Protein kinase C activation is required for cigarette smoke-enhanced C5a-mediated release of interleukin-8 in human bronchial epithelial cells

American Journal of Respiratory Cell and Molecular Biology

Volumn 21, Issue 2, 1999, Pages 283-288

  Wyatt, Todd A ^a   Heires, A J ^b   Sanderson, S D ^b   Floreani, A A ^b  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

1 (5 ISOQUINOLINESULFONYL) 2 METHYLPIPERAZINE; ACETALDEHYDE; CALPHOSTIN C; COMPLEMENT COMPONENT C5A; ENZYME INHIBITOR; INTERLEUKIN 6; INTERLEUKIN 8; NAPHTHALENE DERIVATIVE; PROTEIN KINASE C;

ARTICLE; BIOSYNTHESIS; BRONCHUS; DOSE RESPONSE; ENZYME ACTIVATION; EPITHELIUM CELL; HUMAN; INDOOR AIR POLLUTION; METABOLISM; SECRETION; SMOKING; TIME;

1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE; ACETALDEHYDE; BRONCHI; COMPLEMENT C5A; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; ENZYME INHIBITORS; EPITHELIAL CELLS; HUMANS; INTERLEUKIN-6; INTERLEUKIN-8; NAPHTHALENES; PROTEIN KINASE C; SMOKING; TIME FACTORS; TOBACCO SMOKE POLLUTION;

EID: 0033172844     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/ajrcmb.21.2.3636     Document Type: Article

References (27)

1. Wetsel, R. A. 1995. Structure, function and cellular expression of complement unaphylatoxin receptors. Curr. Opin. Immunol. 7:48-53.
2. Buchner, R. R., T. F. Hugli, J. A. Ember, and E. L. Morgan. 1995. Expression of functional receptors for human C5a anaphylatoxin (CD88) on the human hepatocellular carcinoma cell line HepG2. Stimulation of acute-phase protein-specific mRNA and protein synthesis by human C5a anaphylatoxin. J. Immunol. 155:308-315.
3. Gasque, P., P. Chan, M. Fontaine, A. Ischenko, M. Lamacz, O. Gotze, and B. P. Morgan. 1995. Identification and characterization of the complement C5a anaphylatoxin receptor on human astrocytes. J. Immunol. 155:4882-4889.
4. Haviland, D. L., R. L. McCoy, W. T. Whitehead, H. Akama, E. P. Molmenti, A. Brown, J. C. Haviland, W. C. Parks, D. H. Perlmutter, and R. A. Wetsel. 1995. Cellular expression of the C5a anaphylatoxin receptor (C5aR); demonstration of C5aR on nonmyeloid cells of the liver and lung. J. Immunol. 154:1861-1869.
5. Nakamura, H., K. Yoshimura, H. A. Jaffe, and R. G. Crystal. 1991. Interleukin-8 gene expression in human bronchial epithelial cells. J. Biol. Chem. 266:19611-19617.
6. Florcani, A. A., A. J. Heires, L. A. Welniak, A. Miller-Lindholm, L. Clark-Pierce, S. I. Rennard, E. L. Morgan, and S. D. Sanderson. 1998. Expression of receptors for C5a anaphylatoxin (CD88) on human bronchial epithelial cells; enhancement of C5a-mediated release of IL-8 upon exposure to cigarette smoke. J. Immunol. 160:5073-5081.
7. Buhl, A. M., S. Osawa, and G. L. Johnson. 1995, Mitogen-activated protein kinase activation requires two signal inputs from the human anaphylatoxin C5a receptor. J. Biol. Chem. 270:19828-19832.
8. Kalra, V. K., Y. Ying, K. Deemer, R. Natarajan, J. L. Nadler, and T. D. Coates. 1994. Mechanism of cigarette smoke condensate induced adhesion of human monocytes to cultured endothelial cells. J. Cell. Physiol. 160: 154-162.
9. Shen, Y., V. Rattan, C. Sultana, and V. K. Kalra. 1996. Cigarette smoke condensate-induced adhesion molecule expression and transendothelial migration of monocytes. Am. J. Physiol. 270:H1624-H1633.
10. Gopalakrishna, R., Z. H. Chen, and U. Gundimeda. 1994. Tobacco smoke tumor promoters, catechol and hydroquinone, induce oxidative regulation of protein kinase C and influence invasion and metastasis of lung carcinoma cells. Proc. Natl. Acad. Sci. USA 91:12233-12237.
11. Wyatt, T. A., H. Ito, T. J. Veys, and J. R. Spurzem. 1997. Stimulation of protein kinase C activity by tumor necrosis factor-alpha in bovine bronchial epithelial cells. Am. J. Physiol. 273:L1007-L1012.
12. Wyatt, T. A., T. J. Veys, D. J. Tuma, and J. R. Spurzem. 1997. Acetaldehyde and malondialdehyde stimulate protein kinase C synergistically in bovine bronchial epithelial cells. Am. J. Respir. Crit. Care Med. 155:A755.
13. Kelsen, S. G., I. A. Mardini, S. Zhou, J. L. Henovic, and N. C. Higgins. 1992. A technique to harvest viable tracheobronchial epithelial cells from living human donors. Am. J. Respir. Cell Mol. Biol. 7:66-72.
14. Hannun, Y. A. 1985. Activation of protein kinase C by Triton x-100 mixed micelles containing diacylglycerol and phosphatidylserine. J. Biol. Chem. 260:10039-10043.
15. Roskoski, R. 1983. Assays of protein kinase. Methods Enzymol. 99:3-6.
16. Mio, T., D. J. Romberger, A. B. Thompson, R. A. Robbins, A. Heires, and S. I. Rennard. 1997. Cigarette smoke induces interleukin-8 release from human bronchial epithelial cells. Am. J. Respir. Crit. Care Med. 155:1770-1776.
17. Eriksson, C. J. P., H. W. Sippel, and O. A. Forsander. 1977. The determination of acetaldehyde in biological samples by head-space gas chromatography. Anal. Biochem. 80:116-124.
18. Lechner, J. F., and M. A. LaVeck. 1985. A serum-free method for culturing normal human bronchial epithelial cells at clonal density. J. Tiss. Cutr. Methods 9:43-48.
19. Miysikawa, H., E. Baraona, J. C. Chang, M. D. Lesser, and C. S. Licher. 1986. Oxidation of ethanol to acetaldehyde by bronchopulmonary washings: role of bacteria. Alcoholism: Clin. Exp. Res. 10:517-520.
20. Albert, R. E., H. T. Peterson, D. E. Bohning, and M. Lippman, 1975. Short term effects of cigarette smoking on bronchial clearance in humans. Arch. Environ. Health 30:361-367.
21. Venizelos, P. C., T. R. Gerrity, and D. B. Yeates. 1981. Response of human mucociliary clearance to acute alcohol administration. Arch. Environ. Health 36:194-201.
22. Sisson, J. H., and D. J. Tuma. 1994. Vapor phase exposure to acetaldehyde generated from ethanol inhibits bovine bronchial epithelial cell ciliary motility. Alcoholism: Clin. Exp. Res. 18:1252-1255.
23. Sisson, J. H., D. J. Tuma, and S. I. Rennard. 1991. Acetaldehyde-mediated cilia dysfunction in bovine bronchial epithelial cells. Am. J. Physiol. 260: L29-L36.
24. Donohue, T. M., D. J. Tuma, and M. F. Sorrell. 1983. Binding of metabolically derived acetaldehyde to hepatic proteins in vitro. Lab. Invest. 49:226-229.
25. Tuma, D. J., R. B. Jennett, and M. F. Sorrell. 1987. The interaction of acetaldehyde with tublin. Ann. NY Acad. Sci. 492:277-286.
26. Lin, R. C., R. S. Smith, and L. Lumeng, 1988. Detection of a protein acetaldehyde adduct in the liver of rats fed alcohol chronically. J. Clin. Invest. 81:615-619.
27. Shirota, F. N., E. G. DeMaster, C. H. Kwon, and H. T. Nagasawa. 1987. Metabolism of cyanamide to cyanide and an inhibitor of aldehyde dehydrogenase (ALDH) by rat liver microsomes. Alcohol. Alcohol. 1:219-223.