Alternative promoters direct tissue-specific expression of the mouse protein phosphatase 2Cβ gene

European Journal of Biochemistry

Volumn 263, Issue 3, 1999, Pages 736-745

  Ohnishi, Motoko ^a   Chida, Naoki ^a   Kobayashi, Takayasu ^a   Wang, Hong ^a   Ikeda, Shoko ^a   Hanada, Masahito ^a   Yanagawa, Yuchio ^a   Katsura, Koji ^a   Hiraga, Akira ^a   Tamura, Shinri ^a  

^a TOHOKU UNIVERSITY   (Japan)

Author keywords

Alternative promoter; Gene structure; Mouse; Protein phosphatase 2C; Tissue specific expression

Indexed keywords

PHOSPHOPROTEIN PHOSPHATASE; PHOSPHOPROTEIN PHOSPHATASE 2C; UNCLASSIFIED DRUG;

ALTERNATIVE RNA SPLICING; ARTICLE; BINDING SITE; CONSENSUS SEQUENCE; DEVELOPMENT; DNA FLANKING REGION; EXON; GENE EXPRESSION; GENE LOCATION; HOUSEKEEPING GENE; INTRON; MOLECULAR CLONING; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; REPORTER GENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS; TATA BOX; TISSUE SPECIFICITY;

ANIMALS; BASE SEQUENCE; CARCINOMA, EMBRYONAL; CLONING, MOLECULAR; CONSENSUS SEQUENCE; CONSERVED SEQUENCE; EVOLUTION; EXONS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENES, REPORTER; GENOMIC LIBRARY; MICE; MOLECULAR SEQUENCE DATA; PHOSPHOPROTEIN PHOSPHATASE; PROMOTER REGIONS (GENETICS); RECOMBINANT FUSION PROTEINS; SACCHAROMYCES CEREVISIAE PROTEINS; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 0033178887     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1327.1999.00580.x     Document Type: Article

References (49)

1. 1. Cohen, P. (1989) The structure and regulation of protein phosphatases. Annu. Rev. Biochem. 58, 453-508.
2. 2. Mumby, M.C. & Walter, G. (1993) Protein serine/threonine phosphatases: structure, regulation, and functions in cell growth. Physiol. Rev. 73, 673-699.
3. 3. Shiozaki, K., Akhavan-niaki, H., McGowan, C.H. & Russel, P. (1994) Protein phosphatase 2C, encoded by ptcl+, is important in the heat shock response of Schizosaccharomyces pombe. Mol. Cell. Biol. 14, 3742-3751.
4. 4. Maeda, T., Wurgler-Murphy, S.M. & Saito, H. (1994) A two-component system that regulates an osmosensing MAP kinase cascade in yeast. Nature (London) 369, 242-245.
5. 5. Robinson, M.K., Zyl, W.H., Phizicky, E.M. & Broach, J.R. (1994) TPDI of Saccharomyces cerevisiae encodes a protein phosphatase 2C-like activity implicated in tRNA splicing and cell separation. Moll. Cell. Biol. 14, 3634-3645.
6. 6. Leung, J., Bouvier-Durand, M., Morris, P.C., Guerrier, D., Chefdor, F. & Giraudat, J. (1994) Arabidopsis ABA response gene ABII: features of a calcium-modulated protein phosphatase. Science 264, 1448-1452.
7. 7. Meyer, K., Leube, M.P. & Grill, E. (1994) A protein phosphatase 2C involved in ABA signal transduction in Arabidopsis thaliana. Science 264, 1452-1455.
8. 8. Chin-Sang, I.D. & Spence, A.M. (1996) Caenorhabditis elegans sex-determining protein FEM-2 is a protein phosphatase that promotes male development and interacts directly with FEM-3. Genes Dev. 10, 2314-2325.
9. 9. Moore, F., Weeks, J. & Hardie, D.G. (1991) Evidence that AMP triggers phosphorylation as well as direct allosteric activation of rat liver AMP-activated protein kinase. A sensitive mechanism to protect the cell against ATP depletion. Eur. J. Biochem. 199, 691-697.
10. 2+/calmodulin-dependent protein kinase II by protein phosphatase 2C. J. Biol. Chem. 268, 133-137.
11. 2+-dependent protein phosphatase α (type 2Cα). Mutat. Res. 362, 213-217.
12. 12. Tamura, S., Lynch, K.R., Larner, J., Fox, J., Yasui, A., Kikuchi, K., Suzuki, Y. & Tsuiki, S. (1989) Molecular cloning of rat type 2C (IA) protein phosphatase mRNA. Proc. Natl Acad. Sci. USA 86, 1796-1800.
13. 13. Wenk, J., Trompeter, H.-I., Pettrich, K.-G., Cohen, P.T.W., Cambell, D.G. & Mieskes, G. (1992) Molecular cloning and primary structure of a protein phosphatase 2C isoform. FEBS Lett. 297, 135-138.
14. 14. Travis, S.M. & Welsh, M.J. (1997) PP. 2C gamma: a human protein phosphatase with a unique acidic domain. FEBS Lett. 412, 415-419.
15. 15. Guthridge, M.A., Bellosta, P., Tavoloni, N. & Basilico, C. (1997) FIN 13, a novel growth factor-inducible serine-threonine phosphatase which can inhibit cell cycle progression. Mol. Cell. Biol. 17, 5485-5498.
16. 16. Fiscella, M., Zhang, H., Fan, S., Sakaguchi, K., Shen, S., Mercer, W.E., Vande Woude, G.F., O'Connor, P.M. & Appella, E. (1997) Wipl, a novel human protein phosphatase that is induced in response to ionizing radiation in a p53-dependent manner. Proc. Natl Acad. Sci. USA 94, 6048-6053.
17. 2+-dependent protein phosphatase β (type 2Cβ) enriched in brain and heart. Arch. Biochem. Biophys. 307, 342-349.
18. 18. Hou, E.W., Kawai, Y., Miyasaka, H. & Li, S.S.-L. (1994) Molecular cloning and expression of cDNAs encoding two isoforms of protein phosphatase 2Cβ from mouse testis. Biochem. Mol. Biol. Int. 32, 773-780.
19. 2+-dependent protein phosphatase β-4 (type 2C beta-4). Arch. Biochem. Biophys. 318, 387-393.
20. 20. Ohishi, S., Endo, M., Kohayashi, T., Terasawa, T., Murakami, T., Onoda, M., Ohnishi, M., Itoh, T., Tsuiki, S. & Tamura, S. (1992) Enhanced expression of type 2C protein phosphatase gene during myogenic differentiation of C3H10T1/2 cells. Biochem. Int. 28, 345-351.
21. 21. Nishikawa, M., Omay, S.B., Nakai, K., Kihira, H., Kobayashi, T., Tamura, S. & Shiku, H. (1995) Up-regulation of protein serine/ threonine phosphatase type 2C during 1 alpha,25-dihydroxyvitamin D3-induced monocytic differentiation of leukemic HL-60 cells. FEBS Lett. 375, 299-303.
22. 22. Kato, S., Kohayashi, T., Kusuda, K., Nishina, Y., Nishimune, Y., Yomogida, K., Yamamoto, M., Sakagami, H., Kondo, H., Ohnishi, M., Chida, N., Yanagawa, Y. & Tamura, S. (1996) Differentiation-dependent enhanced expression of protein phosphatase 2Cβ in germ cells of mouse seminiferous tubules. FEBS Lett. 396, 293-297.
23. 23. Feinberg, A.P. & Vogelstein, B. (1983) A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. Anal. Biochem. 132, 6-13.
24. 24. Sambrook, J., Fritsch, E.F. & Maniatis, T. (1989) Mapping of RNA with ribonuclease and radiolabeled RNA probes. In Molecular Cloning, 2nd edn. (Ford, N., ed.), pp. 771-778. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
25. 25. Breathnach, R. & Chambon, P. (1981) Organization and expression of eukaryotic split genes coding for proteins. Annu. Rev. Biochem. 50, 349-383.
26. 26. Shapiro, M.B. & Senapathy, P. (1987) RNA splice junctions of different classes of eukaryotes: sequence statistics and functional implications in gene expression. Nucleic Acids Res. 15, 7155-7174.
27. 27. Ohnishi, M., Nakagawara, K., Mori, M., Kobayashi, T., Kato, S., Sasahara, Y., Kusuda, K., Chida, N., Kobayashi, T., Yanagawa, Y., Hiraga, A., Takeuchi, T. & Tamura, S. (1996) Localization of the mouse protein serine/threonine phosphatase 2Cβ gene to chromosome 17E 4-5. Genomics 32, 134-136.
28. 28. Kozak, M. (1991) An analysis of vertebrate mRNA sequences: intimations of translational control. J. Cell Biol. 115, 887-903.
29. 29. Ren, H. & Stiles, G.L. (1994) Posttranscriptional mRNA processing as a mechanism for regulation of human Al adenosine receptor expression. Proc. Natl Acad. Sci. USA 91, 4864-4866.
30. 30. Rooney, R.J., Raychaudhuri, P. & Nevins, J.R. (1990) E4F and ATF, two transcription factors that recognize the same site, can be distinguished both physically and functionally: a role for E4F in E1A trans activation. Mol. Cell. Biol. 10, 5138-5149.
31. 31. Gaits, F., Shiozaki, K. & Russell, P. (1997) Protein phosphatase 2C acts independently of stress-activated kinase cascade to regulate the stress response in fission yeast. J. Biol. Chem. 272, 17873-17879.
32. 32. Kobayashi, M. & Kawakami, K. (1997) Synergism of the ATF/CRE site and GC box in the housekeeping Na,K-ATPase alpha 1 subunit gene is essential for constitutive expression. Biochem. Biophys. Res. Commun. 241, 169-174.
33. 33. Roy, N., Laflamme, G. & Raymond, V. (1992) 5′ untranslated sequences modulates rapid mRNA degradation mediated by 3′ AU-rich element in v-/c-fos recombinants. Nucleic Acids Res. 20, 5753-5762.
34. 34. Bucher, P. (1990) Weight matrix descriptions of four eukaryotic RNA polymerase II promoter elements derived from 502 unrelated promoter sequences. J. Mol. Biol. 212, 563-578.
35. 35. Alberts, B., Bray, D., Lewis, J., Raff, M., Roberts, K. & Watson, J.D. (1989) Controlling the start of transcription. In Molecular Biology of the Cell, 2nd edn. (Robertson, M., ed.), pp. 557-569. Garland Publishing, Inc., New York.
36. 36. Kadonaga, J.T., Carner, K.R., Masiarz, F.R. & Tjian, R. (1987) Isolation of cDNA encoding transcription factor Spl and functional analysis of the DNA binding domain. Cell 51, 1079-1090.
37. 37. Thiesen, H.J. & Bach, C. (1990) Target Detection Assay (TDA): a versatile procedure to determine DNA binding sites as demonstrated on SP1 protein. Nucleic Acids Res. 18, 3203-3209.
38. 38. Grange, T., Roux, J., Rigaud, G. & Pictet, R. (1991) Cell-type specific activity of two glucocorticoid responsive units of rat tyrosine aminotransferase gene is associated with multiple binding sites for C/EBP and a novel liver-specific nuclear factor. Nucleic Acids Res. 19, 131-139.
39. 39. Umek, R.M., Friedman, A.D. & McKnight, S.L. (1991) CCAAT-enhancer binding protein: a component of a differentiation switch. Science 251, 288-292.
40. 40. Harley, V.R., Lovell-Badge, R. & Goodfellow, P.N. (1994) Definition of a consensus DNA binding site for SRY. Nucleic Acids Res. 22, 1500-1501.
41. 41. Poulat, F., de Santa Barbara, P., Desclozeaux, M., Soullier, S., Moniot, B., Bounneaud, N., Boizet, B. & Berta, P. (1997) The human testis determining factor SRY binds a nuclear factor containing PDZ protein interaction domains. J. Biol. Chem. 272, 7167-7172.
42. 42. Zinkel, S.S., Pal, S.K., Szeberenyi, J. & Cooper, G.M. (1992) Identification of a negative regulatory element that inhibits c-mos transcription in somatic cells. Mol. Cell. Biol. 12, 2029-2036.
43. 43. Xu, W. & Cooper, G. (1995) Identification of a candidate c-mos repressor that restricts transcription of germ cell-specific genes. Mol. Cell. Biol. 15, 5369-5375.
44. 44. Baumhueter, S., Mendel, D.B., Conley, P.B., Kuo, C.J., Turk, C., Graves, M.K., Edwards, C.A., Courtois, G. & Crabtree, G.R. (1990) HNF-1 shares three sequence motifs with the POU domain proteins and is identical to LF-B1 and APF. Genes Dev. 4, 372-379.
45. 45. Tronche, F. & Yaniv, M. (1992) HNF1, a homeoprotein member of the hepatic transcription regulatory network. Bioessays 14, 579-587.
46. 46. Wu, G.D., Chen, L., Forslund, K. & Traber, P.G. (1994) Hepatocyte nuclear factor-1 alpha (HNF-1 alpha) and HNF-1 beta regulate transcription via two elements in an intestine-specific promoter. J. Biol. Chem. 269, 17080-17085.
47. 47. Olsen, J., Laustsen, L., Karnstrom, U., Sjostrom, H. & Noren, O. (1991) Tissue-specific interactions between nuclear proteins and the aminopeptidase N promoter. J. Biol. Chem. 266, 18089-18096.
48. 48. Landschulz., W.H., Johnson, P.F., Adashi, E.Y., Graves, B.J. & McKnight, S.L. (1988) Isolation of a recombinant copy of the gene encoding C/EBP. Genes Dev. 2, 786-800.
49. 49. Nishiyori, A., Tashiro, H., Kimura, A., Akagi, K., Yamamura, K., Mori, M. & Takiguchi, M. (1994) Determination of tissue specificity of the enhancer by combinatorial operation of tissue-enriched transcription factors. Both HNF-4 and C/EBP beta are required for liver-specific activity of the omithine transcarbamylase enhancer. J. Biol. Chem. 269, 1323-1331.