Cytotoxic briarane diterpenes from a gorgonacean Briareum sp.

Heterocycles

Volumn 51, Issue 11, 1999, Pages 2619-2625

  Iwagawa, Tetsuo ^a   Takayama, Keita ^a   Okamura, Hiroaki ^a   Nakatani, Munehiro ^a   Doe, Matsumi ^b   Takemura, Kaoru ^c   Shiro, Motoo ^d  

^a KAGOSHIMA UNIVERSITY   (Japan)

^b Osaka Prefecture University   (Japan)

^c Sankei Kagaku Co Ltd   (Japan)

^d RIGAKU CORPORATION   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CORAL; CYTOTOXIC AGENT; DITERPENE; HYDROXYL GROUP; UNCLASSIFIED DRUG; VIOLIDE J; VIOLIDE K; VIOLIDE L; VIOLIDE M;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG ISOLATION; DRUG SCREENING; DRUG STRUCTURE; MOLECULAR MODEL; NONHUMAN; STRUCTURE ANALYSIS;

EID: 0033231297     PISSN: 03855414     EISSN: None     Source Type: Journal    
DOI: 10.3987/COM-99-8651     Document Type: Article

References (6)

1. New briarane diterpenes from Briareum sp., collected at Bonotsu, Kagoshima prefecture. 3. For part 2. see: T. Iwagawa, K. Takayama H. Okamura, M. Nakatani, and M. Doye Heterocyles, 1999, 51, 1653.
2. J.-H. Sheu, P.-J. Sung, L.-H. Huang, S.-F. Lee, T. Wu, B.-Y. Duh, C.-Y. Chang, L.-S. Fang, K. Soong, and T.-J. Lee, J. Nat. Prod., 1996, 59, 935. and the references cited therein.
3. T. Iwagawa, N. Takenoshita, H. Okamura, M. Nakatani, M. Doye, K. Shibata, M. Shiro, Heterocyles, 1998, 48, 123.
4. A. Altomare, M. C. Burla, M. Camalli, M. Cascarano, C. Giacovazzo, A. Guagliardi, and G. Polidori, J. Appl. Cryst., 1994, 27, 435.
5. P. T. Beurskens, G. Admiraal, G. Beurskens, W. P. Bosman, R. de Gelder, R. Israel, and J. M. M. Smits, The DIRDIF-94 program system, Tchnical Report of the Crystallography Laboratory, University of Nijmegen, The Netherlands.
6. Cytotoxicity of compounds was evaluated by the growth of Vero and MDCK cells, with XTT (2,3-bis[2-methoxy-4-nitro-5-sulfophenyl]-2H-tetrazolium-5-carboxanilide; Sigma) method: see, D. A. Scudiero, Cancer Research, 1998, 48, 4827.