-
1
-
-
9844261693
-
Impact of protease inhibitors on AIDS-defining events and hospitalizations in 10 French AIDS reference centres
-
Mouton Y, Alfandari S, Valette M, et al.: Impact of protease inhibitors on AIDS-defining events and hospitalizations in 10 French AIDS reference centres. AIDS 1997;11:F101-F105.
-
(1997)
AIDS
, vol.11
-
-
Mouton, Y.1
Alfandari, S.2
Valette, M.3
-
2
-
-
0030923798
-
Impact of combination therapy for HIV infection on inpatient census
-
Torres RA and Barr M: Impact of combination therapy for HIV infection on inpatient census. N Engl J Med 1997;336:1531-1532.
-
(1997)
N Engl J Med
, vol.336
, pp. 1531-1532
-
-
Torres, R.A.1
Barr, M.2
-
3
-
-
0343742642
-
Decline in deaths from AIDS due to new antiretrovirals
-
Hogg RS, O'Shaughnessy MV, Gataric N, et al.: Decline in deaths from AIDS due to new antiretrovirals. Lancet 1997;349:1294.
-
(1997)
Lancet
, vol.349
, pp. 1294
-
-
Hogg, R.S.1
O'Shaughnessy, M.V.2
Gataric, N.3
-
4
-
-
84921426368
-
AIDS deaths fell by 44%, but over 2500 HIV infections were reported in 1997
-
Anonymous: AIDS deaths fell by 44%, but over 2500 HIV infections were reported in 1997. Communicable Disease Report (CDR Rev) 1998;8:29.
-
(1998)
Communicable Disease Report (CDR Rev)
, vol.8
, pp. 29
-
-
-
5
-
-
2642709177
-
Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection
-
Palella FJ, Delaney KM, Moorman AC, et al.: Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. N Engl J Med 1998;338:853-860.
-
(1998)
N Engl J Med
, vol.338
, pp. 853-860
-
-
Palella, F.J.1
Delaney, K.M.2
Moorman, A.C.3
-
6
-
-
0030753947
-
Reduction of Kaposi's sarcoma lesions following treatment of AIDS with ritonavir
-
Conant M, Opp KM, Poretz D, and Mills RG: Reduction of Kaposi's sarcoma lesions following treatment of AIDS with ritonavir. AIDS 1997;11:1300-1301.
-
(1997)
AIDS
, vol.11
, pp. 1300-1301
-
-
Conant, M.1
Opp, K.M.2
Poretz, D.3
Mills, R.G.4
-
7
-
-
0032562002
-
Treatment of HIV-1-associated microsporidiosis and cryptosporidiosis with combination antiretroviral therapy
-
Carr A, Marriott D, Field A, Vasak E, and Cooper DA: Treatment of HIV-1-associated microsporidiosis and cryptosporidiosis with combination antiretroviral therapy. Lancet 1998;351:256-261.
-
(1998)
Lancet
, vol.351
, pp. 256-261
-
-
Carr, A.1
Marriott, D.2
Field, A.3
Vasak, E.4
Cooper, D.A.5
-
8
-
-
0032562016
-
Effect of HAART on natural history of AIDS-related opportunistic disorders
-
Sepkowitz K: Effect of HAART on natural history of AIDS-related opportunistic disorders. Lancet 1998;351:228-230.
-
(1998)
Lancet
, vol.351
, pp. 228-230
-
-
Sepkowitz, K.1
-
9
-
-
0030869269
-
Treatment with indinavir, zidovudine, and lamivudine in adults with human immunodeficiency virus infection and prior antiretroviral therapy
-
Gulick RM, Mellors JW, Havlir D, et al.: Treatment with indinavir, zidovudine, and lamivudine in adults with human immunodeficiency virus infection and prior antiretroviral therapy. N Engl J Med 1997;337:734-739.
-
(1997)
N Engl J Med
, vol.337
, pp. 734-739
-
-
Gulick, R.M.1
Mellors, J.W.2
Havlir, D.3
-
10
-
-
0442268112
-
A controlled trial of two nucleoside analogues plus indinavir in persons with human immunodeficiency virus infection and CD4 cell counts of 200 per cubic millimeter or less
-
Hammer SM, Squires KM, Hughes MD, et al.: A controlled trial of two nucleoside analogues plus indinavir in persons with human immunodeficiency virus infection and CD4 cell counts of 200 per cubic millimeter or less. N Engl J Med 1997;337:725-733.
-
(1997)
N Engl J Med
, vol.337
, pp. 725-733
-
-
Hammer, S.M.1
Squires, K.M.2
Hughes, M.D.3
-
11
-
-
0002388283
-
Incidence and predictors of virologic failure to indinavir (IDV) or/and ritonavir (RTV) in an urban health clinic
-
Abstract LB-2
-
Deeks S, Loftus R, Cohen P, Chin S, and Grant R: Incidence and predictors of virologic failure to indinavir (IDV) or/and ritonavir (RTV) in an urban health clinic. In 37th Interscience Conference on Antimicrobial Agents and Chemotherapy, Toronto, Ontario, Canada, 1997. [Abstract LB-2]
-
37th Interscience Conference on Antimicrobial Agents and Chemotherapy, Toronto, Ontario, Canada, 1997
-
-
Deeks, S.1
Loftus, R.2
Cohen, P.3
Chin, S.4
Grant, R.5
-
12
-
-
0344015847
-
Virological treatment failure of protease inhibitor therapy in an unselected cohort of HIV-infected patients
-
Fatkenheuer G, Theisen A, Rockstroh J, et al.: Virological treatment failure of protease inhibitor therapy in an unselected cohort of HIV-infected patients. AIDS 1997;11:F113-F116.
-
(1997)
AIDS
, vol.11
-
-
Fatkenheuer, G.1
Theisen, A.2
Rockstroh, J.3
-
13
-
-
0029614884
-
Drug-resistance patterns of saquinavir and other HIV proteinase inhibitors
-
Roberts NA: Drug-resistance patterns of saquinavir and other HIV proteinase inhibitors. AIDS 1995;9(Suppl. 2):S27-S32.
-
(1995)
AIDS
, vol.9
, Issue.2 SUPPL.
-
-
Roberts, N.A.1
-
14
-
-
0029806127
-
Rational approaches to resistance: Using saquinavir
-
Boucher C: Rational approaches to resistance: Using saquinavir. AIDS 1996;10(Suppl. 1):S15-S19.
-
(1996)
AIDS
, vol.10
, Issue.1 SUPPL.
-
-
Boucher, C.1
-
15
-
-
0029070347
-
Resistance of HIV type 1 to proteinase inhibitor Ro 31-8959
-
Eberle J, Bechowsky B, Rose D, et al.: Resistance of HIV type 1 to proteinase inhibitor Ro 31-8959. AIDS Res Hum Retroviruses 1995;11:671-676.
-
(1995)
AIDS Res Hum Retroviruses
, vol.11
, pp. 671-676
-
-
Eberle, J.1
Bechowsky, B.2
Rose, D.3
-
16
-
-
0028843163
-
Characterization of human immunodeficiency virus type 1 mutants with decreased sensitivity to proteinase inhibitor Ro 31-8959
-
Jacobsen H, Yasargil K, Winslow DL, et al.: Characterization of human immunodeficiency virus type 1 mutants with decreased sensitivity to proteinase inhibitor Ro 31-8959. Virology 1995;206: 527-534.
-
(1995)
Virology
, vol.206
, pp. 527-534
-
-
Jacobsen, H.1
Yasargil, K.2
Winslow, D.L.3
-
17
-
-
0030789573
-
Emergence of resistant variants of HIV in vivo during immunotherapy with the proteinase inhibitor saquinavir
-
Ives KJ, Jacobsen H, Galpin SA, et al.: Emergence of resistant variants of HIV in vivo during immunotherapy with the proteinase inhibitor saquinavir. J Antimicrob Chemother 1997;39:771-779.
-
(1997)
J Antimicrob Chemother
, vol.39
, pp. 771-779
-
-
Ives, K.J.1
Jacobsen, H.2
Galpin, S.A.3
-
18
-
-
0032568248
-
Resistance and cross-resistance with saquinavir and other HIV protease inhibitors: Theory and practice
-
Roberts NA, Craig JC, and Sheldon J: Resistance and cross-resistance with saquinavir and other HIV protease inhibitors: Theory and practice. AIDS 1998;12:453-460.
-
(1998)
AIDS
, vol.12
, pp. 453-460
-
-
Roberts, N.A.1
Craig, J.C.2
Sheldon, J.3
-
19
-
-
0344723263
-
Assessment of single and multiple-dose interactions between ritonavir and saquinavir
-
Abstract LB.B.6041
-
Hsu A, Granneman GR, Sun E, et al.: Assessment of single and multiple-dose interactions between ritonavir and saquinavir. In XIth International Conference on AIDS, Vancouver, 1996. [Abstract LB.B.6041]
-
XIth International Conference on AIDS, Vancouver, 1996
-
-
Hsu, A.1
Granneman, G.R.2
Sun, E.3
-
20
-
-
0031054507
-
Saquinavir pharmacokinetics alone and in combination with ritonavir in HIV-infected patients
-
Merry C, Barry MG, Mulcahy F, et al.: Saquinavir pharmacokinetics alone and in combination with ritonavir in HIV-infected patients. AIDS 1997;11:F29-F33.
-
(1997)
AIDS
, vol.11
-
-
Merry, C.1
Barry, M.G.2
Mulcahy, F.3
-
21
-
-
2442734991
-
Combination use of ritonavir and saquinavir in HIV-infected patients: Preliminary safety and activity data
-
Abstract Th.B.934
-
Cameron W, Sun E, Markowitz M, et al.: Combination use of ritonavir and saquinavir in HIV-infected patients: Preliminary safety and activity data. In XIth International Conference on AIDS, Vancouver, 1996. [Abstract Th.B.934]
-
XIth International Conference on AIDS, Vancouver, 1996
-
-
Cameron, W.1
Sun, E.2
Markowitz, M.3
-
23
-
-
0029644513
-
Safety and activity of saquinavir in HIV infection
-
Kitchen VS, Skinner C, Ariyoshi K, et al.: Safety and activity of saquinavir in HIV infection. Lancet 1995;345:952-955.
-
(1995)
Lancet
, vol.345
, pp. 952-955
-
-
Kitchen, V.S.1
Skinner, C.2
Ariyoshi, K.3
-
24
-
-
0009465508
-
Sustained benefit after four years of saquinavir monotherapy
-
Abstract Tu.B.2123
-
Pym AS, Churchill DR, Galpin S, et al.: Sustained benefit after four years of saquinavir monotherapy. In XIth International Conference on AIDS, Vancouver, 1996. [Abstract Tu.B.2123]
-
XIth International Conference on AIDS, Vancouver, 1996
-
-
Pym, A.S.1
Churchill, D.R.2
Galpin, S.3
-
25
-
-
0026753190
-
A microtitre format point mutation assay: Application to the detection of drug resistance in human immunodeficiency virus type-1 infected patients treated with zidovudine
-
Kaye S, Loveday C, and Tedder RS: A microtitre format point mutation assay: application to the detection of drug resistance in human immunodeficiency virus type-1 infected patients treated with zidovudine. J Med Virol 1992;37:241-246.
-
(1992)
J Med Virol
, vol.37
, pp. 241-246
-
-
Kaye, S.1
Loveday, C.2
Tedder, R.S.3
-
26
-
-
0344474694
-
A rapid method for simultaneous detection of phenotypic resistance to inhibitors of protease and reverse transcriptase in recombinant human immunodeficiency virus type 1 isolates from patients treated with antiretroviral drugs
-
Hertogs K, de Bethune MP, Miller V, et al.: A rapid method for simultaneous detection of phenotypic resistance to inhibitors of protease and reverse transcriptase in recombinant human immunodeficiency virus type 1 isolates from patients treated with antiretroviral drugs. Antimicrob Agents Chemother 1998;42:269-276.
-
(1998)
Antimicrob Agents Chemother
, vol.42
, pp. 269-276
-
-
Hertogs, K.1
De Bethune, M.P.2
Miller, V.3
-
27
-
-
0024310253
-
Multiple mutations in HIV-1 reverse transcriptase confer high level resistance to zidovudine
-
Larder BA and Kemp SD: Multiple mutations in HIV-1 reverse transcriptase confer high level resistance to zidovudine. Science 1989;246:1155-1158.
-
(1989)
Science
, vol.246
, pp. 1155-1158
-
-
Larder, B.A.1
Kemp, S.D.2
-
28
-
-
0027916595
-
Quantitative detection of HIV-1 drug resistance mutations by automated DNA sequencing
-
Larder BA, Kohli A, Kellam P, Kemp SD, Kronick M, and Henfrey RD: Quantitative detection of HIV-1 drug resistance mutations by automated DNA sequencing. Nature (London) 1993;365: 671-673.
-
(1993)
Nature (London)
, vol.365
, pp. 671-673
-
-
Larder, B.A.1
Kohli, A.2
Kellam, P.3
Kemp, S.D.4
Kronick, M.5
Henfrey, R.D.6
-
29
-
-
2442734678
-
A randomised trial comparing regimens of four RT inhibitors given together or cyclically with a standard two drug regimen: The Quattro trial
-
Abstract 701
-
Kitchen V, on behalf of the Quattro Steering Committee: A randomised trial comparing regimens of four RT inhibitors given together or cyclically with a standard two drug regimen: The Quattro trial. In 5th Conference on Retroviruses and Opportunistic infections, Chicago, 1998. [Abstract 701]
-
5th Conference on Retroviruses and Opportunistic Infections, Chicago, 1998
-
-
Kitchen, V.1
-
30
-
-
0030895312
-
Protease inhibitors in patients with HIV disease. Clinically important pharmacokinetic considerations
-
Barry M, Gibbons S, Back D, and Mulcahy F: Protease inhibitors in patients with HIV disease. Clinically important pharmacokinetic considerations. Clin Pharmacokinet 1997;32:194-209.
-
(1997)
Clin Pharmacokinet
, vol.32
, pp. 194-209
-
-
Barry, M.1
Gibbons, S.2
Back, D.3
Mulcahy, F.4
-
31
-
-
0029897059
-
Saquinavir: A review of its pharmacology and clinical potential in the management of HIV infection
-
Noble S and Faulds D: Saquinavir: A review of its pharmacology and clinical potential in the management of HIV infection. Drugs 1996;52:93-112.
-
(1996)
Drugs
, vol.52
, pp. 93-112
-
-
Noble, S.1
Faulds, D.2
-
32
-
-
2442725176
-
Trough plasma saquinavir levels in HIV-positive patients
-
Abstract 461
-
Lloyd J, Carey P, Timmins D, et al.: Trough plasma saquinavir levels in HIV-positive patients. In 6th European Conference on Clinical Aspects and Treatment of HIV Infection, Hamburg, 1997. [Abstract 461]
-
6th European Conference on Clinical Aspects and Treatment of HIV Infection, Hamburg, 1997
-
-
Lloyd, J.1
Carey, P.2
Timmins, D.3
-
33
-
-
0031949563
-
Human immunodeficiency virus type 1 protease genotypes and in vitro protease inhibitor susceptibilities of isolates from individuals who were switched to other protease inhibitors after long-term saquinavir treatment
-
Winters MA, Schapiro JM, Lawrence J, and Merigan TC: Human immunodeficiency virus type 1 protease genotypes and in vitro protease inhibitor susceptibilities of isolates from individuals who were switched to other protease inhibitors after long-term saquinavir treatment. J Virol 1998;72:5303-5306.
-
(1998)
J Virol
, vol.72
, pp. 5303-5306
-
-
Winters, M.A.1
Schapiro, J.M.2
Lawrence, J.3
Merigan, T.C.4
-
34
-
-
15444377672
-
Ordered accumulation of mutations in HIV protease confers resistance to ritonavir
-
Molla A, Korneyeva M, Gao Q, et al.: Ordered accumulation of mutations in HIV protease confers resistance to ritonavir. Nature Med 1996;2:760-766.
-
(1996)
Nature Med
, vol.2
, pp. 760-766
-
-
Molla, A.1
Korneyeva, M.2
Gao, Q.3
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