The synthesis of novel modified nucleic acid monomers and their subsequent solid phase oligomerisation to give 3'-methylene phosphonate DNA (3MP)

Phosphorus, Sulfur and Silicon and Related Elements

Volumn 144-146, Issue , 1999, Pages 645-648

  Collingwood, Stephen P ^a   Douglas, Mark E ^a   Natt, Francois ^b   Pieles, Uwe ^b  

^a Novartis Institutes of Biomedical Research   (United Kingdom)

^b NOVARTIS PHARMA AG   (Switzerland)

Author keywords

Antisense; DNA; Solid phase synthesis

Indexed keywords

EID: 0033234722     PISSN: 10426507     EISSN: None     Source Type: Journal    
DOI: 10.1080/10426509908546327     Document Type: Article

References (6)

1. S M Freier, K-H Altmann, Nucleic Acids Res., 4429, 25 (1997).
2. V Tereshko, S Gryaznov, M Egli, J. Am. Chem Soc, 269, 120, (1998) and references therein.
3. U Heinemann, L N Rudolph, C Alings, M Morr, W Heikens, R Frank, H Blocker, Nucleic Acids Res. 427, 19, (1991) and references therein.
4. B Froehler in Protocols for Oligonucleotides and Analogues Ed S Agrawal, Humana, (1993).
5. S P Collingwood, A D Baxter, Synlett, 703 (1995).
6. Y S Sanghvi, R Bharadwaj, F Debart, A DeMesmaeker, Synthesis, 1163, (1994).