Acyclovir treatment prevents varicella-zoster virus replication in PBMC during viremia

New Microbiologica

Volumn 22, Issue 4, 1999, Pages 309-314

  Wolff, M H ^a   Schunemann S ^a  

^a UNIVERSITY OF WITTEN HERDECKE   (Germany)

Author keywords

Acyclovir; NASBA; PCR; Varicella zoster virus; Viremia

Indexed keywords

ACICLOVIR; ANTIVIRUS AGENT; VIRUS DNA; VIRUS RNA;

ADULT; AGED; ARTICLE; BLOOD; CHICKENPOX; CHILD; DRUG EFFECT; HERPES ZOSTER; HUMAN; ISOLATION AND PURIFICATION; MIDDLE AGED; MONONUCLEAR CELL; PHYSIOLOGY; VARICELLA ZOSTER VIRUS; VIREMIA; VIROLOGY; VIRUS REPLICATION;

ACYCLOVIR; ADULT; AGED; ANTIVIRAL AGENTS; CHICKENPOX; CHILD; DNA, VIRAL; HERPES ZOSTER; HERPESVIRUS 3, HUMAN; HUMANS; LEUKOCYTES, MONONUCLEAR; MIDDLE AGED; RNA, VIRAL; VIREMIA; VIRUS REPLICATION;

EID: 0033209984     PISSN: 11217138     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (14)

1. AL-NAKIB, W., AL-KANDARI, S., EL-KHALIK, D.M., and EL-SHIRBINY, A.M. (1983). A randomised controlled study of intravenous acyclovir (Zovirax) against placebo in adults with chickenpox. Journal of Infection, 6, 49-56.
2. ARVIN, A.M. (1996). Varicella-zoster virus. In: Fields B.N., Knipe, D.M., Howley, P.M. (eds): Fields Virology, Lippincott-Raven, Philadelphia, 2547-2585.
3. DLUGOSCH, D., EIS-HÜBINGER, A.M., KLEIM, J.P., KAISER, R., BIERLOFF, E., and SCHNEWEIS, K. (1991). Diagnosis of acute and latent varicella-zoster virus infections using the polymerase chain reaction. Journal of Medical Virology, 35, 136-141.
4. DUNKLE, L.M., ARVIN, A.M., WHITLEY, R.J., ROTBART, H.A., FEDER, H.M. JR, FELDMANN, S., GERSHON, A.A., LEVY, M.L., HAYDEN, G.F., MCGUIRT, P.V., ET AL. (1991). A controlled trial of acyclovir for chickenpox in normal children. New England Journal of Medicine, 325, 1539-1544.
5. HUFF, J.C., DRUCKER, J. L., CLEMMER, A., LASKIN O.L., CONNOR J.D., BRYSON Y.J., and BALFOUR H.H.JR. (1993). Effect of oral acyclovir on pain resolution in herpes zoster: a re-analysis. Journal of Medical Virology, (Suppl. 1), 93-96.
6. KIEVITS, T., VAN GEMEN, B., VAN STRIJP, D., SCHUKKINK, R., DIRCKS, M., ADRIAANSE, H., MALEK, L., SOOKNANAN, R., and LENS, P. (1991). NASBA isothermal enzymatic in vitro nucleic acid amplification optimized for the diagnosis of HIV-1 infection. Journal of Virological Methods, 35, 273-286.
7. MAHALINGAM, R., WELLISH, M., WOLF, W., DUELAND, A.N., COHRS, R., VAFAI, A., and GILDEN, D. (1990). Latent varicella-zoster virus DNA in human trigeminal and thoracic ganglia. New England Journal of Medicine, 323, 627-631.
8. MAINKA, C., and WOLFF, M.H. (1997). Detection of varicella zoster virus DNA in single trigeminal ganglia by polymerase chain reaction. Microbiologica, 20, 351-354.
9. MAINKA, C., FUß, B., GEIGER, H., HÖFELMAYR, H., and WOLFF, M.H. (1998). Characterization of viremia at different stages of varicella-zoster virus infection. Journal of Medical Virology, 56, 91-98.
10. NYERGES, G., MESZNER, Z., GYARMATI, E., and KERPEL-FRONIUS, S. (1988): Acyclovir prevents dissemination of varicella in immunocompromised children. Journal of Infectious Diseases, 157, 309-313.
11. PROBER, C.G., KIRK, L.E., and KEENEY, R.E. (1982). Acyclovir therapy of chickenpox in immunosuppressed children - a collaborative study. Journal of Pediatrics, 101, 622-625.
12. SAIKI, R.K., GELFAND, D.H., STOFFEL, S., SCHARF, S.J., HIGUCHI, R., HORN, G.T., MULLIS, K.B., and ERLICH, H.A. (1988). Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase. Science, 239, 487-491.
13. SCHÜNEMANN, S., MAINKA, C., and WOLFF, M.H. (1998). Subclinical reactivation of varicella-zoster virus in immunocompromised and immunocompetent individuals. Intervirology, 41, 98-102.
14. VAN DER VLIET, G.M., SCHUKKINK, R.A., VON GEMEN, B., SCHEPERS, P., and KLATSER, P.R. (1993). Nucleic acid sequence-based amplification (NASBA) for the identification of mycobacteria. Journal of General Microbiology, 139, 2423-2429.