Formation of a new quinone methide intermediate during the oxidative transformation of 3,4-dihydroxyphenylacetic acids: Implication for eumelanin biosynthesis

Archives of Biochemistry and Biophysics

Volumn 371, Issue 1, 1999, Pages 98-106

  Sugumaran, Manickam ^a   Duggaraju, Padma ^a   Jayachandran, Ezhuthachan ^b   Kirk, Kenneth L ^b  

^a UNIVERSITY OF MASSACHUSETTS BOSTON   (United States)

^b NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

Homoprotocatechuate oxidation; Mechanism of melanogenesis; Quinone isomerization; Quinone methide formation

Indexed keywords

3,4 DIHYDROXYPHENYLACETIC ACID; 6 FLUORO 3,4 DIHYDROXYPHENYLACETIC ACID; EUMELANIN; MELANIN; QUINONE DERIVATIVE; QUINONE METHIDE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL BINDING; CHEMICAL REACTION KINETICS; CYCLIZATION; DOPAMINE METABOLISM; ELECTRON TRANSPORT; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HORMONE SYNTHESIS; OXIDATION; PIGMENTATION; PRIORITY JOURNAL; STRUCTURE ANALYSIS;

EID: 0033230926     PISSN: 00039861     EISSN: None     Source Type: Journal    
DOI: 10.1006/abbi.1999.1420     Document Type: Article

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