A chronic model for intravital microscopic study of microcirculatory disorders and leukocyte/endothelial cell interaction during normotensive endotoxemia

Shock

Volumn 12, Issue 5, 1999, Pages 355-364

  Hoffmann, Johannes N ^a   Vollmar, Brigitte ^b   Inthorn, Dietrich ^a   Schildberg, Friedrich W ^a   Menger, Michael D ^b  

^a LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^b SAARLAND UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

LIPOPOLYSACCHARIDE;

ANIMAL; ARTICLE; BLOOD FLOW VELOCITY; BLOOD PRESSURE; CAPILLARY; CELL ADHESION; CHRONIC DISEASE; DISEASE MODEL; DRUG EFFECT; ENDOTOXEMIA; ENTEROBACTER INFECTION; FLUORESCENCE MICROSCOPY; HAMSTER; HEMODYNAMICS; LEUKOCYTE; METABOLISM; METHODOLOGY; MICROCIRCULATION; PATHOLOGY; PATHOPHYSIOLOGY; SEPSIS; SYRIAN HAMSTER; VASCULAR ENDOTHELIUM;

ANIMALS; BLOOD FLOW VELOCITY; BLOOD PRESSURE; CAPILLARIES; CELL ADHESION; CHRONIC DISEASE; CRICETINAE; DISEASE MODELS, ANIMAL; ENDOTHELIUM, VASCULAR; ENDOTOXEMIA; ESCHERICHIA COLI INFECTIONS; HEMODYNAMIC PROCESSES; LEUKOCYTES; LIPOPOLYSACCHARIDES; MESOCRICETUS; MICROCIRCULATION; MICROSCOPY, FLUORESCENCE; SEPSIS;

EID: 0033227938     PISSN: 10732322     EISSN: None     Source Type: Journal    
DOI: 10.1097/00024382-199911000-00005     Document Type: Article

References (34)

1. Bone RC: The pathogenesis of sepsis. Ann Intern Med 115:457-469, 1991.
2. Suffredini AF: Current prospects for the treatment of clinical sepsis. Crit Care Med 22:S12-S18, 1994.
3. van der Poll T, van Deventer SJ, Buller HR, Sturk A, ten Cate JW: Comparison of the early dynamics of coagulation activation after injection of endotoxin and tumor necrosis factor in healthy humans. Prog Clin Biol Res 367:55-60, 1991.
4. Burrell R: Human responses to bacterial endotoxin. Circ Shock 43:137-153, 1994.
5. Redl H, Schlag G, Bahrami S, Yao YM: Animal models as the basis of pharmacologic intervention in trauma and sepsis patients. World J Surg 20:487-492, 1996.
6. Fink MP, Heard SO: Laboratory models of sepsis and septic shock. J Surg Res 49:186-196, 1990.
7. McCuskey R, Urbaschek R, Urbaschek B: The microcirculation during endotoxemia. Cardio Res 32:752-763, 1996.
8. Harris NR, Russell JM, Granger DN: Mediators of endotoxin-induced leukocyte adhesion in mesenteric postcapillary venules. Circ Shock 43: 155-160, 1994.
9. Lowry SF: Cytokine mediators of immunity and inflammation. Arch Surg 128:1235-1241. 1993.
10. Lam C, Tymi K, Martin C, Sibbald W: Microvascular perfusion is impaired in a rat model of normotensive sepsis. J Clin Invest 94:2077-2083, 1994.
11. Menger MD, Lehr H-A: Scope and perspectives of intravital microscopy bridge-over from in vitro to in vivo. Immunol Today 14:(11)519-522, 1993.
12. Snyder DS, Harasawa Y, Sagawa K, Hunter WC: Effect of pentobarbital on the inotropic state of isolated canine left ventricle. Heart Vessels 8: 128-135, 1993.
13. Nolte D, Menger MD, Messmer K: Microcirculatory models of ischemia-reperfusion injury in skin and striated muscle. Int J Microcirc 15:9-16, 1995.
14. Menger MD, Steiner D, Messmer K: Microvascular ischemia-reperfusion injury in striated muscle: significance of "no reflow". Am J Physiol 263:(Heart Circ Physiol32)H1892-H1900, 1996.
15. Endrich B, Asaishi K, Goetz A, Messmer K: Technical report - a new chamber technique for microvascular studies in unaesthetized hamsters. Res Exp Med 177:125-134, 1980.
16. Menger MD, Pelikan S, Steiner D, Messmer K: Microvascular ischemia-reperfusion injury in striated muscle: significance of "reflow paradox". Am J Physiol. 263:H1901-H1906, 1992.
17. Nolte D, Zeintl H, Steinbauer M, Pickelmann S, Messmer K: Functional capillary density: an indicator of tissue perfusion? Int J Microcirc 15:244-249, 1995.
18. Nolte D, Bayer M, Lehr H-A, Becker M, Krombach F, Kreimeier U, Messmer K: Attenuation of postischemic microvascular disturbances in striated muscle by hyperosmolar saline dextran. Am J Physiol 263:(Heart Circ Physiol 32)H1411-H1416, 1992.
19. van Deventer SJ, Buller HR, ten Cate JW, Sturk A, Pauw W: Endoloxemia: an early predictor of septicemia in febrile patients. Lancet i:605-609, 1988.
20. DeLa Cadena RA, Suffredini AF, Page JD, Pixley RA, Kaufman N, Parrillo JE, Colman RW: Activation of the kallikrein-kinin system after endotoxin administration to normal human volunteers. Blood 81:3313-3317, 1993.
21. Schoeffel U, Lausen M, Ruf G, von Specht BU, Freudenberg N: The overwhelming inflammatory response and the role of endotoxin in early sepsis. Prog Clin Biol Res 308:371-376, 1989.
22. Parrillo JE: Pathogenetic mechanisms of septic shock. N Engl J Med 328:1471-1477, 1993.
23. Bick RL: Disseminated intravascular coagulation: pathophysiological mechanisms and manifestations. Semin Thromb Hemost 24:(1)3-18, 1996.
24. Johnston B, Walter UM, Issekutz AC, Issekutz TB, Anderson DC, Kubes P: Differential roles of selectins and the alpha4-integrin in acute, subacute, and chronic leukocyte recruitment in vivo. J Immunol 159:4514-4523, 1997.
25. Farquhar I, Lam C, Martin C, Sibbald W: Sepsis may decrease capillary density in the mucosa of the small bowel. Am Rev Resp Dis 147: 100a(Abstr.), 1993.
26. Walvatne CS, Johnson AS, Wojcik LJ, Cerra FB: Cardiovascular response to acute and chronic endotoxemia in awake, volume-resuscitated canine model. Shock 3:299-306, 1995.
27. Seiffge D, Kremer E: Effects of different mediators or cytokines and monoclonal antibodies to adhesion molecules on leukocyte adhesion in rat mesenteric venules. Int J Microcirc 15:301-308, 1995.
28. D'Orio V, Mendes P, Carlier P, Fatemi M, Marcelle R: Lung fluid dynamics and supply dependency of oxygen uptake during experimental endotoxic shock and volume resuscitation. Crit Care Med 19:955-962, 1991.
29. Bouskela E, Rubanyi GM: Effects of iloprost, a stable prostacyclin analog, and its combination with N-nitro-L-arginine on early events following lipopolysaccharide injection: observations in the hamster cheek pouch microcirculation. Int J Microcirc 15:170-180, 1995.
30. Uchiba M, Okajima K, Murakami K, Okabe H, Takatsuki K: Attenuation of endotoxin-induced pulmonary vascular injury by antithrombin III. Am J Physiol 270:L921-L930, 1996.
31. Grisham MB, Everse J, Janssen HF: Endotoxemia and neutrophil infiltration in vivo. Am J Physiol. 254:H1017-H1022, 1988.
32. Vollmar B, Glasz J, Senkel A, Menger MD, Messmer K: Role of leukocytes in the initial hepatic microvascular response to endotoxin. Zentralbl Chir 118:691-696, 1993.
33. Tanaka T, Tsujinaka T, Kambayashi J, Higashiyama M, Sakon M, Mori T: Sepsis model with reproducible manifestations of multiple organ failure (MOF) and disseminated intravascular coagulation (DIC). Thromb Res 54:53-61, 1989.
34. Fourrier F, Chopin C, Goudemand J, Hendrycx S, Caron C, Rime A, Marey A, Lestavel P: Septic shock, multiple organ failure, and disseminated intravascular coagulation. Compared patterns of antithrombin III, protein C, and protein S deficiencies. Chest 101:816-823, 1992.