Tethering a type IB topoisomerase to a DNA site by enzyme fusion to a heterologous site-selective DNA-binding protein domain

Cancer Research

Volumn 59, Issue 15, 1999, Pages 3689-3697

  Beretta, Giovanni Luca ^a   Binaschi, Monica ^a   Zagni, Emanuela ^a   Capuani, Luisa ^a   Capranico, Giovanni ^a,b  

^a NATIONAL CANCER INSTITUTE   (Italy)

^b UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; DNA; DNA BINDING PROTEIN; DNA TOPOISOMERASE; HYBRID PROTEIN;

AMINO TERMINAL SEQUENCE; ARTICLE; CHIMERA; DNA CLEAVAGE; DNA FOOTPRINTING; ENZYME ACTIVITY; ENZYME BINDING; ENZYME KINETICS; GENE LOCUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN DOMAIN;

BINDING SITES; CONSENSUS SEQUENCE; DNA; DNA TOPOISOMERASES, TYPE I; DRUG DESIGN; FUNGAL PROTEINS; HUMANS; MODELS, BIOLOGICAL; PROTEIN BINDING; RECOMBINANT FUSION PROTEINS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SUBSTRATE SPECIFICITY; TEMPLATES, GENETIC; TRANSCRIPTION FACTORS;

EID: 0033179386     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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