Intercostal expiratory activity in an in vitro brainstem-spinal cord-rib preparation from the neonatal rat

Journal of Physiology

Volumn 520, Issue 1, 1999, Pages 293-302

  Iizuka, Makito ^a  

^a IBARAKI PREFECTURAL UNIVERSITY OF HEALTH SCIENCES   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

STRYCHNINE; GLYCINE RECEPTOR;

ANIMAL TISSUE; ARTICLE; BRAIN STEM; CHEMORECEPTOR; INTERCOSTAL MUSCLE; MOTOR ACTIVITY; NEWBORN; NONHUMAN; PH; PRIORITY JOURNAL; RAT; RIB; SPINAL CORD; VENTRAL ROOT; BREATHING; CELL PH; CONTROLLED STUDY; MOTOR CONTROL; MOTOR COORDINATION;

ANIMALS; ANIMALS, NEWBORN; BRAIN STEM; ELECTROMYOGRAPHY; GLYCINE AGENTS; HYDROGEN-ION CONCENTRATION; INTERCOSTAL MUSCLES; RATS; RATS, WISTAR; RECEPTORS, GLYCINE; RESPIRATORY MECHANICS; RIBS; SPINAL CORD; STRYCHNINE;

EID: 0033215199     PISSN: 00223751     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1469-7793.1999.00293.x     Document Type: Article

References (34)

1. ARITA, H., ICHIKAWA, K., KUWANA, S. & KOGO, N. (1989). Possible locations of pH-dependent central chemoreceptors: intramedullary regions with acidic shift of extracellular fluid pH during hypercapnia. Brain Research 485, 285-293.
2. BAINTON, C. R., KIRKWOOD, P. A. & SEARS, T. A. (1978). On the transmission of the stimulating effects of carbon dioxide to the muscles of respiration. Journal of Physiology 280, 249-272.
3. COHEN, A. H. & HARRIS-WARRICK, R. M. (1984). Strychnine eliminates alternating motor output during fictive locomotion in the lamprey. Brain Research 293, 164-167.
4. COWLEY, K. C. & SCHMIDT, B. J. (1995). Effects of inhibitory amino acid antagonists on reciprocal inhibitory interactions during rhythmic motor activity in the in vitro neonatal rat spinal cord. Journal of Neuraphysiology 74, 1109-1117.
5. DURON, B. & ROSE, D. (1997). The intercostal muscles. In Neural Control of the Respiratory Muscles, ed. MILLER, A. D., BIANCHI, A. L. & BISHOP, B. P., pp. 21-33. CRC Press, New York.
6. ELDRIDGE, F. L. (1971). Relationship between phrenic nerve activity and ventilation. American Journal of Physiology 221, 535-543.
7. FREGOSI, R. F. & BARTLETT, D. JR (1989). Internal intercostal nerve discharges in the cat: influence of chemical stimuli. Journal of Applied Physiology 66, 687-694.
8. FUNG, M.-L. & ST JOHN, W. M. (1995). Expiratory neural activities in gasping induced by pharyngeal stimulation and hypoxia. Respiration Physiology 100, 119-127.
9. FUNG, M.-L., WANG, W. & ST JOHN, W. M. (1994). Medullary loci critical for expression of gasping in adult rats. Journal of Physiology 480, 597-611.
10. GOSHGARIAN, H. G. & RAFOLS, J. A. (1981). The phrenic nucleus of the albino rat: a correlative HRP and Golgi study. Journal of Comparative Neurology 201, 441-456.
11. HAMADA, O., GARCIA-RILL, E. & SKINNER, R. D. (1992). Respiration in vitro: I. Spontaneous activity. Somatosensory and Motor Research 9, 313-326.
12. HARADA, Y., KUNO, M. & WANG, Y. Z. (1985). Differential effects of carbon dioxide and pH on central chemoreceptors in the rat in vitro. Journal of Physiology 368, 679-693.
13. HAYASHI, F. & LIPSKI, J. (1992). The role of inhibitory amino acids in control of respiratory motor output in an arterially perfused rat. Respiration Physiology 89, 47-63.
14. HO, S. M. (1997). Rhythmic motor activity and interlimb coordination in the developing pouch young of a wallaby (Macropus eugenii). Journal of Physiology 501, 623-636.
15. IIZUKA, M. (1998). Involvement of glycine receptors in coordination between inspiratory and expiratory motor activities in the newborn rat in vitro. Neuroscience Research 22, suppl., S163.
16. IIZUKA, M., NISHIMARU, H. & KUDO, N. (1998). Development of the spatial pattern of 5-HT-induced locomotor rhythm in the lumbar spinal cord of rat fetuses in vitro. Neuroscience Research 31, 107-111.
17. JANCZEWSKI, W. A. & AOKI, M. (1999). Expiratory activities in 1-4 day old rats. Japanese Journal of Physiology 49, suppl. (in the Press).
18. KUZUHARA, S. & CHOU, S. M. (1980). Localization of the phrenic nucleus in the rat: a HRP study. Neuroscience Letters 16, 119-124.
19. LOESCHCKE, H. H. (1982). Central chemosensitivity and the reaction theory. Journal of Physiology 332, 1-24.
20. MURAKOSHI, T. & OTSUKA, M. (1985). Respiratory reflexes in an isolated brainstem-lung preparation of the newborn rat: possible involvement of γ-aminobutyric acid and glycine. Neuroscience Letters 62, 63-68.
21. OLIVEN, A. & KELSEN, S. G. (1989). Effect of hypercapnia and PEEP on expiratory muscle EMG and shortening. Journal of Applied Physiology 66, 1408-1413.
22. ONIMARU, H., ARATA, A. & HOMMA, I. (1990). Inhibitory synaptic inputs to the respiratory rhythm generator in the medulla isolated from newborn rats. Pflügers Archiv 417, 425-432.
23. ONIMARU, H., ARATA, A. & HOMMA, I. (1997). Neuronal mechanisms of respiratory rhythm generation: an approach using in vitro preparation. Japanese Journal of Physiology 47, 385-403.
24. ONIMARU, H. & HOMMA, I. (1987). Respiratory rhythm generator neurons in medulla of brainstem-spinal cord preparation from newborn rat. Brain Research 403, 380-384.
25. PATON, J. F. R. & RICHTER, D. W. (1995). Role of fast inhibitory synaptic mechanisms in respiratory rhythm generation in the maturing mouse. Journal of Physiology 484, 505-521.
26. PELÁKOVÁ, A. & PALECEK, F. (1985). Electromyographic activity of expiratory muscles in the rat. Physiologia Bohemoslovaca 34, 333-338.
27. PIERREFICHE, O., SCHWARZACHER, S. W., BISCHOFF, A. M. & RICHTER, D. W. (1998). Blockade of synaptic inhibition within the pre-Bötzinger complex in the cat suppresses respiratory rhythm generation in vivo. Journal of Physiology 509, 245-254.
28. SMITH, J. C., GREER, J. J., LIU, G. & FELDMAN, J. L. (1990). Neural mechanisms generating respiratory pattern in mammalian brain stem-spinal cord in vitro I. Spatiotemporal patterns of motor and medullary neuron activity. Journal of Neurophysiology 64, 1149-1169.
29. ST JOHN, W. M. (1996). Medullary regions for neurogenesis of gasping: noeud vital or noeuds vitals? Journal of Applied Physiology 81, 1865-1877.
30. ST JOHN, W. M. & KNUTH, K. V. (1981). A characterization of the respiratory pattern of gasping. Journal of Applied Physiology 50, 984-993.
31. ST JOHN, W. M., ZHOU, D. & FREGOSI, R. F. (1989). Expiratory neural activities in gasping. Journal of Applied Physiology 66, 223-231.
32. SUZUE, T. (1984). Respiratory rhythm generation in the in vitro brain stem-spinal cord preparation of the neonatal rat. Journal of Physiology 354, 173-183.
33. CO2 and pH, and their role as chemostimulants in the isolated respiratory network of neonatal rats. Journal of Physiology 499, 527-542.
34. WANG, W., FUNG, M.-L., DARNALL, R. A. & ST JOHN, W. M. (1996). Characterizations and comparisons of eupnoea and gasping in neonatal rats. Journal of Physiology 490, 277-292.