Haplotypes of the β-globin gene as prognostic factors in Sickle-Cell Disease

Eastern Mediterranean Health Journal

Volumn 5, Issue 6, 1999, Pages 1154-1158

  El Hazmi, M A F ^a   Warsy, A S ^b   Bashir, N ^c   Beshlawi, A ^d   Hussain, I R ^e   Temtamy, S ^e   Qubaili, F ^f  

^a KING KHALID UNIVERSITY HOSPITAL   (Saudi Arabia)

^b KING SAUD UNIVERSITY   (Saudi Arabia)

^c JORDAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Jordan)

^d CAIRO UNIVERSITY   (Egypt)

^e NATIONAL RESEARCH CENTRE   (Egypt)

^f DAMASCUS UNIVERSITY   (Syrian Arab Republic)

Author keywords

[No Author keywords available]

Indexed keywords

GLOBIN;

ARTICLE; CLASSIFICATION; COMPARATIVE STUDY; DEMOGRAPHY; EGYPT; GENE FREQUENCY; GENETIC POLYMORPHISM; GENETIC SCREENING; GENETIC VARIABILITY; GENETICS; HAPLOTYPE; HEALTH SURVEY; HETEROZYGOTE; HOMOZYGOTE; HOSPITALIZATION; JORDAN; PROGNOSIS; RESTRICTION MAPPING; SAUDI ARABIA; SICKLE CELL ANEMIA; STATISTICS; SYRIAN ARAB REPUBLIC;

ANEMIA, SICKLE CELL; EGYPT; GENE FREQUENCY; GENETIC SCREENING; GLOBINS; HAPLOTYPES; HETEROZYGOTE; HOMOZYGOTE; JORDAN; POLYMORPHISM, GENETIC; POPULATION SURVEILLANCE; PROGNOSIS; RESIDENCE CHARACTERISTICS; RESTRICTION MAPPING; SAUDI ARABIA; SEVERITY OF ILLNESS INDEX; SYRIA; VARIATION (GENETICS);

EID: 0033232139     PISSN: 10203397     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. Deisseroth A et al. Chromosomal localization of human β-globin gene on human chromosome 11 in somatic cell hybrids. Proceedings of the National Academy of Sciences of the United States of America, 1978, 75:1456-60.
2. Fritsch EF et al. Molecular cloning and characterization of the human β-like globin gene cluster. Cell, 1980, 19:959-73.
3. Maniatis T et al. The molecular genetics of human hemoglobins. Annual review of genetics, 1980, 14:145-78.
4. Key YM, Dozy AM. Polymorphism of DNA sequence adjacent to the human β-globin structural gene: relationship to sickle mutation. Proceedings of the National Academy of Sciences of the United States of America, 1978, 75:5631-5.
5. Jeffreys AJ. DNA sequence variants in the G gamma-, A gamma-, delta- and beta-globin genes of man. Cell, 1979, 18:1-10.
6. Antonarakis SE et al. DNA polymorphism and molecular pathology of the human globin gene clusters. Human genetics, 1985, 69:1-14.
7. Antonarakis SE et al. β-thalassemia in American blacks: novel mutations in the "TATA" box and an acceptor splice site. Proceedings of the National Academy of Sciences of the United States of America, 1984 81:1154-8.
8. Kan YW et al. Polymorphism of DNA sequence in the β-globin gene region. Application to prenatal diagnosis of β 0 thalassemia in Sardinia. New England journal of medicine, 1980, 302:185-8.
9. Serjeant GR. The clinical features of sickle-cell disease. Amsterdam, North-Holland Publishing, 1974.
10. Perrine RP et al. Natural history of sickle-cell anaemia in Saudi Arabs. A study of 270 subjects. Annals of internal medicine, 1978, 88:1-6.
11. Pembrey ME et al. Foetal haemoglobin production and the sickle gene in the oases of eastern Saudi Arabia. British journal of haematology, 1978, 40:415-29.
12. El-Hazmi MAF, Warsy AS. On the nature of sickle-cell disease in the south-western province of Saudi Arabia. Acta haematologica, 1986, 76:212-6.
13. Wainscoat JS et al. A genetic marker for elevated levels of haemoglobin F in homozygous sickle-cell disease? British journal of haematology, 1985, 60:261-8.
14. Miller BA et al. Molecular analysis of the high-hemoglobin-F phenotype in Saudi Arabian sickle-cell anemia. New England journal of medicine, 1987, 316:244-50.
15. Marengo-Rowe AJ. Rapid electrophoresis quantitation of haemoglobins on cellulose acetate. Journal of clinical pathology, 1965, 18:790-2.
16. Robinson AR et al. A new technique for differentiation of haemoglobin. Journal of laboratory and clinical medicine, 1957, 50:745-52.
17. Betke K et al. Estimation of small percentage of foetal haemoglobins. Nature, 1959, 184:1877-8.
18. Kunkel LM et al. Analysis of human Y-chromosome-specific reiterated DNA in chromosome variants. Proceedings of the National Academy of Sciences of the United States of America, 1977, 74:1245-9.
19. Southern EM. Detection of specific sequences among DNA fragments separated by gel electrophoresis. Journal of molecular biology, 1975, 98:503-17.
20. Sutton M et al. Polymerase chain reaction amplification applied to the determination of β-like globin gene cluster haplotypes. American journal of hematology, 1989, 32:66-9.