Synthesis and biological activity of annulated pyrazoles as selective COX-2 inhibitors. I

Archives of Pharmacal Research

Volumn 22, Issue 4, 1999, Pages 372-379

  Kim, Hyun Hee ^a   Park, Jae Gyu ^a   Moon, Tae Chul ^a   Chang, Hyun Wook ^a   Jahng, Yurngdong ^a  

^a Yeungnam University   (South Korea)

Author keywords

4,5 Polymethylenepyrazoles; Anti inflammatory; COX 1; COX 2 inhibitor

Indexed keywords

CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; ISOENZYME; PROSTAGLANDIN SYNTHASE; PROSTAGLANDIN SYNTHASE INHIBITOR; PYRAZOLE DERIVATIVE;

ANIMAL; ARTICLE; BAGG ALBINO MOUSE; BONE MARROW CELL; DRUG EFFECT; ENZYMOLOGY; MALE; MAST CELL; METABOLISM; MOUSE; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

ANIMALS; BONE MARROW CELLS; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; CYCLOOXYGENASE INHIBITORS; ISOENZYMES; MALE; MAST CELLS; MICE; MICE, INBRED BALB C; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; PYRAZOLES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0033175117     PISSN: 02536269     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02979060     Document Type: Article

References (16)

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