Zona pellucida glycoprotein mZP3 produced in milk of transgenic mice is active as a sperm receptor, but can be lethal to newborns

Transgenic Research

Volumn 8, Issue 5, 1999, Pages 361-369

  Litscher, Eveline S ^a   Liu, Chengyu ^b   Echelard, Yann ^c   Wassarman, Paul M ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^c Genzyme Transgenics Corporation   (United States)

Author keywords

casein gene promoter; Early development; Milk mZP3; mZP3 gene; Transgenic mice

Indexed keywords

ACROSOME; FERTILIZATION; GENE FUSION; IN VITRO STUDY; LACTATION; MILK; MORPHOGENESIS; PHENOTYPE; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN PURIFICATION; RECOMBINANT PROTEIN; SURVIVAL; TRANSCRIPTION TERMINATION; TRANSGENIC MOUSE; WILD RELATIVE; ZONA PELLUCIDA GLYCOPROTEIN;

ACROSOME; ANIMALS; ANIMALS, NEWBORN; BLOTTING, WESTERN; CASEINS; EGG PROTEINS; FEMALE; GENETIC ENGINEERING; LACTATION; MALE; MEMBRANE GLYCOPROTEINS; MICE; MICE, TRANSGENIC; MILK; PROMOTER REGIONS (GENETICS); RECEPTORS, CELL SURFACE; RECOMBINANT PROTEINS; SPERM-OVUM INTERACTIONS; SPERMATOZOA; ZONA PELLUCIDA;

EID: 0033208346     PISSN: 09628819     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1008996612032     Document Type: Article

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