Identification of regulatory regions driving the expression of the Drosophila spalt complex at different developmental stages

Developmental Biology

Volumn 215, Issue 1, 1999, Pages 33-47

  Barrio, Rosa ^a   De Celis, José F ^b   Bolshakov, Slava ^a   Kafatos, Fotis C ^a  

^a EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Enhancer analysis; Gene regulation; Spalt

Indexed keywords

TRANSCRIPTION FACTOR; ZINC FINGER PROTEIN;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DROSOPHILA; EMBRYO; EMBRYO DEVELOPMENT; ENHANCER REGION; GENE CONTROL; HOMEOBOX; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

ANIMALIA; DROSOPHILA; HEXAPODA;

EID: 0033230824     PISSN: 00121606     EISSN: None     Source Type: Journal    
DOI: 10.1006/dbio.1999.9434     Document Type: Article

References (34)

1. Arnone M. I., Davidson E. H. The hardwiring of development: Organization and function of genomic regulatory systems. Development. 124:1997;1851-1864.
2. Ashburner M. Drosophila. A Laboratory Manual. 1989;Cold Spring Harbor Laboratory Press, New York.
3. Barrio R., Shea M. J., Carulli J., Lipkow K., Gaul U., Frömmer G., Schuh R., Jäckle H., Kafatos F. C. The spalt-related gene of Drosophila melanogaster is a member of an ancient family, defined by the adjacent, region-specific homeotic gene spalt. Dev. Genes Evol. 206:1996;315-325.
4. Basson M., Horvitz H. R. The Caenorhabditis elegans gene sem-4 controls neuronal and mesodermal cell development and encodes a zinc finger protein. Genes Dev. 10:1996;1953-1965.
5. Campbell G., Tomlinson A. Transducing the Dpp morphogen gradient in the wing of Drosophila: Regulation of Dpp targets by brinker. Cell. 96:1999;553-562.
6. Chen C. K., Kühnlein R. P., Eulenberg K. G., Vincent S., Affolter M., Schuh R. The transcription factors KNIRPS and KNIRPS RELATED control cell migration and branch morphogenesis during Drosophila tracheal development. Development. 125:1998;4959-4968.
7. de Celis J. F., Barrio R., Kafatos F. C. A gene complex acting downstream of dpp in Drosophila wing morphogenesis. Nature. 381:1996;421-424.
8. de Celis J. F., Barrio R., Kafatos F. C. Regulation of the spalt/spalt-related gene complex and its function during sensory organ development in the Drosophila thorax. Development. 126:1999;2653-2662.
9. Frei E., Schuh R., Baungartner S., Burri M., Noll M., Jurgens G., Seifert E., Nauber U., Jäckle H. Molecular characterisation of spalt, a homeotic gene required for head and tail development in the Drosophila embryo. EMBO J. 7:1988;197-204.
10. Gómez-Skarmeta J. L., Rodriguez I., Martinez C., Culi J., Ferrés-Marcó D., Beamonte D., Modolell J. Cis-regulation of achaete and scute: Shared enhancer-like elements drive their coexpression in proneural clusters of the imaginal discs. Genes Dev. 9:1995;1869-1882.
11. Harlow E., Lane D. Antibodies: A Laboratory Manual. 1988;Cold Spring Harbor Laboratory Press, New York.
12. Hollemann T., Schuh R., Pieler T., Stick R. Xenopus Xsal-1, a vertebrate homolog of the region specific homeotic gene spalt of Drosophila. Mech. Dev. 55:1986;19-32.
13. Jazwinska A., Kirov N., Wieschaus E., Roth S., Rushlow C. The Drosophila gene brinker reveals a novel mechanism of Dpp target gene regulation. Cell. 96:1999;563-573.
14. Jurgens G. Head and tail development of the Drosophila embryo involves spalt, a novel homeotic gene. EMBO J. 7:1988;189-196.
15. Kohlhase J., Schuh R., Dowe G., Kühnlein R. P., Jäckle H., Schroeder B., Schulz-Schaeffer W., Kretzschmar H. A., Köhler A., Müller U., Raab-Vetter M., Burkhardt E., Engel W., Stick R. Isolation, characterization, and organ-specific expression of two novel human zinc finger genes related to the Drosophila gene spalt. Genomics. 38:1996;291-298.
16. Kohlhase J., Wischermann A., Reichenbach H., Froster U., Engel W. Mutations in the SALL1 putative transcription factor gene cause Townes-Brocks syndrome. Nat. Genet. 18:1998;81-83.
17. Köster R., Stick R., Loosli F., Wittbrodt J. Medaka spalt acts as a target gene of hedgehog signalling. Development. 124:1997;3147-3156.
18. Kühnlein R. P., Bronner G., Taubert H., Schuh R. Regulation of Drosophila spalt gene expression. Mech. Dev. 66:1997;107-118.
19. Kühnlein R. P., Frömmer G., Friedrich M., Gonzalez-Gaitán M., Wever A., Wagner-Bernholz J. F., Gehring W. J., Jäckle H., Schuh R. spalt encodes an evolutionarily conserved zinc finger protein of novel structure which provides homeotic gene function in the head and tail region of the Drosophila embryo. EMBO J. 13:1994;168-179.
20. Kühnlein R. P., Schuh R. Dual function of the region-specific homeotic gene spalt during Drosophila tracheal system development. Development. 122:1996;2215-2223.
21. Lecuit T., Brook W. J., Ng M., Calleja M., Sun H., Cohen S. M. Two distinct mechanisms for long-range patterning by Decapentaplegic in the Drosophila wing. Nature. 381:1996;387-393.
22. Lindsley D., Zimm G. G. The Genome of Drosophila melanogaster. 1992;Academic Press, San Diego.
23. Minami M., Kinoshita N., Kamoshida Y., Tanimoto H., Tabata T. brinker is a target of Dpp in Drosophila that negatively regulates Dpp-dependent genes. Nature. 398:1999;242-246.
24. Nellen D., Burke R., Struhl G., Basler K. Direct and long range action of a DPP morphogen gradient. Cell. 85:1996;357-368.
25. Ott T., Schutz G. The mouse homolog of the region-specific homeotic gene spalt of Drosophila is expressed in the developing nervous system and in mesoderm-derived structures. Mech. Dev. 56:1996;117-128.
26. Reuter D., Kühnlein R. P., Frömmer G., Barrio R., Kafatos F. C., Jäckle H. Regulation, function and potential origin of the Drosophila gene spalt adjacent, which encodes a secreted protein expressed in the early embryo. Chromosoma. 104:1996;445-454.
27. Rubin G. M., Spradling A. C. Genetic transformation of Drosophila with transposable element vectors. Science. 218:1982;348-353.
28. Ruiz-Gómez M., Modolell J. Deletion analysis of the achaete-scute locus of Drosophila melanogaster. Genes Dev. 1:1987;1238-1246.
29. Sambrook J., Fritsch E. F., Maniatis T. Molecular Cloning. A Laboratory Manual. 1989;Cold Spring Harbor Laboratory Press, Cold Spring Harbor.
30. Sturtevant M. A., Biehs B., Marin E., Bier E. The spalt gene links the A/P compartment boundary to a linear adult structure in the Drosophila wing. Development. 124:1997;21-32.
31. Wagner-Bernholz J. T., Wilson C., Gibson G., Schuh R., Gehring W. Identification of target genes of the homeotic gene Antennapedia by enhancer detection. Genes Dev. 5:1991;2467-2480.
32. Weatherbee S., Halder G., Kim J., Hudson A., Carroll S. Ultrabithorax regulates genes at several levels of the wing-patterning hierarchy to shape the development of the Drosophila haltere. Genes Dev. 12:1998;1474-1482.
33. Wharton K. J., Crews S. CNS midline enhancers of the Drosophila slit and Toll genes. Mech. Dev. 40:1993;141-154.
34. Yuh C. H., Bolouri H., Davidson E. H. Genomic cis-regulatory logic: Experimental and computational analysis of a sea urchin gene. Science. 279:1998;1896-1902.