The synthesis of phosphinic acid based proteinase inhibitors

Phosphorus, Sulfur and Silicon and Related Elements

Volumn 144-146, Issue , 1999, Pages 761-764

  Hamilton, Robert ^a   Wharry, Scott ^a   Walker, Brian ^a   Walker, Brian J ^a  

^a QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

Author keywords

C2 symmetrical; HIV inhibitors; Phosphinate analogues; Serine proteinase

Indexed keywords

EID: 0033234749     PISSN: 10426507     EISSN: None     Source Type: Journal    
DOI: 10.1080/10426509908546356     Document Type: Article

References (12)

1. J. Oleksyszn and J.C. Powers, Biochemistry, 30, 485, (1991); R. Hamilton, G. Kay, R. Shute, J. Travers, B. Walker and B.J. Walker, Phosphorus, Sulphur and Silicon, 78, 127, (1993).
2. J. Oleksyszn and J.C. Powers, Biochemistry, 30, 485, (1991); R. Hamilton, G. Kay, R. Shute, J. Travers, B. Walker and B.J. Walker, Phosphorus, Sulphur and Silicon, 78, 127, (1993).
3. R.L. Stein, Ann. Rep. Med. Chem., 20, 237, (1985).
4. N. S. Samson and P. A. Bartlett, Biochemistry, 30, 2255, (1991); R. Bone, N.S. Samson P.A. Bartlett and D.A. Agard, Biochemistry, 30, 2263, (1991).
5. N. S. Samson and P. A. Bartlett, Biochemistry, 30, 2255, (1991); R. Bone, N.S. Samson P.A. Bartlett and D.A. Agard, Biochemistry, 30, 2263, (1991).
6. E.K. Baylis, C.D. Campbell and J.G. Dingwall., J. Chem. Soc., Perkin Trans. 1, 2845, (1984).
7. E.A. Boyd, M. Corless, K. James and A.C. Regan, Tetrahedron Letters, 31, 2933, (1990).
8. R. Hamilton, B. Walker and B. J. Walker, Tetrahedron Letters, 36, 4451, (1995).
9. H. Mitsuya, R. Yarchoan and S. Broder, Science, 249, 1533, (1990).
10. M. A. Navia, P.M.D. Fitzgerald, B.M. McKeever, L. Chih-Tai, J.C. Heimbach, W.K. Herber, S.S. Irving, P.L. Darke and J.P. Springer, Nature, 337, 615, (1989).
11. e.g. A. Payman, K-H. Budt, J. Spanig and D. Ruppert, Angew. Chem. Int. Ed. Engl., 32, 1720, (1993).
12. K. M. Yager, C. M. Taylor and A. B. Smyth, J. Am. Chem. Soc., 116, 9377, (1994).