Detection of Toxoplasma gondii soluble antigen, SAG-1 (p30), antibody and immune complex in the cerebrospinal fluid of HIV positive or negative individuals

Revista do Instituto de Medicina Tropical de Sao Paulo

Volumn 41, Issue 6, 1999, Pages 329-338

  Chaves Borges, Flávia A ^a   Souza, Maria A ^a   Silva, Deise A O ^a   Kasper, Lloyd H ^b   Mineo, José R ^a  

^a FEDERAL UNIVERSITY OF UBERLÂNDIA   (Brazil)

^b DARTMOUTH MEDICAL SCHOOL   (United States)

Author keywords

AIDS; Encephalitis; Human cerebrospinal fluid; SAG 1 (p30) antigen; T. gondii

Indexed keywords

IMMUNOGLOBULIN G; MEMBRANE ANTIGEN; PARASITE ANTIGEN; PROTOZOAL PROTEIN; PROTOZOON ANTIBODY; SAG1 ANTIGEN, TOXOPLASMA;

ANIMAL; ANTIGEN ANTIBODY COMPLEX; ARTICLE; BAGG ALBINO MOUSE; CEREBROSPINAL FLUID; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNOLOGY; INFANT; MOUSE; NEWBORN; RETROSPECTIVE STUDY; SENSITIVITY AND SPECIFICITY; TOXOPLASMA;

ANIMALS; ANTIBODIES, PROTOZOAN; ANTIGEN-ANTIBODY COMPLEX; ANTIGENS, PROTOZOAN; ANTIGENS, SURFACE; HIV INFECTIONS; HUMANS; IMMUNOGLOBULIN G; INFANT; INFANT, NEWBORN; MICE; MICE, INBRED BALB C; PROTOZOAN PROTEINS; RETROSPECTIVE STUDIES; SENSITIVITY AND SPECIFICITY; TOXOPLASMA;

EID: 0033217390     PISSN: 00364665     EISSN: None     Source Type: Journal    
DOI: 10.1590/S0036-46651999000600001     Document Type: Article

References (41)

1. ACEBS, M.V.; DIEZ, B.; GARCIA-RODRIGUES, J.A., VIENS, P. & CISTERNA, R. Detection of circulating antigens in the diagnosis of acute toxoplasmosis. Amer. J. trop. Med. Hyg., 51: 506-511, 1994.
2. ARAUJO, F.G. & REMINGTON, J.S. - Antigenemia in recently acquired acute toxoplasmosis. J. infect. Dis., 141: 144-150, 1980.
3. BESSIÈRES, M.H.; LE BRETON, S. & SÉGUÉLA, J.P. - Analysis by immunoblotting of Toxoplasma gondii exo-antigens and comparison with somatic antigens. Parasit. Res., 78: 222-228, 1992.
4. BROOKS, R.G.; SHARMA, S.D. & REMINGTON, J.S. - Detection of Toxoplasma gondii antigens by a dot-immunobinding technique. J. clin. Microbiol., 21: 113-116, 1985.
5. CAMARGO, M.C.V.; ANTUNES, C.M.F. & CHIARI, C.A. - Epidemiologia da infecção por Toxoplasma gondii no município de Ribeirão das Neves. MG. I. Importância dos animais domésticos como fonte de infecção do T. gondii para o homem. Rev. Soc. bras. Med. trop., 28: 211-214, 1995.
6. CAMARGO, M.E.; FERREIRA, A.W.; MINEO, J.R.; TAKIGUTI, C.K. & NAKAHARA, O. S. - Immunoglobulin G and Immunoglobulin M enzyme-linked immunosorbent assays and defined toxoplasmosis serological patterns. Infect. Immun., 21: 55-58, 1978.
7. CESBRON-DELAUW, M.F. & CAPRON, A. - Excreted/secretec antigens of Toxoplasma gondii: their origin and role in the host-parasite interaction. Res. Immunol., 144: 41-42, 1993.
8. CONTINI, C.; ROMANI, R.; MAGNO, S. & DELIA, S. - Diagnosis of Toxoplasma gondii infection in AIDS patients by a tissue-culture technique Europ. J. clin. Microbiol. infect. Dis., 14: 434-440, 1995.
9. DUPOUY-CAMET, J., SOUZA, S.L.; MASLO, C. et al. - Detection of Toxaplasma gondii in venous blood from AIDS patients by polymerase chain reaction. J. clin. Microbiol., 31: 1866-1869, 1993.
10. EGGERS, C; GROB, U.; KLINKER, H. et al. - Limited value of cerebrospinal fluid for direct detection of Toxoplasma gondii in toxoplasmic encephalitis associated with AIDS. J. Neurol., 242: 644-649, 1995.
11. FALANGOLA, M.F. & PETITO, C.K. - Choroid plexus infection in cerebral toxoplasmosis in AIDS patients. Neurology, 43: 2035-2040, 1993.
12. FLECK, D.G. - Annotation: diagnosis of Toxoplasmosis. J. clin. Path., 42: 191-193, 1989.
13. FRIEDMAN, R.D. - Comparison of four different silver-staining techniques for salivary protein detection in alkaline polyacrilamyde gels. Ann. Biochem., 126: 346-349, 1982.
14. GRINWOOD, J. & SMITH, J.E. - Toxoplasma gondii: the role of a 30-kDa surface protein in host cell invasion. Exp. Parasit., 74: 106-111, 1992.
15. GROSS, U.; ROGGENKAMP, A.; JANITSCHKE, K. & HEESEMANN, J. - Improved sensitivity of the polymerase chain reaction for detection cf Toxoplasma gondii in biological and human clinical specimens. Europ. J. clin. Microbiol. infect. Dis., 11: 33-39, 1992.
16. HAFID, J.; TRAN-MANH-SUNG, R.; RABERIN, H. et al. - Detection of circulating antigens of Toxoplasma gondii in human infection. Amor. J. trop. Med. Hyg., 52: 336-339, 1995.
17. HARLOW, E. & LANE, D. - Antibodies. New York, Cold Spring Harbor Laboratory, 1988.
18. HEDMAN, K.; LAPPALAINEN, M.; SEPPÄIÄ, I. & MÄKELÄ, O. - Recent primary Toxoplasma infection indicated by a low avidity of specific IgG. J. infect. Dis., 159: 736-740, 1989.
19. HELLERBRAND, C.; GOEBEL, E.D. & DISKO, R. - High predictive value of Toxoplasma gondii IgG antibody levels in HIV-infected patients for diagnosis of cerebral toxoplasmosis. Europ. J. clin. Microbiol. infect. Dis., 15: 869-872, 1996.
20. HERMENTIN, K.; HASSL, A.; PICHER, O. & ASPÖCK, H. - Comparison of different serotests for specific Toxoplasma IgM-antibodies (ISAGA, SPIHA, IFAT) and detection of circulating antigen in two cases of laboratory acquired Toxoplasma infection. Zbl. Bakt. Mikrobiol. Hyg., 270: 534-541, 1989.
21. HOLLIMAN, R.E. - Toxoplasmosis and the acquired immune deficiency syndrome. J. Infect., 16: 121-128, 1988.
22. HUNTER, C.A.; SUBAUSTE, C.S.; VAN CLEAVE, V.H. & REMINGTON, J.S. -Production of gamma interferon by natural killer cells from Toxoplasma gondii -infected SCID mice: regulation by interleukin-10, interleukin-12, and tumor necrosis factor alpha. Infect. Immun., 62: 2818-2824, 1994.
23. KASPER, L.H.; CRABB, J.H. & PFEFFERKORN, E.R. - Purification of a major membrane protein of T. gondii by immunoabsorption with a monoclonal antibody. J. Immunol., 130: 2407-2412, 1983.
24. KHALIFA, K.E.S.; ROTH, A.; ROTH, B.; ARASTEH, K.N. & JANITSCHKE, K. -Value of PCR for evaluating occurrence of parasitemia in immunocompromised patients with cerebral and extracerebral toxoplasmosis. J. clin. Microbiol., 32: 2813-2819, 1991.
25. LAEMLY, U.K. - Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (Lond.), 227: 680-685, 1970.
26. LEBECH, M.; LEBECH, A.M.; NELSING, S.; VUUST, J.; MATHIESEN, L. & PETERSEN, E. - Detection of Toxoplasma gondii DNA by polymerase chain reaction in cerebrospinal fluid from AIDS patients with cerebral toxoplasmosis. J. infect. Dis., 165: 982-983, 1992.
27. LETILLOIS, M.F.; LAIGLE, V.; SANTORO, S.; MICOUD, M. & CHUMPOTAZI, B.F. - Toxoplasma gondii surface antigen SAG-1 in sera of HIV-infected patients as an indicator of reactivated toxoplasmosis. Europ. J. clin. Microbiol. infect. Dis., 14: 899-903, 1995.
28. LOWRY, O.H.; ROSEBROUGH, N.J.; FARR, A.L. & RANDALL, R.J. - Protein measurement with the folin phenol reagent. J. biol. Chem., 193: 265-275, 1951.
29. LUFT, B.J. & REMINGTON, J.S. - AIDS commentary: toxoplasmic encephalitis. J. infect. Dis., 157: 1-6, 1988.
30. MINEO, J.R.; CAMARGO, M.E. & FERREIRA, A.W. - Enzyme-linked immunosorbent assay for antibodies to Toxoplasma gondii polysaccharides in human toxoplasmosis. Infect. Immun., 27: 283-287, 1980.
31. MINEO, J.R.; MCLEOD, R.; MACK, D. et al. - Antibodies to Toxoplasma gondii major surface protein (SAG-1, P30) inhibit infection of host cells and are produced in murine intestine after peroral infection. J. Immunol., 150: 3951-3964, 1993.
32. NARITA, M.; YAMADA, S.; MATSUZONO, Y. et al. - Immunoglobin G avidity testing in serum and cerebrospinal fluid for analysis of measles virus infections. Clin. Diag. Lab. Immunol., 3: 211-215, 1996.
33. POTASMAN, I.; ARAÚJO, F.G.; DESMONTS, G. & REMINGTON, J.S. - Analysis of Toxoplasma gondii antigens recognized by human sera obtained before and after acute infection. J. infect. Dis., 154: 650-657, 1986.
34. POTASMAN, I.; RESNICK, L.; LUFT, B.J. & REMINGTON, J.S. - Intrathecal production of antibodies against Toxoplasma gondii in patients with toxoplasmic encephalitis and the acquired immunodeficiency syndrome (AIDS). Ann. intern. Med., 108: 49-51, 1988.
35. RAHMAH, N. & KHAIRUL, A.A. - Comparison of three forms of antigens in the demonstration of cell-mediated immune response in murine toxoplasmosis. Biochem. biophys. Res. Commun., 189: 640-644, 1992.
36. ROWLAND, L.P.; FINK, M.E. & RUBIN, L. - Cerebrospinal fluid: blood-brain barrier, brain edema, and hydrocephalus. In: KANDEL, E.R.; SCHWARTZ, J.H. & JESSELL, T.M., ed. Principles of neural Science, 3. ed. New York, Elsevier Science, 1991. p. 1050-1060.
37. VAN KNAPEN, F. & PANGGABEAN, S.O. - Detection of circulating antigen during acute infection with Toxoplasma gondii by enzyme-linked immunosorbent assay. J. clin. Microbiol., 6: 545-547, 1977.
38. VELGE-ROUSSEL, F.; CHARDÈS, T.; MÉVÉLEC, P. et al - Epitopic analysis of the Toxoplasma gondii major surface antigen SAG-1. Molec. Biochem. Parasit., 66: 31-38, 1094.
39. VINHAL, F.A.; PENA, J.D.O.; KATINA, J.H. et al. - Analysis of aqueous humor in ocular toxoplasmosis: detection of low avidity IgG specific to Toxoplasma gondii. Appl. Parasit., 35: 1-7, 1994.
40. WAINSTEIN, M.V.; WOLFFENBUTTEL, L.; LOPES, D.K. et al. - Sensibilidade e especificidade do diagnóstico clínico, sorológico e tomográfico da encefalite por Toxoplasma gondii na síndrome da imunodeficiência adquirida (SIDA). Rev. Soc. bras. Med. trop., 26: 571-575, 1988.
41. WEISS, L.M.; UDEM, S.A.; TANOWITZ, H. & WITTNER, M. - Western blot analysis of the antibody response of patients with AIDS and Toxoplasma encephalitis: antigenic diversity among Toxoplasma strains. J. infect. Dis., 157: 7-13, 1988.