α1-Antitrypsin deficiency with fatal intracranial hemorrhage in a newborn

Journal of Pediatric Hematology/Oncology

Volumn 21, Issue 5, 1999, Pages 447-450

  Israels, Sara J ^a,c   Gilfix, Brian M ^b  

^a UNIVERSITY OF MANITOBA   (Canada)

^b MCGILL UNIVERSITY   (Canada)

^c UNIVERSITY OF MANITOBA   (Canada)

Author keywords

Cholestasis; Hemorrhagic disease of the newborn; Vitamin K deficiency; Vitamin K prophylaxis

Indexed keywords

DNA; OROSOMUCOID;

ALPHA 1 ANTITRYPSIN DEFICIENCY; ARTICLE; BRAIN HEMORRHAGE; BREAST FEEDING; CASE REPORT; CHOLESTASIS; COMPUTER ASSISTED TOMOGRAPHY; GENOTYPE; HUMAN; HUMAN TISSUE; MALE; NEWBORN; NEWBORN HEMORRHAGIC DISEASE; POINT MUTATION; PRIORITY JOURNAL; PROPHYLAXIS; SCREENING; VITAMIN K DEFICIENCY; BRAIN; FATALITY; GENETICS; HOMOZYGOTE; LIVER; PATHOLOGY; PHENOTYPE; RADIOGRAPHY;

ALPHA 1-ANTITRYPSIN DEFICIENCY; BRAIN; FATAL OUTCOME; GENOTYPE; HOMOZYGOTE; HUMANS; INFANT, NEWBORN; INTRACRANIAL HEMORRHAGES; LIVER; MALE; OROSOMUCOID; PHENOTYPE; POINT MUTATION; TOMOGRAPHY, X-RAY COMPUTED; VITAMIN K DEFICIENCY;

EID: 0033238240     PISSN: 10774114     EISSN: None     Source Type: Journal    
DOI: 10.1097/00043426-199909000-00022     Document Type: Article

References (22)

1. Golding J, Paterson M, Kinlen LJ. Factors associated with childhood cancer in a national cohort study. Br J Cancer 1990;62: 304-8.
2. Golding J, Greenwood R, Birmingham K, et al. Childhood cancer, intramuscular vitamin K, and pethidine given during labour. Br Med J 1992;305:341-6.
3. Klebanoff MA, Read JS, Mills JL, et al. The risk of childhood cancer after neonatal exposure to vitamin K. N Engl J Med 1993; 329:905-8.
4. Ekelund H, Finnstrom O, Gunnarskog J, et al. Administration of vitamin K to newborn infants and childhood cancer. Br Med J 1993;301:89-91.
5. Olsen JH, Hertz H, Blinkengerg K, et al. Vitamin K regimens and the incidence of childhood cancer in Denmark. Br Med J 1994; 308:895-6.
6. von Kries R, Gobel U, Hachmeister A, et al. Vitamin K and childhood cancer: A population-based case-control study in Lower Saxony, Germany. Br Med J 1996;313:199-203.
7. Zipursky A. Vitamin K at birth. Br Med J 1996;313:179-80.
8. von Kries R, Gobel U. Oral vitamin K prophylaxis and late haemorrhagic disease of the newborn. Lancet 1994;343:352.
9. Tazelaar JP, Friedman KJ, Kline RS, et al. Detection of alantitrypsin Z and S mutations by polymerase chain reaction-mediated site-directed mutagenesis. Clin Chem 1992;38:1486-8.
10. Hutchinson DCS. Natural history of alpha-1-protease inhibitor deficiency. Am J Med 1988;84(Suppl. 6A):3-12.
11. Brantley M, Nukiwa T, Crystal RC. Molecular basis of alpha-1-antitrypsin deficiency. Am J Med 1988;84(Suppl. 6A):13-31.
12. Fidalgo J, Vasquez C, Rodriguez-Soriano J. Intracranial hemorrhage due to vitamin K deficiency associated with alpha-1-antitrypsin deficiency type PiZ. Arch Dis Child 1982;57:722.
13. Hope PL, Hall MA, Millward-Sadler, et al. Alpha-1-antitrypsin deficiency presenting as a bleeding diathesis in the newborn. Arch Dis Child 1982;57:68-70.
14. Jenkins HR, Leonard JV, Kay JDS, et al. Alpha-1-antitrypsin deficiency, bleeding diathesis and intracranial haemorrhage. Arch Dis Child 1982;57:722-3.
15. Payne HR, Hasegawa DK. Vitamin K deficiency in newborns: A case report in alpha-1-antitrypsin deficiency and a review of factors predisposing to haemorrhage. Pediatrics 1984;73:712-6.
16. van den Aker JN, Sinaasappel M. Bleeding as presenting symptom of cholestasis. J Perinatol 1993;13:322-4.
17. Auerswald G, Sutor AH. Thirteen cases of α1-antitrypsin deficiency presenting as a bleeding diathesis with intracranial hemorrhage in the newborn. In: Sutor AH, Hathaway WE, eds. Vitamin K in infancy. Stuttgart: Schattauer, 1995:217-22.
18. von Kries R, Hanawa Y. Neonatal vitamin K prophylaxis. Thrombos Haemost 1993;69:293-5.
19. Sutor AH, Dagres N, Niederhoff H. Late form of vitamin K deficiency bleeding in Germany. Klin Padiatr 1995;207:89-97.
20. Hansen KN, Ebbesen F. Neonatal vitamin K prophylaxis in Denmark: Three years' experience with oral administration during the first three months of life compared with one oral administration at birth. Acta Paediatr 1996;85:1137-9.
21. Cornelissen EAM, Kollee LAA, van Lith TGPJ, et al. Evaluation of a daily dose of 25 μg vitamin K1 to prevent vitamin K deficiency in breast-fed infants. J Pediatr Gastroenterol Nutr 1992; 16:301-5.
22. Cornelissen EAM, Kollee LAA, De Abreu RA, et al. Prevention of vitamin K deficiency in infancy by weekly administration of vitamin K. Acta Paediatr 1993;82:656-9.