2β-Carbomethoxy-3β-(4- and 2-[18F]fluoromethylphenyl)tropanes: Specific probes for in vivo quantification of central dopamine transporter sites

Nuclear Medicine and Biology

Volumn 26, Issue 8, 1999, Pages 897-903

  Stout, David ^a   Petric, Andrej ^b   Satyamurthy, N ^a   Nguyen, Quan ^a   Huang, Sung Cheng ^a   Namavari, Mohammad ^a   Barrio, Jorge R ^a  

^a Division of Nuclear Medicine   (United States)

^b UNIVERSITY OF LJUBLJANA   (Slovenia)

Author keywords

2 Carbomethoxy 3 (2 18F fluoromethylphenyl)tropane (o FWIN); 2 Carbomethoxy 3 (4 18F fluoromethylphenyl)tropane (p FWIN); Central dopaminergic system; Dopamine transporter; Positron emission tomography

Indexed keywords

BENZENE DERIVATIVE; CARBON 11; DOPAMINE TRANSPORTER; FLUORINE 18; FLUORINE DERIVATIVE; TROPANE DERIVATIVE; (1R (EXO,EXO)) 3 (4 FLUOROPHENYL) 8 METHYL 8 AZABICYCLO(3.2.1)OCTANE 2 CARBOXYLIC ACID, METHYL ESTER; (1R-(EXO,EXO))-3-(4-FLUOROPHENYL)-8-METHYL-8- AZABICYCLO(3.2.1)OCTANE-2-CARBOXYLIC ACID, METHYL ESTER; 2 CARBOMETHOXY 3 (2 FLUOROMETHYLPHENYL)TROPANE; 2 CARBOMETHOXY 3 (4 FLUOROMETHYLPHENYL)TROPANE; 2-CARBOMETHOXY-3-(2-FLUOROMETHYLPHENYL)TROPANE; 2-CARBOMETHOXY-3-(4-FLUOROMETHYLPHENYL)TROPANE; CARRIER PROTEIN; COCAINE; DOPAMINE RECEPTOR; DOPAMINE UPTAKE INHIBITOR; DRUG DERIVATIVE; LIGAND; MEMBRANE PROTEIN; NERVE PROTEIN; NORADRENALIN; RADIOPHARMACEUTICAL AGENT; SEROTONIN;

ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BINDING KINETICS; BRAIN REGION; DOPAMINERGIC SYSTEM; DRUG UPTAKE; HALF LIFE TIME; LIGAND BINDING; MONKEY; NONHUMAN; RAT; ANIMAL; BRAIN; BRAIN LEVEL; CERCOPITHECUS; COMPUTER ASSISTED EMISSION TOMOGRAPHY; IMAGE PROCESSING; METABOLISM; SCINTISCANNING; SPRAGUE DAWLEY RAT; SYNTHESIS;

ANIMALS; BRAIN; BRAIN CHEMISTRY; CARRIER PROTEINS; CERCOPITHECUS AETHIOPS; COCAINE; DOPAMINE PLASMA MEMBRANE TRANSPORT PROTEINS; DOPAMINE UPTAKE INHIBITORS; IMAGE PROCESSING, COMPUTER-ASSISTED; LIGANDS; MEMBRANE GLYCOPROTEINS; MEMBRANE TRANSPORT PROTEINS; NERVE TISSUE PROTEINS; NOREPINEPHRINE; RADIOPHARMACEUTICALS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, DOPAMINE; SEROTONIN; TOMOGRAPHY, EMISSION-COMPUTED; TROPANES;

EID: 0033233303     PISSN: 09698051     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0969-8051(99)00073-6     Document Type: Article

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