Structural analysis of a mutational hot-spot in the EcoRV restriction endonuclease: A catalytic role for a main chain carbonyl group

Nucleic Acids Research

Volumn 27, Issue 17, 1999, Pages 3438-3445

  Thomas, Mark P ^a   Brady, R Leo ^a   Halford, Stephen E ^a   Sessions, Richard B ^a   Baldwin, Geoffrey S ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CARBONYL DERIVATIVE; GLYCINE; LEUCINE; METAL ION; MUTANT PROTEIN; RESTRICTION ENDONUCLEASE;

AMINO ACID SUBSTITUTION; ARTICLE; CATALYSIS; CONTROLLED STUDY; CRYSTAL STRUCTURE; DNA CLEAVAGE; DRUG HYDROLYSIS; ENZYME ACTIVITY; MOLECULAR DYNAMICS; MUTAGENESIS; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN STRUCTURE; REACTION ANALYSIS; STEREOCHEMISTRY;

BINDING SITES; CATALYSIS; CRYSTALLOGRAPHY, X-RAY; DEOXYRIBONUCLEASES, TYPE II SITE-SPECIFIC; GLUTAMINE; MODELS, MOLECULAR; MUTATION; PHOSPHORIC ACID ESTERS; PROTEIN CONFORMATION;

EID: 0033200072     PISSN: 03051048     EISSN: None     Source Type: Journal    
DOI: 10.1093/nar/27.17.3438     Document Type: Article

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