Ffect of blood flow rate on thrombogenesis in a Rabbit extracorporeal circulation model

ASAIO Journal

Volumn 45, Issue 5, 1999, Pages 478-481

  Kawai, Toshinori ^a   Annich, Gail M ^a   Meinhardt, Jürgen P ^a   Ichiba, Shingo ^a   Brant, David O ^a   Bartlett, Robert H ^a,b  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

POLYVINYLCHLORIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD FLOW; CONTROLLED STUDY; EXTRACORPOREAL CIRCULATION; FIBRINOGEN BLOOD LEVEL; FLOW RATE; NONHUMAN; RABBIT; THROMBOCYTE COUNT; THROMBOGENESIS; THROMBOGENICITY; TUBE;

ANIMALS; BLOOD FLOW VELOCITY; EXTRACORPOREAL CIRCULATION; FIBRINOGEN; PLATELET ACTIVATION; PLATELET ADHESIVENESS; RABBITS; THROMBOSIS;

EID: 0033200941     PISSN: 10582916     EISSN: None     Source Type: Journal    
DOI: 10.1097/00002480-199909000-00021     Document Type: Article

References (8)

1. Toomasian JM, Helmer GA, Zeme Ml, Oltean JN, Oram AD, Bartlett RH: Control of thrombosis in extracorporeal circulation: variations of anticoagulation. Trans ASAIO 29:206-209, 1983.
2. Plötz FB, Van Oeveren W, Aloe LS, et al: Prophylactic administration of tranexamic acid preserves platelet numbers during extracorporeal circulation in rabbits. ASAIO J 37: 417-419, 1991.
3. Plötz FB, Van Oeveren W, Aloe LS, et al: A heparin coated circuit reduces complement activation and the releases of leukocyte inflammatory mediators during extracorporeal mediators during extracorporeal circulation in a rabbit. Artif Organs 16: 366-370, 1992.
4. Friedman LI, Leonard EF: Platelet adhesion to artificial surfaces: consequences of flow, exposure time, blood condition, and surface nature. Fed Proc 30: 1641, 1971.
5. Baumgatner HR, Haudenschild: Adhesion of platelets to sub endothelium. Ann NY Acad Sci 201: 22-36, 1972.
6. Baumgatner HR: The role of blood flow in platelet adhesion, fibrin deposition, and formation of mural thrombi. Microvasc Res 5: 167-179, 1973.
7. Friedman LI, Liem H, Grabowski EF, Leonard EF, McCord CW: Inconsequentially of surface properties for initial platelet adhesion. Trans ASAIO 16: 63-73, 1970.
8. Ryu GH, Kim J, Ruggeri ZM, Han SH, Kim JG, Min BG: Effect of shear on fibrinogen absorption and its conformational change. ASAIO J 41: M384, M388, 1993.