Treatment with tumor-reactive Fab-IL-2 and Fab-staphylococcal enterotoxin A fusion proteins leads to sustained T cell activation, and long-term survival of mice with established tumors.

International journal of oncology

Volumn 15, Issue 5, 1999, Pages 873-882

  Sogaard M ^a   Ohlsson, L ^a   Kristensson, K ^a   Rosendahl, A ^a   Sjoberg, A ^a   Forsberg, G ^a   Kalland, T ^a   Dohlsten, M ^a  

^a Active Biotech Research AB   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

HYBRID PROTEIN; IMMUNOGLOBULIN F(AB) FRAGMENT; INTERLEUKIN 2; T LYMPHOCYTE ANTIGEN;

AMINO ACID SEQUENCE; ANIMAL; ARTICLE; C57BL MOUSE; CELL CULTURE; CHEMISTRY; DRUG EFFECT; ESCHERICHIA COLI; EXPERIMENTAL MELANOMA; FEMALE; GENETIC TRANSFECTION; HUMAN; IMMUNOLOGY; LUNG; LYMPHOCYTE ACTIVATION; MOLECULAR GENETICS; MOUSE; PATHOLOGY; SPLEEN; T LYMPHOCYTE; TUMOR ASSOCIATED LEUKOCYTE;

AMINO ACID SEQUENCE; ANIMALS; ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE; ESCHERICHIA COLI; FEMALE; HUMANS; IMMUNOGLOBULIN FAB FRAGMENTS; INTERLEUKIN-2; LUNG; LYMPHOCYTE ACTIVATION; LYMPHOCYTES, TUMOR-INFILTRATING; MELANOMA, EXPERIMENTAL; MICE; MICE, INBRED C57BL; MOLECULAR SEQUENCE DATA; RECOMBINANT FUSION PROTEINS; SPLEEN; T-LYMPHOCYTES; TRANSFECTION; TUMOR CELLS, CULTURED;

MLCS; MLOWN;

EID: 0033227891     PISSN: 10196439     EISSN: None     Source Type: Journal    
DOI: 10.3892/ijo.15.5.873     Document Type: Article

References (0)