Plasma cytokines: What we are measuring

Current Opinion in Clinical Nutrition and Metabolic Care

Volumn 2, Issue 6, 1999, Pages 475-479

  Delarche, Charlotte ^a   Chollet Martin, Sylvie ^a  

^a BICHAT HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE;

BIOASSAY; BLOOD; HUMAN; IMMUNOASSAY; REVIEW; SENSITIVITY AND SPECIFICITY;

BIOLOGICAL ASSAY; CYTOKINES; HUMANS; IMMUNOASSAY; SENSITIVITY AND SPECIFICITY;

EID: 0033218347     PISSN: 13631950     EISSN: None     Source Type: Journal    
DOI: 10.1097/00075197-199911000-00007     Document Type: Article

References (53)

1. Grimble RF. Nutritional modulation of cytokine biology. Nutrition 1998; 14:634-640. An interesting review that summarizes the modifications of the inflammatory cytokine pattern induced by nutrients.
2. Thorpe R, Wadhwa M, Bird CR, Mire-Sluis AR. Detection and measurement of cytokines. Blood 1992; 6:133-148.
3. Pugin J, Ricou B, Steinberg KP, Suter PM, Martin TR. Proinflammatory activity in bronchoalveolar lavage fluids from patients with ARDS, a prominent role for interleukin-1. Am Respir Care Med 1996; 153:1850-1856.
4. Robers M, Rensink IJ, Hack CE, Aarden LA, Reutelingsperger CP, Glatz JF, Hermens WT. A new principle for rapid immunoassay of proteins based on in situ precipitate-enhanced ellipsometry. Biophys J 1999; 76:2769-2776.
5. Bienvenu JAD, Monneret G, Gutowski M-C, Fabien N. Cytokine assays in human sera and tissues. Toxicology 1998; 129:55-61. A very complete and critical description of the different methods available for plasma cytokine assays. Some new and complementary methods for cellular and tissue detection are also discussed.
6. Redl H, Bahrami S, Leichtfried G, Schlag G. Special collection and storage tubes for blood endotoxin and cytokine measurement. Clin Chem 1992; 38:764-765.
7. Riches P, Goding R, Millar BC, Rowbottom AW. Influence of collection and separation of blood samples on plasma IL-1, IL-6 and TNF-α concentrations. J Immunol Methods 1992; 153:125-131.
8. Roux-Lembard P, Steiner G, and the Cytokine Consensus Study Group of the European Workshop for Rheumatology Research. Preliminary report on cytokine determination in human synovial fluids: a consensus study of the European Workshop for rheumatology research. Clin Exp Rheumatol 1992; 10:515-520.
9. Bienvenu J, Coulon L, Doche C, Gutowski M-C, Grau GE. Analytical performances of commercial ELISA-kits for IL-2, IL-6 and TNF-alpha. A WHO study. Eur Cytokine Netw 1993; 4:447-451.
10. Ledur A, Fitting C, David B, Hamberger C, Cavaillon J-M. Variable estimates of cytokine levels produced by commercial ELISA kits: results using international cytokine standards. J Immunol Methods 1995; 186:175-179.
11. De Kossodo S, Houba V, Grau GE, and WHO collaborative Study Group. Assaying tumor necrosis factor concentrations in human serum. A WHO international collaborative study. J Immunol Methods 1995; 182:107-114.
12. Mire-Sluis AR, Gaines Das R, Thorpe R, Participants of the Study. Implications for the assay and biological activity of interleukin-8: results of a WHO international collaborative study. J Immunol Methods 1997; 200:1-16.
13. Arakaki N, Kawakami S, Nakamura O, Ohnishi T, Miyazaki H, Ishii T, et al. Evidence for the presence of an inactive precursor of human hepatocyte growth factor in plasma and sera of patients with liver diseases. Hepatology 1995; 22:1728-1734.
14. Bailly S, Mahe Y, Ferrua B, Fay M, Tursz T, Wakasugi H, Gougerot-Pocidalo M-A. Quinolone-induced differential modification of IL-1α and IL-1β production by LPS-stimulated human monocytes. Cell Immunol 1990; 128:277-288.
15. Brailly H, Montero-Julian FA, Zuber CE, Flavetta S, Grassi J, Houssiau F, VanSnick J. Total interleukin-6 in plasma measured by immunoassay. Clin Chem 1994; 40:116-123.
16. Teodorescu M, Skosey JL, Schlesinger C, Wallman J. Covalent disulfide binding of IL-1 to α2-macroglobulin. Prog Leukoc Biol 1988; 8:209-212.
17. Crookston KP, Webb DJ, Wolf BB, Gonias SL. Classification of α2-macroglobulin-cytokine interactions based on affinity of noncovalent association in solution under apparent equilibrium conditions. J Biol Chem 1994; 269:1533-1540.
18. Kurdowska A, Carr FK, Stevens MD, Baughman RP, Martin TR. Studies on the interaction of IL-8 with human plasma α2-macroglobulin. J Immunol 1997; 158:1930-1940.
19. Dinarello CA. Interleukin-1 and interleukin-1 antagonism. Blood 1991; 77:1627-1652.
20. Nerad JL, Griffiths JK, Van der Meer JWM, Endres S, Poutsiaka DD, Keusch GT, et al. Interleukin-1β (IL-1β), IL-1 receptor antagonist, and TNFα production in whole blood. J Leukoc Biol 1992; 52:687-692.
21. Engelberts I, Stephens S, Francot GJM, Van der Linden CJ, Buurman WA. Evidence for different effects of soluble TNF-receptors on various TNF measurements in human biological fluids. Lancet 1991; 338:515-516.
22. Gaillard JP, Bataille R, Brailly H, Zuber C, Yazukawa K, Attal M, et al. Increased and highly stable levels of functional IL-6 receptor in sera of patients with monoclonal gammopathy. Eur J Immunol 1993; 23:820-824.
23. Kapadia S, Torre-Amione G, Mann DL. Pitfalls in measuring cytokines. Ann Intern Med 1994; 121:149-150.
24. Sylvester I, Yoshimura T, Sticherling M, Shröder J-M, Ceska M, Peichl P, Leonard EJ. Neutrophil attractant protein-1-immunoglobulin G immune complexes and free anti-NAP-1 antibody in normal human serum. J Clin Invest 1992; 90:471-481.
25. Svenson M, Hansen MB, Bendtzen K. Binding of cytokines to pharmaceutically prepared human immunoglobulin. J Clin Invest 1993; 92:2533-2539.
26. Hansen MB, Svenson M, Diamant M, Bendtzen K. High affinity IgG autoantibodies to IL-6 in sera of normal individuals are competitive inhibitors of IL-6 in vitro. Cytokine 1993; 5:72-80.
27. Grenier A, Dehoux M, Boutten A, Arce-Vicioso M, Durand G, Gougerot-Pocidalo M-A, Chollet-Martin S. Oncostatin M production and regulation by human polymorphonuclear neutrophils. Blood 1999; 93:1413-1421.
28. Zola H, Flego L, Wong YT, Marcardle PJ, Kenney JS. Direct demonstration of membrane IL-1α on the surface of circulating B lymphocytes and monocytes. J Immunol 1993; 150:1755-1762.
29. Darbonne WC, Rice GC, Mohler MA, Apple T, Hébert A, Valente AJ, Baker JB. Red blood, cells are a sink for interleukin 8, a leukocyte chemotaxin. J Clin Invest 1991; 88:1362-1369.
30. Marie C, Fitting C, Cheval C, Losser M-R, Carlet J, Payen D, et al. Presence of high levels of leukocyte-associated interleukin-8 upon cell activation and in patients with sepsis syndrome. Infect Immun 1997; 65:865-871.
31. Arvidson NG, Gudbjornsson B, Elfman L, Ryden AC, Totterman TH, Hallgren R. Circadian rhythm of serum interleukin-6 in rheumatoid arthritis. Ann Rheum Dis 1994; 53:521-524.
32. Cannon JG, Dinarello CA. Increased plasma interleukin-1 activity in women after ovulation. Science 1985; 227:1247-1248.
33. Chollet-Martin S, Montravers P, Gibert C, Elbim C, Desmonts J-M, Fagon J-Y, Gougerot-Pocidalo M-A. High levels of interleukin-8 in the blood and alveolar spaces of patients with pneumonia and adult respiratory distress syndrome. Infect Immun 1993; 61:4553-4559.
34. Meduri GU, Kohler G, Headley S, Tolley E, Stentz F, Postlethwaite A. Inflammatory cytokines in the BAL of patients with ARDS. Chest 1995; 108:1303-1314.
35. Donnelly SC, Strieter RM, Reid PT, Kunkel SL, Burdick MD, Armstrong I, et al. The association between mortality rates and decreased concentrations of interleukin-10 and interleukin-1 receptor antagonist in the lung fluids of patients with the adult respiratory distress syndrome. Ann Intern Med 1996; 125:191-196.
36. Pittet J-F, Mackersie RC, Martin TR, Matthay MA. Biological markers of acute lung injury: prognostic and pathogenetic significance. Am J Respir Crit Care Med 1997; 155:1187-1205.
37. Otto G, Braconier JH, Andreasson A, Svanborg C. Interleukin-6 and disease severity in patients with bacteremic and nonbacteremic febrile urinary tract infection. J Infect Dis 1999; 179:172-179.
38. Marie C, Losser M-R, Fitting C, Kermarrec N, Payen D, Cavaillon J-M. Cytokines and soluble cytokine receptors in pleural effusions from septic and nonseptic patients. Am Respir Care Med 1997; 156:1-8.
39. Segura RM, Alegre J, Varela E, Marti R, Surinach JM, Jufresa J, et al. Interleukin-8 and markers of neutrophil degranulation in pleural effusions. Am J Respir Care Med 1998; 157:1565-1572.
40. Montravers P, Chollet-Martin S, Marmuse J-P, Gougerot-Pocidalo M-A, Desmonts J-M. Lymphatic release of cytokines during acute lung injury complicating severe pancreatitis. Am Respir Care Med 1995; 152:1527-1533.
41. Matsukawa A, Yoshimura T, Maeda T, Takahashi T, Ohkawara S, Yoshinaga M. Analysis of the cytokine network among tumor necrosis factor alpha, interleukin-1 beta, interleukin-8, and interleukin-1 receptor antagonist in monosodium urate crystal-induced rabbit arthritis. Lab Invest 1998; 78:559-569.
42. de Boer JH, Erick Hack C, Verhoeven AJ, Seer Baarsma G, de Jong PTVM, Rademakers AJJM, et al. Chemoattractant and neutrophil degranulation activities related to interleukin-8 in vitreous fluid in uveitis and vitreoretinal disorders. Invest Ophthalmol Vis Sci 1993; 34:3376-3385.
43. Chan C-C, Whitcup SM, Solomon D, Nussenblatt RB. Interleukin-10 in the vitreous fluid of patients with primary intraocular lymphoma. Am J Ophthalmol 1995; 120:671-673.
44. Ertel W, Kremer J-P, Kenney J, Steckholzer U, Jarrar D, Trentz O, Schildberg FW. Downregulation of proinflammatory cytokine release in whole blood from septic patients. Blood 1995; 85:1341-1347.
45. Cavaillon J-M, Marie C, Pitton C, Fitting C. The production of TNFα and IL-8 in whole blood assays are differently regulated upon activation by LPS. In: Progress in clinical and biological research, Vol. 392. Levin J, Alving CR, Munford RS, Redl H (editors). Philadelphia, PA, USA: Wiley-Liss, Inc.; 1995. pp. 433-439.
46. Yentis SM, Rowbotton AW, Riches PG. Detection of cytoplasmic IL-1β in peripheral blood mononuclear cells from intensive care unit (ICU) patients. Clin Exp Immunol 1995; 100:330-335.
47. Collins DP, Luebering BJ, Shaut DM. T-lymphocyte functionality assessed by analysis of cytokine receptor expression, intracellular cytokine expression, and femtomolar detection of cytokine secretion by quantitative flow cytometry. Cytometry 1998; 33:249-255. A very complete and new flow cytometry study of six cytokines simultaneously analysed in HIV patients. Flow cytometers allow the easy multiplexing of assays and various analyses of different aspects of cell analysis. A very good alternative to plasma assays.
48. Hagiwara E, Abbasi F, Mor G, Ishigatsubo Y, Klinman DM. Phenotype and frequency of cells secreting IL-2, IL-4, IL-6, IL-10, IFN and TNF-α in human peripheral blood. Cytokine 1995; 7:815-822.
49. Okada Y, Papp E, Klein NJ, Pierro A. Total parenteral nutrition directly impairs cytokine production after bacterial challenge. J Pediatr Surg 1999; 34:277-280. A recent study in patients with total parenteral nutrition, which suggests that whole blood cytokine production is a better marker than plasma levels.
50. Dehoux MS, Boutten A, Ostinelli J, Seta N, Dombret M-C, Crestani B, et al. Compartmentalized cytokine production within the human lung in unilateral pneumonia. Am J Respir Crit Care Med 1994; 150:710-716.
51. Kita H, Sur S, Hunt LW, Edell ES, Weiler DA, Swanson MC, et al. Cytokine production at the site of disease in chronic eosinophilic pneumonitis. Am J Respir Crit Care Med 1996; 153:1437-1441.
52. Bergeron A, Bonay M, Kambouchner M, Lecossier D, Riquet M, Soler P, et al. Cytokine patterns in tuberculous and sarcoid granulomas. J Immunol 1997; 159:3034-3043.
53. Dong W, Selgrade MK, Gilmour IM, Lange RW, Park P, Luster MI, Kari FW. Altered alveolar macrophage function in calorie-restricted rats. Am J Respir Cell Mol Biol 1998; 19:462-469.