flow to warm and cold in normal and low tension glaucoma. Graefes Arch Clin Exp Ophthalmol 1989; 227:408-412
15. Flammer J. Psychophysical mechanisms and treatment of vasospastic disorders in normal-tension glaucoma. Bull Soc Belge Ophthalmol 1992; 244:129-134
16. Flammer J, Gasser P, Prünte Ch, Yao K. The probable involvement of factors other than intraocular pressure in the pathogenesis of glaucoma. In: Drance SM, Buskirk EM van, Neufeld AH, (Hrsg) Pharmacology of Glaucoma, 1. Aufl., Baltimore: Williams and Wilkins 1992:273-283
17. Flammer J, Guthauser U. Behandlung chorioidaler Vasospasmen mit Kalziumantagonisten. Klin Monatsbl Augenheilkd 1987; 190:299-300
18. Friedmann E, Kopald H, Smith T. Retinal and choroidal blood flow determined with krypton-85 in anesthesized animals. Invest Ophthalmol Vis Sci 1964; 3:539-547
19. Galin MA, Best M. Studies in intraocular vascular dynamics. Trans Ophthalmol Soc UK 1971; 91:279-290
20. Gaspar AZ, Flammer J, Hendrickson P. Influence of nifedipine on the visual fields of patients with optic nerve head diseases. Eur J Ophthalmol 1994; 4:24-28
21. Gasser P, Flammer J. Influence of vasospasm on visual function. Doc Ophthalmol 1987; 66:3-18
22. Gasser P, Flammer J. Short- and long-term effect of nifedipine on the visual field in patients with presumed vasospasm. J Int Med Res 1990; 18:334-339
23. Gasser P, Flammer J, Guthauser U, Mahler F. Do vasospasms provoke ocular diseases? Angiology 1990; 41:213-220
24. Harris A, Sergott, RC, Spaeth GL, et al. Color doppler analysis of ocular vessel blood velocity in normal-tension glaucoma. Am J Ophthalmol 1994; 118:642-649
25. Kitazawa Y, Shirai H, Go FJ. The effect of a Ca++antagonist on visual field in low tension glaucoma. Graefes Arch Clin Exp Ophthalmol 1989; 227:408-112
26. Langham ME. Ocular blood flow and glaucomatous eyes. In: Krieglstein GK, (Hrsg) Glaucoma Update III, 1. Aufl. Berlin. Heidelberg, New York: Springer 1987:58-66
27. Langham ME. The influence of timolol, clonidine and aminoclonidine on pulsatile blood flow in the rabbit and human subjects. Invest Ophthalmol Vis Sci (1990) 31[Suppl]:242
28. Lawrence C, Schlegel WA. Ophthalmic pulse studies. I. Influence of intraocular pressure. Invest Ophthalmol Vis Sci 1966; 5:515-525
29. Lippa EA, Carlson LE, Ehinger B, et al. Dose response and duration of action of dorzolamide, a topical carbonic anhydrase inhibitor. Arch Ophthalmol 1992; 110:495-499
30. Liu HK, Chiou GC, Garg LC. Ocular hypotensive effect of timolol in cat eyes. Arch Ophthalmol 1980; 98:1467-1469
31. Eichhorn M, Schreckenberger M, Tamm ER, Lütjen-Drecoll E. Carbonic anhydrase activity is increased in retinal pigment epithelium and choriocapillaris of RCS rats. Graefes Arch Clin Exp Ophthalmol 1996; 234:258-263
32. Maren TH. Carbonic anhydrase: general perspectives and advances in glaucoma research. Drug Dev Res 1987; 10:255-276
33. Maren TH, Conroy CW. A new class of carbonic anhydrase inhibitor. J Biol Chem 1993; 268:26233-26239
34. Müchi H, Nagataki S. Effects of pilocarpine, salbutamol, and timolol on aqueous humor formation in cynomolgus monkeys. Invest Ophthalmol Vis Sci 1983; 24:1269-1271
35. Mittag TW, Serle J, Schumer R, et al. Studies of the ocular pulse in primates. Surv Ophthalmol 1994; 38 [Suppl]:183-190
36. Morsman CD, Bosem ME, Lusky M, Weinreb RN. The effect of topical beta-adrenoceptor blocking agents on pulsatile ocular blood flow. Eye 1995; 9:344-347
37. Netland PA, Chaturvedi N, Dreyer EB. Calcium channel blockers in the management of low tension and open-angle glaucoma. Am J Ophthalmol 1993; 115:608-613
38. Pfeiffer N. The potential for topical carbonic anhydrase inhibitors in glaucoma therapy. Current Opinion in Ophthalmology 1994; 5:20-25
39. Phelps CD, Corbett JJ. Migraine and low tension glaucoma. A case control study. Invest Ophthalmol Vis Sci 1985 26:1105-1108
40. Pillunat LE, Stodtmeister R, Marquardt R, Mattern A. Ocular perfusion pressures in different types of glaucoma. Im Ophthalmol 1989; 13:37-42
41. Postiglione A, Bobkiewicz T, Vinholdt-Pedersen E, et al. Cerebrovascular effects of angiotensin converting enzyme inhibition involve large artery dilation in rats. Stroke 1991; 22:1363-1368
42. Prünte Ch, Flammer J. Choroidal angiographic findings in patients with glaucoma-like visual field defects. In: Heijl A, (Hrsg) Perimetry Update 1988/89, 1. Aufl. Amsterdam: Kugler & Ghedini 1989:325-327
43. Quigley HA, Hohmann RM, Addicks EM, Green WR. Blood vessels of the glaucomatous optic disc in experimental primate and human eyes. Invest Ophthalmol Vis Sci 1984; 25:918-931
44. Ridderstrale Y, Wistrand PJ, Brechue WF. Membrane-associated CA activity in the eye of the CA II-deficient mouse. Invest Ophthalmol Vis Sci 1994; 35:2577-2584
45. Riva CE, Grunwald JE, Sinclair SE, Petrig BL. Blood viscosity and volumetric flow rate in human retinal vessels. Invest Ophthalmol Vis Sci 1985; 26:1124-1132
46. Rojanapongpun P, Drance SM, Morrison BJ. Ophthalmic artery flow velocity in glaucomatous and normal subjects. Br J Ophthalmol 1993; 77:25-29
47. Schmidt KG, Mittag TW, Pavlovic S, Hessemer V. Influence of physical exercise and nifedipine on ocular pulse amplitude. Graefes Arch Clin Exp Ophthalmol 1996; 234:527-532
48. Schmidt KG, v. Rückmann A, Mittag TW, Hessemer V, Pillunat LE. Reduced ocular pulse amplitude in low tension glaucoma is independent of vasospasm. EYE 1997; 11:485-488
49. Schmidt KG, v. Rückmann A, Mittag TW. Okuläre Pulsamplitude bei okulärer Hypertension und verschiedenen Glaukomformen. Ophthalmologica 1998; 212:5-10
50. Schmidt KG, Mittag TW. In: Schmidt KG. (Hrsg) Ein vasodilatativer Therapieansatz bei Normaldruckglaukom. In: Glaukom - Aktuelle Diagnostik und Therapie. München: Ad manum medici 1998:47-56
51. Schmidt KG, v. Rückmann A, Pillunat LE. Dorzolamide increases ocular pulse amplitude in high tension primary open angle glaucoma Br J Ophthalmol 1998; 82:758-762
52. Sonntag JR, Brindley GO, Shields MB. Effect of timolol therapy on outflow facility. Invest Ophthalmol Vis Sci 1978; 17:293-296
53. Schwartz B. Changes in optic disk in ocular hypertension and glaucoma. Jpn J Ophthalmol 1986; 30:143-153
54. Topper JE, Brubaker RF. Effects of timolol, epinephrine, and azetazolamide on aqueous humor flow during sleep. Invest Ophthalmol Vis Sci 1985; 26:1315-1319
55. Törnquist P, Alm A. Retinal and choroidal contribution to retinal metabolism in vivo. A study in pigs. Acta Physiol Scand 1979; 106:351-357
56. Trew DR, Smith SE. Postural studies in pulsatile ocular blood flow: II. Chronic open angle glaucoma. Br J Ophthalmol 1991; 75:71-75
57. Wilkerson M, Cyrlin M, Lippa EA, et al. Four-week safety and efficacy study of dorzolamide, a novel, active topical carbonic anhydrase inhibitor. Arch Ophthalmol 1993; 111:1343-1350
58. Yablonski ME, Zimmerman TJ, Waltman SR, Becker B. A fluorometric study of the effect of topical timolol on aqueous humor dynamics. Exp Eye Res 1978; 27:135-142
59. Zimmerman TJ, Kaufman HE. Timolol. A beta-adrenergic blocking agent for the treatment of glaucoma. Arch Ophthalmol 1977; 95:601-604
60. Zimmerman TJ, Kaufman HE. Timolol: dose response and duration of action. Arch Ophthalmol 1977; 95:605-607
61. Zimmerman TJ, Harbin R, Pett M, Kaufman HE. Timolol and facility of outflow. Invest Ophthalmol Vis Sci 1977; 16:623-624