The assembly of β-methylene-TAD, a metabolically stable analogue of the antitumor agent TAD, by the stepwise esterification of monodeprotected methylenebis-(phosphonate) benzyl esters under Mitsunobu conditions

Bioorganic and Medicinal Chemistry Letters

Volumn 9, Issue 21, 1999, Pages 3069-3074

  Ikeda, Hisafumi ^a   Abushanab, Elie ^a   Marquez, Victor E ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 THIAZOLECARBOXAMIDE ADENINE DINUCLEOTIDE; ADENINE DERIVATIVE; ADENOSINE; ANTINEOPLASTIC AGENT; BISPHOSPHONIC ACID DERIVATIVE; TIAZOFURIN; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL REACTION; DRUG SYNTHESIS; ESTERIFICATION;

ADENOSINE DIPHOSPHATE; ANTINEOPLASTIC AGENTS; ESTERIFICATION; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR STRUCTURE; PHOSPHONIC ACIDS; PHOSPHORIC DIESTER HYDROLASES; THIAZOLES;

EID: 0033230414     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(99)00544-2     Document Type: Article

References (16)

1. Current address: Department of Synthetic Chemistry and Biological Chemistry, Faculty of Engineering, Kyoto University, Kyoto 606-8501, Japan.
2. On sabbatical leave from the University of Rhode Island.
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