A single amino—acid substitution in the yeast mevalonate diphosphate decarboxylase leads to a defect in the homodimerization of the protein

Acta Botanica Gallica

Volumn 146, Issue 1, 1999, Pages 117-120

  Cordier, Hélène ^a   Karst, Francis ^a   Bergès, Thierry ^a  

^a UNIVERSITÉ DE POITIERS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0033239309     PISSN: 12538078     EISSN: None     Source Type: Journal    
DOI: 10.1080/12538078.1999.10515808     Document Type: Article

References (6)

1. Bergès, T., Guyonnet, D., and Karst, F., 1997. The Saccharomyces cerevisiae mevalonate diphosphate decarboxylase is essential for viability, and a single Leu-to-Pro mutation in a conserved sequence leads to thermosensitivity. J Bacteriol., 179 (15):4664–4670.
2. Cardemil, E., and Jabalquinto, A. M., 1985. Mevalonate 5- pyrophosphate decarboxylase from chicken liver. Methods Enzymol., 110:86–92.
3. Chambón, C., Ladeveze, V., Servouse, M., Blanchard, L., Javelot, C., Vladescu, B., and Karst, F., 1991. Sterol pathway in yeast. Identification and properties of mutant strains defective in mevalonate diphosphate decarboxylase and farnesyl diphosphate synthetase.”. Lipids, 26 (8):633–636.
4. Fields, S., and Song, O., 1989. A novel genetic system to detect protein-protein interactions. Nature, 340 (6230):245–246.
5. Toth, M. J., and Huwyler, L., 1996. Molecular cloning and expression of the cDNAs encoding human and yeast mevalonate pyrophosphate decarboxylase. J Biol. Chem., 271 (14):7895–7898.
6. Toth, M. J., Huwyler, L., and Park, J., 1996. Purification of rat liver mevalonate pyrophosphate decarboxylase. Prep. Biochem. Biotechnol., 26 (1):47–51.