Human DNA topoisomerase I: Quantitative analysis of the effects of camptothecin analogs and the benzophenanthridine alkaloids nitidine and 6- ethoxydihydronitidine on DNA topoisomerase I-induced DNA strand breakage

Archives of Biochemistry and Biophysics

Volumn 370, Issue 1, 1999, Pages 66-76

  Holden, Joseph A ^a   Wall, Monroe E ^b   Wani, Mansukh C ^b   Manikumar, Govindarajan ^b  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^b RTI INTERNATIONAL   (United States)

Author keywords

Camptothecin analogs; DNA topoisomerase I; Nitidine

Indexed keywords

7 ETHYL 10 HYDROXYCAMPTOTHECIN; 9 AMINOCAMPTOTHECIN; ALKALOID; BENZOPHENANTHRIDINE DERIVATIVE; CAMPTOTHECIN DERIVATIVE; DNA TOPOISOMERASE; NITIDINE; PLACENTA ENZYME; PLASMID DNA; RECOMBINANT ENZYME; TOPOTECAN;

ARTICLE; BACULOVIRUS; DNA STRAND BREAKAGE; DNA SUPERCOILING; DRUG DNA BINDING; DRUG POTENCY; DRUG TARGETING; ENZYME ACTIVITY; ENZYME PURIFICATION; GENE EXPRESSION SYSTEM; HALF LIFE TIME; HUMAN; ISOTOPE LABELING; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ASSAY;

UNIDENTIFIED BACULOVIRUS;

EID: 0033215359     PISSN: 00039861     EISSN: None     Source Type: Journal    
DOI: 10.1006/abbi.1999.1355     Document Type: Article

References (34)

1. Hsiang Y., Hertzberg R., Hecht S., Liu L. F. J. Biol. Chem. 260:1985;14873-14878.
2. Holden J. A. Ann. Clin. Lab. Sci. 27:1997;402-412.
3. Wang J. C. Annu. Rev. Biochem. 65:1996;635-692.
4. Svejstrup J. Q., Christainsen K., Anderson A. H., Lund K., Westergaard O. J. Mol. Biol. 222:1990;669-678.
5. Redinbo M. R., Stewart L., Kuhn P., Champoux J. J., Hol W. G. J. Science. 279:1998;1504-1513.
6. Fan Y., Weinstein J. N., Kohn K. W., Shi L. M., Pommier Y. J. Med. Chem. 41:1998;2216-2226.
7. Wu J., Liu L. F. Nucleic Acids Res. 25:1997;4181-4186.
8. Hsiang Y., Lihou M. G., Liu L. F. Cancer Res. 49:1989;5077-5082.
9. Sane A., Bertrand R. Cancer Res. 58:1998;3066-3072.
10. Giovanella B. D., Hinz H. R., Kozielski A. J., Stehlin J. S. J., Silber R., Potmesil M. Cancer Res. 51:1991;3052-3955.
11. Conti J. A., Kemeny N. E., Saltz L. B., Huang Y., Tong W. P., Chou C., Sun M., Pulliam S., Gonzalez C. J. Clin. Oncol. 14:1996;709-715.
12. Pitot H. C., Wender D. B., O'Connell M. J., Schroeder G., Goldberg R. M., Rubin J., Mailliard J. A., Knost J. A., Ghosh C., Kirschling R. J., Levitt R., Windschitl H. E. J. Clin. Oncol. 15:1997;2910-2919.
13. Creemers G. J., Gerrits C. J. H., Schellens J. H. M., Planting A. S. T., van der Burg M. E. L., van Beurden V. M., de Boer-Dennert M., Harteveld M., Loos W., Hudson I., Stoter G., Verweij J. J. Clin. Oncol. 14:1996;2540-2545.
14. Pazdur R., Diaz-Canton E., Ballard W. P., Bradof J. E., Graham S., Arbuck S. G., Abbruzzese J. L., Winn R. J. Clin. Oncol. 15:1997;2905-2909.
15. Saltz L. B., Kemeny N. E., Tong W., Harrison J., Berkery R., Kelsen D. P. Cancer. 80:1997;1727-1732.
16. Hann C., Evans D. L., Fertala J., Benedetti P., Bjornsti M., Hall D. J. J. Biol. Chem. 14:1998;8425-8433.
17. Florell S. R., Martinchick J. F., Holden J. A. Anticancer Res. 16:1996;3467-3474.
18. Bronstein I. B., Vorobyev S., Timofeev A., Jolles C. J., Alder S. L., Holden J. A. Oncol. Res. 8:1996;17-25.
19. Holden J. A. Methods in Molecular Biology. 1999;Humana Press. p. 213-221.
20. Wang X., Short G. F., Kingsbury W. D., Johnson R. K., Hecht S. M. Chem. Res. Toxicol. 11:1998;1352-1360.
21. Holden J. A., Rolfson D. H., Wittwer C. T. Biochemistry. 29:1990;2127-2134.
22. Wall M. E., Wani M. C., Nicholas A. W., Manikumar G., Tele C., Moore L., Truesdale A., Leitner P., Besterman J. M. J. Med. Chem. 36:1993;2689-2700.
23. Wall M. E., Wani M. C., Taylor H. J. Nat. Prod. 50:1987;1095-1099.
24. Luzzio M. J., Besterman J. M., Emerson D. L., Evans M. G., Lickey K., Leitner P. L., McIntyre G., Morton B., Myers P. L., Peel M., Cisco J. M., Sternback D. D., Tong W. Q., Truesdale A., Ewing D. E., Yuong A., Yates J. J. Med. Chem. 38:1995;395-401.
25. Holden J. A., Rolfson D. H., Low R. L. Biochim. Biophys. Acta. 1049:1990;303-310.
26. Bradford M. M. Anal. Biochem. 72:1976;248-254.
27. Jaxel C., Kohn K. W., Wani M. C., Wall M. E., Pommier Y. Cancer Res. 49:1989;1465-1469.
28. Hsiang Y., Liu L. F., Wall M. E., Wani M. C., Nicholas A. W., Manikumar G., Kirschenbaum S., Silber R., Potmesil M. Cancer Res. 49:1989;4385-4389.
29. Tanizawa A., Kohn K. W., Kohlhagen G., Leteurtre F., Pommier Y. Biochemistry. 34:1995;7200-7206.
30. Pommier Y., Kohlhagen G., Kohn K. W., Leteurtre F., Wani M. C., Wall M. E. Proc. Natl. Acad. Sci. USA. 92:1995;8861-8865.
31. Valenti M., Nieves-Neira W., Kohlhagen G., Kohn K. W., Wall M. E., Wani M. C., Pommier Y. Mol. Pharmacol. 52:1997;82-87.
32. Wang X., Wang L., Kingsbury W. D., Johnson R. K., Hecht S. M. Biochemistry. 37:1997;9399-9408.
33. Fang S., Wang L., Hecht S. M. J. Org. Chem. 58:1993;5025-5027.
34. Monin K. A., Bronstein I. B., Gaffney D. K., Holden J. A. Hum. Pathol. 30:1999;384-391.