Endothelial and metabolic characteristics of patients with angina and angiographically normal coronary arteries: Comparison with subjects with insulin resistance syndrome and normal controls

Journal of the American College of Cardiology

Volumn 34, Issue 5, 1999, Pages 1452-1460

  Piatti, Pier Marco ^a   Fragasso, Gabriele ^b   Monti, Lucilla D ^b   Caumo, Andrea ^c   Van Phan, Chuong ^b   Valsecchi, Giampietro ^b   Costa, Sabrina ^b   Fochesato, Elena ^a   Pozza, Guido ^b   Pontiroli, Antonio E ^a   Chierchia, Sergio ^b  

^a Divisione di Medicina Generale   (Italy)

^b VITA SALUTE SAN RAFFAELE UNIVERSITY   (Italy)

^c SAN RAFFAELE HOSPITAL   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ENDOTHELIN 1; INSULIN; NITRATE; NITRIC OXIDE; NITRITE;

ADULT; ANGINA PECTORIS; ANGIOCARDIOGRAPHY; ARTICLE; BLOOD PRESSURE; CLINICAL ARTICLE; COLORIMETRY; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; GLUCOSE INFUSION; GLUCOSE UTILIZATION; HUMAN; INSULIN RESISTANCE; INSULIN TREATMENT; INTRAVENOUS DRUG ADMINISTRATION; MALE; PLETHYSMOGRAPH; PRIORITY JOURNAL; PROTEIN EXPRESSION; SYNDROME X; VASCULAR ENDOTHELIUM; VASODILATATION;

CALORIMETRY, INDIRECT; CASE-CONTROL STUDIES; ENDOTHELIN-1; FEMALE; GLUCOSE; HUMANS; INSULIN RESISTANCE; MALE; MICROVASCULAR ANGINA; MIDDLE AGED; NITRIC OXIDE;

EID: 0033230056     PISSN: 07351097     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0735-1097(99)00379-4     Document Type: Article

References (41)

1. Kemp H.G. Left ventricular function in patients with anginal syndrome and normal coronary arteriograms. Am J Cardiol. 32:1973;375-376.
2. Cannon R.O., Camici P.G., Epstein S.E. Pathophysiological dilemma of syndrome X. Circulation. 85:1992;883-892.
3. Sax F.L., Cannon R.O., Hanson C., Epstein S.E. Impaired forearm vasodilator reserve in patients with microvascular angina. Evidence of a generalized disorder of vascular function? N Engl J Med. 317:1987;1366-1370.
4. Vrints C., Bult H., Hitter E., et al. Impaired endothelium dependent coronary vasodilatation in patients with angina pectoris and normal coronary arteriograms. J Am Coll Cardiol. 19:1992;21-31.
5. Motz W., Vogt M., Rabenay O., et al. Evidence of endothelial dysfunction in coronary resistance vessels in patients with angina pectoris and normal coronary angiograms. Am J Cardiol. 68:1991;996-1003.
6. Egashira K., Inou T., Hirooka Y., et al. Evidence of impaired endothelium-dependent coronary vasodilatation in patients with angina pectoris and normal coronary angiograms. N Engl J Med. 328:1993;1659-1664.
7. Tweddel A.C., Martin W., Hutton I. Thallium scans in syndrome X. Br Heart J. 68:1992;48-50.
8. Fragasso G., Rossetti E., Dosio F., et al. High prevalence of the thallium-201 reverse redistribution phenomenon in patients with syndrome X. Eur Heart J. 74:1966;1482-1487.
9. Kaski J.C., Elliott P.M., Salomone O., et al. Concentration of circulating plasma endothelin in patients with angina and normal coronary angiograms. Br Heart J. 74:1995;620-624.
10. Yanagisawa M., Kurihara M., Kimura S., et al. A novel potent vasoconstrictor peptide produced by vascular endothelial cell. Nature. 332:1988;411-415.
11. Botker H.E., Moller N., Ovesen P., et al. Insulin resistance in microvascular angina (syndrome X). Lancet. 342:1993;136-140.
12. Godsland I.F., Crook D., Stevenson J.C., et al. Insulin resistance syndrome in postmenopausal women with cardiological syndrome X. Br Heart J. 74:1995;47-52.
13. Dean J.D., Jones C.J.H., Hutchison S.J., et al. Hyperinsulinaemia and microvascular angina ("syndrome X"). Lancet. 337:1991;456-457.
14. Piatti P.M., Monti L.D., Conti M., et al. Hypertriglyceridemia and hyperinsulinemia are potent inducers of endothelin-1 release in humans. Diabetes. 45:1996;316-321.
15. De Fronzo R.A., Tobin J.D., Andres R. Glucose clamp technique a method for quantifying insulin secretion and resistance . Am J Physiol. 237:1979;E214-E223.
16. Alford F.P., Martin F.I.R., Pearson M.J. The significance and interpretation of mildly abnormal oral glucose tolerance. Diabetologia. 7:1971;173-180.
17. Bonora E., Moghetti P., Zancanaro C., et al. Estimates of in vivo insulin action in man comparison of insulin tolerance tests with euglycemic and hyperglycemic glucose clamp . J Clin Endocrinol Metab. 68:1989;374-378.
18. Bergman R.N., Phillips L.S., Cobelli C. Physiologic evaluation of factor controlling glucose tolerance in man measurement of insulin sensitivity and beta-cell glucose sensitivity from the response to intravenous glucose . J Clin Invest. 68:1981;1456-1467.
19. Piatti P.M., Monti L.D., Davis S.N., et al. Effects of an acute decrease in non-esterified fatty acid levels on muscle glucose utilization and forearm indirect calorimetry in lean NIDDM patients. Diabetologia. 39:1996;103-112.
20. Kelley D.E., Mitrakau A., Marsh H., et al. Skeletal muscle glycolysis, oxidation, and storage of an oral glucose load. J Clin Invest. 81:1988;1563-1571.
21. Natali A., Buzzigoli G., Taddei S., et al. Effects of insulin on hemodynamics and metabolism in human forearm. Diabetes. 39:1990;490-500.
22. Kelley D.E., Reilly J., Veneman T., Mandarino L.J. The influence of physiologic hyperinsulinemia on skeletal muscle glucose storage oxidation, and glycolysis in man. Am J Physiol. 258:1990;E923-E929.
23. Monti L.D., Sandoli E., Costa S., et al. Fluorimetric method for the measurement of intermediate metabolites (lactate, pyruvate, alanine, β-hydroxybutyrate, glycerol) using a Cobas Fara centrifugal analyzer. J Autom Chem. 15:1993;177-181.
24. + when the griess reaction is used to assay for nitrite. Anal Biochem. 224:1995;502-508.
25. Douglas A.R., Jones N.L., Reed J.W. Calculation of whole blood CO2 content. J Appl Physiol. 65:1988;473-477.
26. Baron A.D. The coupling of glucose metabolism and perfusion in human skeletal muscle. The potential role of endothelium-derived nitric oxide. Diabetes. 45:1996;S105-S109.
27. Steimberg H.O., Brechtel G., Johnson A., et al. Insulin-mediated skeletal muscle vasodilation is nitric oxide dependent. A novel action of insulin to increase nitric oxide release. J Clin Invest. 94:1994;1172-1179.
28. Laakso M., Edelman S.V., Brechtel G., Baron A.D. Impaired insulin mediated skeletal muscle blood flow in patients with NIDDM. Diabetes. 41:1992;1076-1083.
29. Laine H., Yki-Jarvinen H., Kirvela O., et al. Insulin resistance of glucose uptake in skeletal muscle cannot be ameliorated by enhancing endothelium-dependent blood flow in obesity. J Clin Invest. 101:1998;1156-1162.
30. McVeigh G.E., Brennan G.M., Johnston G.D., et al. Impaired endothelium-dependent and independent vasodilation in patients with type 2 (non-insulin-dependent) diabetes mellitus. Diabetologia. 35:1992;771-776.
31. Young M.E., Leighton B. Evidence for alterated sensitivity of the nitric oxide/cGMP signalling cascade in insulin-resistant skeletal muscle. Biochem J. 329:1998;73-79.
32. Camici P.G., Marraccini P., Lorenzoni R., et al. Coronary hemodynamics and myocardial metabolism in patients with Syndrome X response to pacing stress . J Am Coll Cardiol. 17:1991;1461-1470.
33. Utriainen T., Takala T., Luotolahti M., et al. Insulin resistance characterizes glucose uptake in skeletal muscle but not in the heart in NIDDM. Diabetologia. 41:1998;555-559.
34. Saito Y., Nakao K., Mukoyama M., Imura H. Increased plasma endothelin-1 in patients with essential hypertension. N Eng J Med. 322:1990;205.
35. Miyauchi T., Yanagishawa M., Tomizawa T., et al. Increased plasma concentration of endothelin-1 and big endothelin-1 in acute myocardial infarction. Lancet. ii:1989;53-54.
36. Lerman A., Edwards B.S., Hallet J.W., et al. Circulating and tissue endothelin immunoreactivity in advanced atherosclerosis. N Engl J Med. 325:1991;997-1001.
37. Lerman A., Burnett J.C. Jr, Higano S.T., et al. Long-term L-arginine supplementation improves small-vessel coronary endothelial function in humans. Circulation. 97:1998;2123-2128.
38. Rabinowitz D., Zierler K. Forearm metabolism in obesity and its response to intra-arterial insulin. Characterization of insulin resistance and evidence for adaptive hyperinsulinism. J Clin Invest. 41:1962;2173-2181.
39. Jackson R.A., Perry G., Rogers J., et al. Relationship between the basal glucose concentration, glucose tolerance and forearm glucose uptake in maturity-onset diabetes. Diabetes. 22:1973;751-761.
40. Jackson R.A., Advani U., Perry G., et al. Dietary diabetes. The influence of low carbohydrate diet on forearm metabolism in man. Diabetes. 22:1973;145-159.
41. Radziuk J., Inculet R. The effects of ingested and intravenous glucose on forearm uptake of glucose and glucogenic substrate in normal man. Diabetes. 32:1983;977-981.