A series of bioactivity-variant neurotoxins from scorpion Buthus martensii Karsch: X-ray crystal structure and functional implications

Journal of Natural Toxins

Volumn 8, Issue 3, 1999, Pages 309-325

  Wang, Da Cheng ^a  

^a INSTITUTE OF BIOPHYSICS   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BMK M1 NEUROTOXIN; BMK M4 NEUROTOXIN; BMK M8 NEUROTOXIN; INSECT PROTEIN; NEUROTOXIN; SCORPION VENOM;

AMINO ACID SEQUENCE; ANIMAL; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; COMPARATIVE STUDY; CONFERENCE PAPER; ISOLATION AND PURIFICATION; LD 50; MOLECULAR GENETICS; MOUSE; X RAY CRYSTALLOGRAPHY;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; INSECT PROTEINS; LETHAL DOSE 50; MICE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; NEUROTOXINS; SCORPION VENOMS;

ANIMALIA; BUTHUS; INVERTEBRATA; MESOBUTHUS MARTENSII; SCORPIONES;

EID: 0033213268     PISSN: 10588108     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (52)

1. Babin, D. R., Watt, D. D., Goos, S. M., and Mlejnek, R. V. (1974). Arch. Biochem. Biophys. 164, 964-706.
2. Babin, D. R., Watt, D. D., Goos, S. M., and Mlejnek, R. V. (1975). Arch. Biochem. Biophys. 166, 125-134.
3. Bougis, P., Rochat, H., and Smith, L. A. (1989). J. Biol. Chem. 264, 19259-19265.
4. Catterall, W. A. (1976). J. Biol. Chem. 251, 5528-5536.
5. Catterall, W. A. (1979). J. Gen. Physiol. 74, 357-391.
6. Catterall, W. A. (1984). Science 223, 653-661.
7. Catterall, W. A. (1992). Pharmacol. Rev. 72 (suppl.), 515-548.
8. Couraud, F., Jover, E., Dobois, J. M., and Rochat, H. (1982). J. Biol. Chem. 259, 6074-6084.
9. Darbon, H., and Angelides, K. J. (1984). J. Biol. Chem. 259, 6074-6084.
10. Delori, D., Van Rietschoten, J., and Rochat, H. (1981). Toxicon 19, 393-407.
11. Dufton, M. J., and Rochat, H. (1984). J. Mol. Evol. 20, 120-127.
12. El Ayeb, M., Bahraoui, E. M., Granier, C., and Rochat, H. (1986). Biochemistry 25, 6671-6678.
13. Fontecilla-Camps, J.-C., Almassy, R. J., Suddath, F. L., and Bugg, C. E. (1982). Toxicon 20, 1-7.
14. Fontecilla-Camps, J.-C., Almassy, R. J., Suddath, F. L., Watt, D. D., and Bugg, C. E. (1980). Proc. Natl. Acad. Sci. USA 77, 6496-6500.
15. Fontecilla-Camps, J.-C., Habersetzer-Rochat, C., and Rochat, H. (1988). Proc. Natl. Acad. Sci. USA 85, 7443-7447.
16. Gordon, D., Martin-Euclaire, M. F., Cestele, S., Kopeyan, C., Carlier, E., Benkhalifa, R., Pelhate, M., and Rochat, H. (1996). J. Biol. Chem. 271, 8034-8045.
17. Housset, D., Habersetzer-Rochat, C., Astier, J.-P., and Fontecilla-Camps, J.-C. (1994). J. Mol. Biol. 238, 88-103.
18. Hu, R. Q., Wang, M., Liu, J. N., and Lei, K. J. (1989a). Zoology Res. Sinica 10, 185-193.
19. Hu, R. Q., Wang, M., Liu, J. N., Yang, D., and Lei, K. J. (1989b). In: Proc. Internatl. Symp. on Natural Toxins, Z. N. Wang et al. (Eds.), p. 65. Sci. and Tech., Guilin.
20. Ji, Y. H., and Xu, K. (1983). Acta Biochem. Biophys. Sinica 15, 517-522.
21. Ji, Y. H., and Xu, K. (1986). Prog. Physiol. Sci. Sinica 17, 234-238.
22. Ji, Y. H., Mansuelle, P., Terakawa, S., Kopeyan, C., Yanaihara, N., Xu, K., and Rochat, H. (1996). Toxicon 34, 987-1001.
23. Ji, Y. H., Mansuelle, P., Xu, K., Granier, C., Kopeyan, C., Terakawa, S., and Rochat, H. (1989). Sci. in China B37, 42-49.
24. Jin, L., Wang, M., Zeng, Z.-H., Hu, R. Q., and Wang, D. C. (1993). Chinese Sci. Bull. 38, 561-563.
25. Jover, E., Couraud, F., and Rochat, H. (1980). Biochem. Biophys. Res. Commun. 95, 1607-1614.
26. Jover, E., Bublito, J., and Couraud, F. (1984). Biochemistry 23, 1147-1152.
27. Kharrat, R., Darbon, H., Granier, C., and Rochat, H. (1990). Toxicon 28, 509-523.
28. Kharrat, R., Darbon, H., Rochat, H., and Granier, C. (1989). Eur. J. Biochem. 181, 381-390.
29. Kraulis, P. J. (1991). J. Appl. Crystallogr. 24, 946-950.
30. Li, H.-M. (1995). Ph.D. Thesis, Institute of Biophysics, Chinese Academy of Sciences, Beijing.
31. Li, H.-M., Wang, D.-C., Zeng, Z.-H., Jin, L., and Hu, R. Q. (1996). J. Mol. Biol. 261, 415-431.
32. Li, H.-M., Jin, L., Zhao, T., Wang, M., Zhang, Y., and Wang, D.-C. (1998). Acta Cryst., Sect. D (in press).
33. Liu, J.-N., Yan, D., and Lei, K.-J. (1988). Chinese Sci. Bull. 33, 79-80.
34. Luo, H.-J., Xiong, Y.-M., Wang, M., Wang, D.-C., and Chi, C.-W. (1997). Toxicon 35, 723-731.
35. Mansuelle, P., Martin, M. F., Rochat, H., and Granier, C. (1992). Natural Toxins 1, 61-69.
36. Maranda, F., Kupeyan, C., Rochat, H., Rochat, C., and Lissitzky, S. (1970). Eur. J. Biochem. 17, 477-484.
37. Martin, M. F., and Rochat, H. (1986). Toxicon 24, 1131-1139.
38. Martin-Euclaire, M. F., and Couraud, F. (1995). In: Handbook of Neurotoxicology, L. W. Chang and R. S. Dyer (Eds.), pp. 683-716. Marcel Dekker, New York.
39. Meier, J., and Theakston, R. D. G. (1986). Toxicon 24, 395-401.
40. Possani, L. D., Martin, B. M., Svendsen, I., Rode, G. S., and Erickson, B. W. (1985). Biochem. J. 29, 739-750.
41. Rochat, H., Bernard, P., and Couraud, F. (1979). Scorpion toxins: Chemistry and mode of action. In: Advances in Cytopharmacology, B. Cecarelli and F. Clementi (Eds.), vol. 3, pp. 325-334. Raven Press, New York.
42. Rochat, H., Rochat, C., Sampieri, F., and Miranda, F. (1972). Eur. J. Biochem. 28, 381-388.
43. Sakabe, N. (1983). J. Appl. Cryst. 16, 542-547.
44. Song, D.-X. (1983). J. Biol. 1, 22-24.
45. Watt, D. D., and Simard, J. M. (1984). J. Toxicol. 3, 181-221.
46. Xiong, Y.-M., Ling, M.-H., Zhao, T., Wang, D.-C., and Chi, C.-W. (1997a). Acta Biophys. Sinica 29, 200-205.
47. Xiong, Y.-M., Ling, M.-H., Wang, D.-C., and Chi, C.-W. (1997b). Toxicon 35, 1025-1031.
48. Xiong, Y.-M., Ling, M.-H., Lan, Z.-D., Wang, D.-C., and Chi, C.-W. (1998). Toxicon (in press).
49. Zhao, B., Carson, M., Ealick, S. E., and Bugg, C. E. (1992). J. Mol. Biol. 227, 239-252.
50. Zhou, X. H., Yang, D., Zhang, J. H., Liu, C. M., and Lei, K. J. (1989). Biochem. J. 257, 509-517.
51. Zlotkin, E., Martinez, G., Rochat, H., and Miranda, F. (1976). In: Animal, Plant and Microbial Toxins, A. Ohsaka, K. Hayashi, and T. Sawai (Eds.), vol. 1, pp. 73-80. Plenum Publishing Corp., New York.
52. Zlotkin, E., Miranda, F., and Lissitzky, S. (1972). Toxicon 10, 207-210.