Transcriptional Inhibition of Matrix Metalloproteinase 9 (MMP-9) Activity by a c-fos/Estrogen Receptor Fusion Protein is Mediated by the Proximal AP-1 Site of the MMP-9 Promoter and Correlates with Reduced Tumor Cell Invasion

Neoplasia

Volumn 1, Issue 4, 1999, Pages 368-372

  Crowe, David L ^a   Brown, Tamara N ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

AP 1; Extracellular matrix; Invasion; Matrix metalloproteinase; Transcription factor

Indexed keywords

CHLORAMPHENICOL ACETYLTRANSFERASE; ESTRADIOL; ESTROGEN RECEPTOR; GELATINASE B; HYBRID PROTEIN; PROTEIN C FOS; TRANSCRIPTION FACTOR AP 1;

ARTICLE; BINDING SITE; CANCER INVASION; CELL CULTURE; DOWN REGULATION; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; GENETICS; HUMAN; METABOLISM; PHENOTYPE; PROMOTER REGION; SITE DIRECTED MUTAGENESIS; SQUAMOUS CELL CARCINOMA; WESTERN BLOTTING;

BINDING SITES; BLOTTING, WESTERN; CARCINOMA, SQUAMOUS CELL; CHLORAMPHENICOL O-ACETYLTRANSFERASE; DOWN-REGULATION; ESTRADIOL; HUMANS; MATRIX METALLOPROTEINASE 9; MUTAGENESIS, SITE-DIRECTED; NEOPLASM INVASIVENESS; PHENOTYPE; PROMOTER REGIONS (GENETICS); PROTO-ONCOGENE PROTEINS C-FOS; RECEPTORS, ESTROGEN; RECOMBINANT FUSION PROTEINS; TRANSCRIPTION FACTOR AP-1; TRANSCRIPTION, GENETIC; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 0033205270     PISSN: 15228002     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.neo.7900041     Document Type: Article

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