Substitution of Arg527 and Arg531 in factor VIII associated with mild haemophilia A: Characterization in terms of subunit interaction and cofactor function

British Journal of Haematology

Volumn 106, Issue 3, 1999, Pages 792-800

  Celie, Patrick H N ^a   Van Stempvoort, Gunny ^a   Jorieux, Sylvie ^b   Mazurier, Claudine ^b   Van Mourik, Jan A ^a   Mertens, Koen ^a  

^a CENTRAL LABORATORY   (Netherlands)

^b Lab Francais de F   (France)

Author keywords

Factor IXa binding; Factor VIII mutants; Factor VIIIa stability; Factor VIIIa factor IXa complex assembly; Haemophilia A

Indexed keywords

BLOOD CLOTTING FACTOR 8; BLOOD CLOTTING FACTOR 10;

AMINO ACID SUBSTITUTION; ARTICLE; BINDING SITE; BLOOD CLOTTING; CASE REPORT; COMPLEX FORMATION; HEMOPHILIA A; HUMAN; MOLECULAR INTERACTION; PRIORITY JOURNAL; GENETICS; METABOLISM; MUTATION; PHENOTYPE;

AMINO ACID SUBSTITUTION; FACTOR VIII; FACTOR X; HEMOPHILIA A; HUMANS; MUTATION; PHENOTYPE;

EID: 0033192464     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.1999.01590.x     Document Type: Article

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