Two polymorphisms within interleukin-3 (hlL3) gene detected by mismatch PCR/RFLP

Genes and Immunity

Volumn 1, Issue 2, 1999, Pages 156-158

  Nakashima, H ^a   Otsuka, T ^a   Ohba, Y ^a   Akahoshi, M ^a   Nagano, S ^a   Ogami, E ^a   Arinobu, Y ^a   Miyake, K ^a   Inoue, Y ^a   Niiro, H ^a   Kaji, Y ^a   Niho, Y ^a  

^a KYUSHU UNIVERSITY   (Japan)

Author keywords

Interleukin 3; Mismatch PCR RFLP method; Polymorphism

Indexed keywords

INTERLEUKIN 3;

ALLELE; ARTICLE; BASE MISPAIRING; GENETIC POLYMORPHISM; GENETICS; HUMAN; JAPAN; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PEDIGREE; POLYMERASE CHAIN REACTION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM;

ALLELES; BASE PAIR MISMATCH; BASE SEQUENCE; HUMANS; INTERLEUKIN-3; JAPAN; MOLECULAR SEQUENCE DATA; PEDIGREE; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH;

EID: 0033224448     PISSN: 14664879     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gene.6363636     Document Type: Article

References (10)

1. Yan Y-C, Ciarletta AB, Temple PA et al. Human IL-3 (Multi-CSF): identification by expression cloning of a novel hematopoietic growth factor related to murine IL-3. Cell 1987; 47: 3-10.
2. Otsuka T, Miyajima A, Brown N et al. Isolation and characterization of an expressible cDNA encoding human IL-3. J Immunol 1988; 7: 2288-2295.
3. Le Beau MM, Epstein ND, O'Brien SJ et al. The interleukin 3 gene is located on human chromosome 5 and is deleted in myeloid leukemias with a deletion of 5q. Proc Natl Acad Sci USA 1987; 84: 5913-5917.
4. Saltman DL, Dolganev GM, Warrington JA et al. A physical map of 15 loci on human chromosome 5q23-q33 by two-color fluorescence in situ hybridization. Genomics 1993; 16: 726-732.
5. Russ AP, Maerz W, Ruzicka V et al. Rapid detection of the hypertension-associated Met235-Thr allele of the human angiotensinogen gene. Hum Mol Genet 1993; 2: 609-610.
6. Hingorani AR, Brown JM. A simple molecular assay for the C1166 variant of the angiotensin II type 1 receptor gene. Biochem Biophys Res Comm 1995; 213: 725-729.
7. Tanaka Y, Nakashima H, Hisano C et al. Association of the interferon-7 receptor variant (Val14Met) with Systemic Lupus Erythematosus. Immunogenetics 1999; 49: 266-271.
8. Gottschalk LR, Giannola DM, Emerson SG. Molecular regulation of the human IL-3 gene: inducible T cell-restricted expression requires intact AP-1 and Elf-1 nuclear protein binding sites. J Exp Med 1993; 178: 1681-1692.
9. Shoemaker SG, Hromas R, Kaushansky K. Transcriptional regulation of interleukin 3 gene expression in T lymphocytes. Proc Natl Acad Sci USA 1990; 87: 9650-9654.
10. Jeong MC, Navani A, Oksenberg JR. Limited allelic polymorphism in the human interleukin-3 gene. Mol Cell Probes 1998; 12: 49-53.